Neisseria meningitidis WUE 2594 (serogroup A): NMAA_1519
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Entry
NMAA_1519 CDS
T01931
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alan ine ligase (UDP-MurNAc-pentapeptide synthetase; D-alanyl-D-alanine-adding enzyme)
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nmw
Neisseria meningitidis WUE 2594 (serogroup A)
Pathway
nmw00300
Lysine biosynthesis
nmw00550
Peptidoglycan biosynthesis
nmw01100
Metabolic pathways
nmw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nmw00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NMAA_1519 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NMAA_1519 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NMAA_1519 (murF)
Enzymes [BR:
nmw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NMAA_1519 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CBY91455
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Position
complement(1780672..1782030)
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AA seq
452 aa
AA seq
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MKPLDLNFICQALKLPMPSESKPVSRIVTDSRDIRAGDVFFALAGGRFDAHDFVEDVLAA
GAAAVVVSREDCVAMDGALKVDDTLAALQMVAKAWRENVNPFVFGITGSGGKTTVKEMLA
AVLRRRFGDNAVLATAGNFNNHIGLPLTLLKLNEKHRYAVIEMGMNHFGELAVLTQIAKP
DAALVNNAMRAHVGCGFDGVGDIAKAKSEIYQGLCSDGMALIPQEDANMAVFKTATLNLN
TRTFGIDSGDVHAENIVLKPLSCEFDLVCGDERAAVVLPVPGRHNVHNAAAAAALSLAAG
LSLNDVAEGLKGFSNIKGRLNVKSGIKGATLIDDTYNANPDSMKAAIDVLARMPAPRIFV
MGDMGELGEDEAAAMHAEVGAYARDQGIEAAYFVGDNSVEAAEKFGADGLWFAAKDPLIQ
VLRHDLPERATVLVKGSRFMQMEEVVEALEDK
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgaaaccactggacctaaatttcatctgccaagccctcaagcttccgatgccgtctgaa
agcaaacccgtgtcgcgcatcgtaaccgacagccgcgacatccgcgcgggcgatgtgttt
ttcgcattggcgggcgggcggtttgatgcgcatgattttgttgaagacgtattggctgct
ggtgcggcggcggttgtggtttcgcgcgaagattgcgttgcaatggatggcgcgttgaaa
gtcgatgacacgcttgccgcattgcaaatggtggcgaaggcgtggcgcgagaatgtgaac
ccgtttgtgttcggtattaccggttcgggcggtaagacgacggtgaaggaaatgttggct
gcggtattgcgccgccgtttcggcgataatgccgttttggcgacggcaggcaacttcaac
aaccacatcggattgccgttgactttgttgaaattaaacgaaaaacaccgctatgccgtg
attgaaatgggtatgaaccattttggtgaactggcggttttgacacaaatcgccaaaccc
gatgccgcattggtcaacaacgccatgcgcgcccatgtcggctgcggtttcgacggagtg
ggcgatattgccaaagcgaaaagcgagatttatcaaggcttatgttcagacggcatggca
ctgattcctcaagaagatgccaatatggctgtcttcaaaacggcaacgcttaatttgaat
acgcgcactttcggcatcgatagcggcgatgtccacgcggaaaatatcgtgctgaaaccg
ttgtcgtgcgaatttgatttggtgtgcggcgacgaacgcgccgccgtggtgctgcctgtt
cccggccgccacaatgtccacaacgccgccgctgccgccgcgctgtctttggctgcaggt
ttgagtttgaacgatgtggcggaaggtttgaaaggcttcagcaatatcaaaggccgtctg
aacgtcaaatccggaatcaagggcgcaaccctgattgacgatacttataatgcgaaccct
gacagcatgaaagctgcgattgacgtgttggcgcgtatgcctgcgccgcgtattttcgtg
atgggcgatatgggcgaactgggtgaggacgaagccgccgccatgcacgccgaagtcggc
gcgtatgctcgcgaccaaggcatcgaagcggcttattttgtcggcgacaacagcgtcgaa
gcggcggaaaaatttggcgcggacggtttgtggttcgccgccaaagacccgttgattcaa
gtgttgcgccacgatttgcccgaacgcgccaccgtgttggtgaaaggttcgcgctttatg
cagatggaagaagtggtcgaggcattggaggataagtga
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