Neisseria meningitidis 8013 (serogroup C): NMV_2196
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Entry
NMV_2196 CDS
T01928
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase (FGAM synthase; FGAMS; formylglycinamide ribotide amidotransferase; FGARAT; formylglycinamide ribotide synthetase)
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
nmt
Neisseria meningitidis 8013 (serogroup C)
Pathway
nmt00230
Purine metabolism
nmt01100
Metabolic pathways
nmt01110
Biosynthesis of secondary metabolites
Module
nmt_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
nmt00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NMV_2196 (purL)
Enzymes [BR:
nmt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NMV_2196 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
CAX50958
UniProt:
A0A9K2KQP5
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All DBs
Position
2113310..2117296
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AA seq
1328 aa
AA seq
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MSVVLPLRGVTALSDFRVEKLLQKAAALGLPEVKLSSEFWYFVGSEKALDAATVEKLQAL
LAAQSVEQTPKAREGLHLFLVTPRLGTISPWASKATNIAENCGLAGIERIERGMAVWLEG
ALTDEQKRQWAALLHDRMTESVLPDFQTASKLFHHLESETFSTVDVLGGGKEALVKANTE
MGLALSADEIDYLVENYQALQRNPSDVELMMFAQANSEHCRHKIFNADFILNGEKQPKSL
FGMIRDTHNAHPEGTVVAYKDNSSVIEGAKIERFYPNAAENQGYRFHEEDTHIIMKVETH
NHPTAIAPFAGAATGAGGEIRDEGATGKGSRPKAGLTGFTVSNLNIPDLKQPWEQDYGKP
EHISSPLDIMIEGPIGGAAFNNEFGRPNLLGYFRTFEEKFDGQVRGYHKPIMIAGGLGSI
QAQQTHKDEIPEGALLIQLGGPGMLIGLGGGAASSMDTGTNDASLDFNSVQRGNPEIERR
AQEVIDRCWQLGDKNPIISIHDVGAGGLSNAFPELVNDAGRGAVFKLREVPLEEHGLNPL
QIWCNESQERYVLSILEKDLDTFRAICERERCPFAVVGTATDDGHLKVRDDLFSNNPVDL
PLNVLLGKPPKTTRTDKTVTPYATEGNPFGKKPFNAGNIDITEAAYRVLRLPTVAAKNFL
ITIGDRSVGGLTHRDQMVGKYQTPVADCAVTMMGFNTYRGEAMSMGEKPTVALFDAPASG
RMCVGEAITNIAAVNIGDIGNIKLSANWMAACGNEGEDEKLYRTVEAVSKACQALDLSIP
VGKDSLSMKTVWQDGEEKKSVVSPLSLIISAFAPVQDVRKTVTPELKNVEDSVLLFVDLG
FGKARMGGSAFGQVYNNMSGDAPDLDDTGRLKDFYGVIQQLVAEDKLLAYHDRSDGGLFA
VLVEMAFAGRCGLDIDLNLLLAQTFITNHTALSQSLRTEEVKALAEWQETIARTLFNEEL
GAVIQVRKQDVADIINLFYQQQLHHNVFEIGTLTDENTLIIRDGQTHLISDNLIKLQQTW
QETSHQIQRLRDNPACADSEFALIGDNERSALFADLKFDVNEDIAAPFINSGAKPKIAIL
REQGVNGQIEMAAAFTRAGFDAYDVHMSDLMAGRFRLADFKMLAACGGFSYGDVLGAGEG
WAKSILFHPALRDQFAAFFADPDTLTLGVCNGCQMVSNLAEIIPGAEAWPKFKRNLSEQF
EARLSMVHVPKSASLILNEMQGSSLPVVVSHCEGRADFALHGGNISADLGIALQYVDGQN
QVTQTYPLNPNGSPQGIAGITNADGRVTIMMPHPERVYRAAQMSWKPEGWTELSGWYRLF
AGARKALG
NT seq
3987 nt
NT seq
+upstream
nt +downstream
nt
atgtctgtcgttttgcccttgcgcggcgttaccgccctttccgatttccgtgttgaaaaa
ctcttgcaaaaagccgccgcactcggtctgcccgaagtcaaattaagcagcgaattttgg
tatttcgtcggcagcgagaaagcattggatgccgcgactgtcgaaaaactgcaagccttg
ttggcggcgcaaagcgttgaacaaacgccaaaagcgcgcgagggcttgcatttgtttttg
gtcacgccccgtttgggtacgatttcgccgtgggcttccaaggcgaccaatatcgcggaa
aactgcggtttggcaggcatcgagcgcatcgagcgcggcatggcggtgtggctggaaggt
gcgcttaccgatgaacagaaacggcaatgggcggctttgctgcacgaccgcatgaccgaa
tccgtattgcccgattttcagacggcctccaaattattccaccatctcgaatccgaaacc
ttttccaccgttgatgttttaggcggcggtaaagaggctttggtcaaagccaataccgaa
atgggtttggcactctccgccgacgaaatcgattatctggttgaaaactatcaggctttg
cagcgcaatccgtccgatgttgaattgatgatgttcgcgcaggcaaacagcgaacactgc
cgccacaaaatcttcaacgccgacttcatcctcaacggcgaaaaacaaccgaaatccctg
ttcggtatgatacgcgacacgcacaacgcgcatcccgaaggcacggtcgtcgcttataaa
gacaactcgtccgtaattgaaggcgcgaaaatcgagcgtttctatccgaatgcggcggaa
