Neisseria meningitidis alpha710 (serogroup B): NMBB_0457
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Entry
NMBB_0457 CDS
T01932
Name
(GenBank) UDP-MurNAc-pentapeptide synthetase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nmp
Neisseria meningitidis alpha710 (serogroup B)
Pathway
nmp00300
Lysine biosynthesis
nmp00550
Peptidoglycan biosynthesis
nmp01100
Metabolic pathways
nmp01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nmp00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NMBB_0457
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NMBB_0457
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NMBB_0457
Enzymes [BR:
nmp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NMBB_0457
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADO30938
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Position
425081..426439
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AA seq
452 aa
AA seq
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MKPLDLNFICQALKLPMPSESKPVSRIVTDSRDIRAGDVFFALAGGRFDAHDFVEDVLAA
GAAAVVVSREDCVAMDGALKVDDTLTALQMVAKAWRENVNPFVFGITGSGGKTTVKEMLA
AVLRRRFGDNAVLATAGNFNNHIGLPLTLLKLNEKHRYAVIEMGMNHFGELAVLTQIAKP
DAALINNAMRAHVGCGFDGVGDIAKAKSEIYQGLCSDGMALIPQEDANMAVFKTATLNLN
TRTFGIDSGDVHAENIVLKPLSCEFDLVCGDERAAVVLPVPGRHNVHNAAAAAALSLAAG
LSLNDVAEGLKGFSNIKGRLNVKAGIKGATLIDDTYNANPDSMKAAIDVLARMPAPRIFV
MGDMGELGEDEAAAMHAEVGAYARDQGIEAAYFVGDNSVEAAEKFGADGLWFAAKDPLIQ
VLRHDLPERATVLVKGSRFMQMEEVVEALEDK
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgaaaccactggacctaaatttcatctgccaagccctcaagcttccgatgccgtctgaa
agcaaacccgtgtcgcgcatcgtaaccgacagccgcgacatccgcgcgggcgatgtgttt
ttcgcattggcgggcgggcggtttgatgcgcatgattttgttgaagacgtattggctgct
ggtgcggcggcggttgtggtttcgcgcgaagattgcgttgcaatggatggcgcgttgaaa
gtcgatgacacgcttaccgcgttgcaaatggtggcgaaggcgtggcgcgagaatgtgaac
ccgtttgtgttcggtattaccggttcgggcggcaagacgacggtgaaggaaatgttggct
gcggtattgcgccgccgtttcggcgataatgccgttttggcgacggcaggcaacttcaac
aaccacatcggattgccgttgactttgttgaaattaaacgaaaaacaccgctatgccgtc
atcgaaatgggcatgaaccattttggcgaactggcggttttgacacaaatcgccaaaccc
gatgccgctttgatcaacaacgccatgcgcgcccatgtcggctgcggttttgacggagtg
ggcgatattgccaaagcgaaaagcgagatttatcaaggcttatgttcagacggcatggca
ctgattcctcaagaagatgccaatatggctgtcttcaaaacggcaacgcttaatttgaat
acgcgcactttcggcatcgatagcggcgatgtccacgcggaaaatatcgtgctgaaaccg
ttgtcgtgcgaatttgatttggtgtgcggcgacgaacgcgccgccgtggtgctgcctgtt
cccggccgccacaatgtccacaacgccgccgctgccgccgcgctgtctttggctgcaggt
ttgagtttgaacgatgtggcggaaggtttgaaaggcttcagcaatatcaaaggccgtctg
aacgtcaaagccggcatcaagggcgcgaccctgattgacgatacttataatgcgaacccg
gacagcatgaaagccgcgattgacgtgttggcgcgtatgcctgcgccgcgtattttcgta
atgggcgatatgggcgaactgggcgaggacgaagccgccgctatgcacgccgaagtcggt
gcgtatgcccgcgaccaaggcatcgaagcggcttattttgtcggcgacaacagcgtcgaa
gcggcggaaaaatttggcgcggacggtttgtggtttgccgccaaagacccgttgattcaa
gtgttgcgccacgatttgcccgaacgcgccaccgtgttggtgaaaggttcgcgctttatg
cagatggaagaagtggtcgaggcattggaggataagtga
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