Neisseria meningitidis alpha14 (cnl strain): NMO_1624
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Entry
NMO_1624 CDS
T00954
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nmi
Neisseria meningitidis alpha14 (cnl strain)
Pathway
nmi00300
Lysine biosynthesis
nmi00550
Peptidoglycan biosynthesis
nmi01100
Metabolic pathways
nmi01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nmi00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NMO_1624 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NMO_1624 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NMO_1624 (murF)
Enzymes [BR:
nmi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NMO_1624 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CBA07659
UniProt:
C6S8P4
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Position
complement(1754187..1755545)
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AA seq
452 aa
AA seq
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MKPLDLNFICQALKLPMPSESKPVSRIVTDSRDIRVGDVFFALAGGRFDAHDFVEDVLAA
GAAAVVVSREDCVAMDGALKVDDTLAALQTLAKAWRENVNPFVFGITGSGGKTTVKEMLA
AVLRRRFGDNAVLATAGNFNNHIGLPLTLLKLNEKHRYAVIEMGMNHFGELAVLTQIAKP
DAALVNNAMRAHVGCGFDGVGDIAKAKSEIYQGLCSDGMALIPQEDANMAVFKTATLNLN
TRTFGIDSGDVHAENIVLKPLSCEFDLVCGDERAAVVLPVPGRHNVHNAAAAAALSLAAG
LSLNDVAEGLQGFSNIKGRLNVKAGIKGATLIDDTYNANPDSMRAAIDVLARMPAPRIFV
MGDMGELGEDEAAAMHAEVGAYARDQGIEAAYFVGDNSVEAAEKFGADGLWFAAKDPLIQ
VLRHDLPERATVLVKGSRFMQMEEVVEALEDK
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgaaaccactggacctaaatttcatctgccaagccctcaagcttccgatgccgtctgaa
agcaaacccgtgtcgcgcatcgtaaccgacagccgcgacatccgcgtaggcgatgtgttt
ttcgcattggcgggcgggcggtttgacgcgcatgattttgttgaagacgtattggctgcg
ggtgcggcggcggttgtggtttcgcgcgaagattgcgttgcaatggatggcgcgttgaaa
gtcgatgacacgcttgccgcattgcaaacgctggcaaaggcgtggcgcgagaatgtgaac
ccgtttgtgttcggtattaccggctcgggcggtaagacgacggtgaaggaaatgttggct
gcggtattgcgccgccgtttcggcgataatgccgttttggcgacggcaggcaacttcaac
aaccacatcggattgccgttgactttgttgaaattaaacgaaaaacaccgctatgccgtg
attgaaatgggtatgaaccattttggcgaactggcggttttgacacaaatcgccaaaccc
gatgccgcattggtcaacaacgccatgcgcgcccatgtcggctgcggtttcgacggagtg
ggcgatattgccaaagcgaaaagcgagatttatcaaggcttatgttcagacggcatggcg
ctgattcctcaagaagatgccaatatggctgtcttcaaaacggcaacgcttaatttgaat
acgcgcactttcggcatcgatagcggcgatgtccacgcggaaaatatcgtgctgaaaccg
ttgtcgtgcgaatttgatttggtgtgcggcgacgaacgcgccgccgtggtgctgcctgtt
cccggccgccacaatgtccacaacgccgccgctgccgccgcgctgtctttggctgcgggt
ttgagtctgaacgatgtggcggaaggtttgcaaggcttcagcaacatcaaaggccgtctg
aacgtcaaagccggcatcaagggcgcgaccctgattgacgatacctacaacgcgaacccc
gacagcatgagggcagcgattgacgtgttggcgcgtatgcctgcgccgcgcatttttgtg
atgggcgatatgggcgaactgggtgaggacgaagccgccgccatgcacgccgaagtcggc
gcgtacgcccgcgaccaaggcatcgaagcggcttattttgtcggagacaacagcgtcgaa
gcggcggaaaaatttggcgcggacggtttgtggttcgccgccaaagacccgttgattcaa
gtgttgcgccacgatttgcccgaacgcgccaccgtgttggtgaaaggttcgcgctttatg
cagatggaagaagtggtcgaggcattggaggataagtga
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