aaccaaggttaccgtttccacgaagaagacacgcatatcatcatgaaagtggaaacgcac
aaccacccgaccgccatcgcgccgtttgcgggcgcggcaacaggcgcgggcggcgaaatc
cgcgacgaaggcgcaacgggcaaaggttcgcgtccgaaagcaggcttgaccggctttacc
gtctccaacctcaacatccccgacctcaaacagccgtgggaacaagactacggcaagccg
gaacacatttcctccccgttggacatcatgattgaaggccccatcggcggcgcggcgttc
aacaacgaattcggccgccccaacctcttgggctacttccgcacttttgaagagaagttt
gacggtcaggttcgcggctaccacaaaccgattatgattgccggcggcttgggcagcatt
caggcgcagcagacgcataaagacgaaatccccgaaggcgcgttgctgatccaactgggc
ggcccgggcatgcttatcggcttgggcggcggcgcggcttcttcgatggataccggcacg
aacgacgcgtctttagacttcaattccgtacaacgcggcaaccccgaaatcgaacgccgc
gcgcaggaagtcatcgaccgctgctggcagcttggcgacaaaaacccgattatctccatc
cacgacgtcggcgctggcggcttgtccaacgccttccccgaactcgtcaacgatgccgga
cgcggcgcggtattcaagctgcgcgaagtgccgttggaagaacacggtctcaacccgctg
caaatctggtgcaacgaatcgcaagagcgttatgtgttgtcgattttggaaaaagatttg
gacaccttccgcgccatctgcgaacgcgaacgctgcccatttgccgtagtcggcacggcg
accgacgacggccatttgaaagtgcgcgacgacttgttctccaacaaccctgtcgatttg
ccgctgaacgtcttgctcggcaaaccgcccaaaaccacgcgcaccgataaaacggttacg
ccgtatgcgaccgaagggaatccctttgggaaaaaaccgtttaacgcgggcaatatcgac
atcaccgaagccgcctaccgcgttttgcgcctgcctaccgtagccgccaaaaacttcctg
attactatcggcgaccgcagcgtcggcggtttgacccaccgcgaccaaatggtcggcaaa
taccaaacccccgtagccgactgcgccgttactatgatgggcttcaacacctatcgcggc
gaagcgatgagcatgggcgaaaaaccgaccgtcgccctgtttgacgcgcctgcttcgggc
cgaatgtgcgtcggcgaagccatcaccaacatcgcggcggtcaacatcggcgacatcggc
aacatcaaactttccgccaactggatggcggcgtgcggcaacgaaggcgaagacgaaaaa
ctctaccgcaccgtcgaagccgtttctaaagcctgtcaggcattggatttgagcattccc
gtgggcaaagacagcctgtcgatgaaaaccgtatggcaggacggcgaagagaaaaaatcc
gtcgtctcgccgttgagcctgattatctctgcgttcgcgccggttcaagacgtgcgcaaa
accgttacgcccgaattgaaaaacgtcgaagacagcgtattgttgtttgttgatttgggt
tttggcaaagcgcgtatgggcggctcggcgtttggtcaggtgtacaacaatatgagcggc
gacgcgcccgatttggacgatacaggccgtctgaaagacttttacggcgtgattcaacag
cttgtcgccgaagacaaactcttggcgtatcacgaccgcagcgacggcggcttgtttgcc
gttttggtagaaatggcgtttgcagggcggtgcggcttggatatagatttaaatttattg
cttgcacaaacatttattaccaaccataccgctctgtctcaatcattgcggactgaagag
gtaaaagcgttggctgaatggcaagaaaccattgcccgcacattatttaatgaagagttg
ggtgctgttatccaagttagaaaacaagatgttgccgatattatcaatttattctatcaa
caacagctgcatcataatgtctttgaaatcggtacgttaactgatgagaacacgttaatc
atccgcgacgggcaaacgcaccttatttctgacaacctaatcaaactgcaacaaacctgg
caagaaaccagccatcaaatccaacgcctgcgcgacaaccctgcctgcgccgacagcgag
ttcgcactgattggcgacaacgaacgcagcgcattgtttgccgacctgaaattcgacgtg
aacgaagacatcgccgcgccgtttatcaacagcggcgcgaaacccaaaatcgccatcctg
cgcgaacagggcgtaaacgggcaaatcgaaatggccgccgcctttacccgcgccggtttc
gatgcttacgacgtgcatatgtccgacctgatggcaggccgtttccgccttgccgacttc
aaaatgctggcggcgtgcggcggcttcagctacggcgacgtactcggcgcgggcgaaggc
tgggcgaaatccatcctgttccaccctgctctgcgcgaccagtttgccgcattcttcgcc
gacccggacacgctgacattgggcgtgtgcaacggctgccaaatggtcagcaacctcgcc
gagattatcccgggtgcagaggcatggccgaagttcaaacgtaacttgagcgaacagttc
gaagcgcgcctgagtatggttcacgtccccaaatccgcgtcgctgattctgaacgaaatg
caaggctccagcctgcctgtcgtggtcagccactgcgaaggccgcgccgacttcgcgctt
cacggcggcaatatttccgccgatttgggcatcgcgctgcaatatgtggacggtcaaaac
caggttacccaaacctatccgctcaaccccaacggctcgccgcaaggcatcgccggcatt
accaacgccgacggccgcgtgaccatcatgatgccccaccccgaacgcgtgtaccgcgcc
gcgcaaatgagctggaaaccggaaggctggacggaactgtccggctggtaccgcctcttt
gccggcgcacgtaaagccttgggctaa
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