Neisseria meningitidis WUE 2594 (serogroup A): NMAA_0941
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Entry
NMAA_0941 CDS
T01931
Symbol
hom
Name
(GenBank) homoserine dehydrogenase (HDH)
KO
K00003
homoserine dehydrogenase [EC:
1.1.1.3
]
Organism
nmw
Neisseria meningitidis WUE 2594 (serogroup A)
Pathway
nmw00260
Glycine, serine and threonine metabolism
nmw00270
Cysteine and methionine metabolism
nmw00300
Lysine biosynthesis
nmw01100
Metabolic pathways
nmw01110
Biosynthesis of secondary metabolites
nmw01120
Microbial metabolism in diverse environments
nmw01230
Biosynthesis of amino acids
Module
nmw_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
nmw00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
NMAA_0941 (hom)
00270 Cysteine and methionine metabolism
NMAA_0941 (hom)
00300 Lysine biosynthesis
NMAA_0941 (hom)
Enzymes [BR:
nmw01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
NMAA_0941 (hom)
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GFIT
Motif
Pfam:
Homoserine_dh
NAD_binding_3
ACT
ACT_AHAS_ss
ACT_4
DXP_reductoisom
DUF6952
Motif
Other DBs
NCBI-ProteinID:
CBY90838
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Position
1070173..1071480
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AA seq
435 aa
AA seq
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MKPVNIGLLGLGTVGGGTAAVLRDNAEEISRRLGREIRISAVCDLSEEKARQTCPSAAFV
KDPFELVAREDVDVVVELFGGTGIAKDAVLKAIENGKHIVTANKKLLAEYGNEIFPLAEK
QNVIVQFEAAVAGGIPIIKALREGLAANRIKSIAGIINGTSNFILSEMREKGSAFADVLK
EAQALGYAEADPTFDIEGNDAGHKITIMSALAFGTPMNFSACYLEGISKLDSRDIKYAEE
LGYRIKLLGITRKTGKGIELRVHPTLIPESRLLANVNGVMNAVRVNADMVGETLYYGAGA
GALPTASAVVADIIDIARLVEADTAHRVPHLAFQPAQVQAQTILPMDEITSSYYLRVQAK
DEPGTLGQIAALLAQENVSIEALIQKGVIDQTTAEIVILTHSTVEKHIKSAIAAIEALDC
VEKPITMIRMESLHD
NT seq
1308 nt
NT seq
+upstream
nt +downstream
nt
atgaagccagtaaacatcggtcttttaggtttgggtacggtcggcggcggtacggctgcc
gtgttgcgggacaacgcggaggaaatttcccgtcgcttggggcgcgaaatccgtatttct
gccgtgtgcgatttgagtgaagaaaaagcccgacaaacctgcccgtccgcagcctttgtc
aaagatccgttcgaactggtcgcacgtgaagacgtcgatgtcgtcgtcgaattgttcggc
ggtaccggcattgccaaagatgcggtgttgaaagccattgaaaacggcaaacacatcgtt
accgccaacaaaaaactgctcgccgaatacggcaacgaaatcttcccgctggcggaaaaa
caaaacgtcatcgtccaatttgaagcggcagtagcgggcggtatcccaatcatcaaagcc
ctgcgcgaaggtttggcggcaaacaggattaaatccatcgccggcattattaacggcacc
agcaacttcatcctctccgaaatgcgcgaaaaaggcagcgcgtttgccgatgtactgaaa
gaagcgcaggcattgggttatgccgaagccgatccgaccttcgacatcgaaggcaacgat
gcgggccataaaatcaccatcatgagcgcactggcattcggcacgccgatgaacttttcc
gcctgctacctcgaaggcatcagcaaactcgacagccgcgacatcaaatacgccgaagaa
cttggctatcgcatcaaactgttgggcattacccgcaaaaccggcaaaggcatcgagctg
cgcgtccaccctaccctgattcccgaaagccgcctcttggcaaacgtcaacggcgtgatg
aacgccgtgcgcgtcaacgccgatatggttggcgaaaccttatattacggcgcgggcgcg
ggcgcattgccgaccgcttccgccgtggttgccgatatcatcgacatcgcccgcctggtt
gaagccgataccgcccaccgcgtaccgcatctggcgttccaacccgcgcaagtccaagcg
caaaccatcctgcctatggacgaaattaccagcagctactacctgcgcgtccaagccaaa
gacgaaccgggcacgctggggcaaatcgccgcgctgttggcacaagaaaacgtgtccatc
gaagcactgattcaaaaaggcgtgattgatcagaccactgccgaaatcgtgattctgacc
cacagcacggtcgaaaaacacatcaagtcggcaatcgcagccatcgaagcactggattgc
gtggaaaaaccgattaccatgatccgcatggaaagcctgcatgactga
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