Neisseria meningitidis 510612 (serogroup A): NMA510612_2335
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Entry
NMA510612_2335 CDS
T03438
Symbol
murF
Name
(GenBank) UDP-MurNAc-pentapeptide synthetase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nmx
Neisseria meningitidis 510612 (serogroup A)
Pathway
nmx00300
Lysine biosynthesis
nmx00550
Peptidoglycan biosynthesis
nmx01100
Metabolic pathways
nmx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nmx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NMA510612_2335 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NMA510612_2335 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NMA510612_2335 (murF)
Enzymes [BR:
nmx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NMA510612_2335 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AHW76601
UniProt:
X5ESW5
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Position
complement(2018650..2020089)
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AA seq
479 aa
AA seq
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MFYHSKTGDKKSAATDVSAARILTKVNMKPLDLNFICQALKLPMPSESKPVSRIVTDSRD
IRAGDVFFALAGGRFDAHDFVEDVLAAGAAAVVVSREDCVAMDGALKVDDTLAALQMVAK
AWRENVNPFVFGITGSGGKTTVKEMLAAVLRRRFGDNAVLATAGNFNNHIGLPLTLLKLN
EKHRYAVIEMGMNHFGELAVLTQIAKPDAALVNNAMRAHVGCGFDGVGDIAKAKSEIYQG
LCSDGMALIPQEDANMAVFKTATLNLNTRTFGIDSGDVHAENIVLKPLSCEFDLVCGDER
AAVVLPVPGRHNVHNAAAAAALSLAAGLSLNDVAEGLKGFSNIKGRLNVKSGIKGATLID
DTYNANPDSMKAAIDVLARMPAPRIFVMGDMGELGEDEAAAMHAEVGAYARDQGIEAAYF
VGDNSVEAAEKFGADGLWFAAKDPLIQVLRHDLPERATVLVKGSRFMQMEEVVEALEDK
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
gtgttttaccacagtaaaacaggcgataaaaaatcagccgctaccgatgtgtccgccgcc
cgaatattaacgaaagtaaatatgaaaccactggacctaaatttcatctgccaagccctc
aagcttccgatgccgtctgaaagcaaacccgtgtcgcgcatcgtaaccgacagccgcgac
atccgcgcgggcgatgtgtttttcgcattggcgggcgggcggtttgatgcgcatgatttt
gttgaagacgtattggctgctggtgcggcggcggttgtggtttcgcgcgaagattgcgtt
gcaatggatggcgcgttgaaagtcgatgacacgcttgccgcattgcaaatggtggcgaag
gcgtggcgcgagaatgtgaacccgtttgtgttcggtattaccggttcgggcggtaagacg
acggtgaaggaaatgttggctgcggtattgcgccgccgtttcggcgataatgccgttttg
gcgacggcaggcaacttcaacaaccacatcggattgccgttgactttgttgaaattaaac
gaaaaacaccgctatgccgtgattgaaatgggtatgaaccattttggcgaactggcggtt
ttgacacaaatcgccaaacccgatgccgcattggtcaacaacgccatgcgcgcccatgtc
ggctgcggtttcgacggagtgggcgatattgccaaagcgaaaagcgagatttatcaaggc
ttatgttcagacggcatggcactgattcctcaagaagatgccaatatggctgtcttcaaa
acggcaacgcttaatttgaatacgcgcactttcggcatcgatagcggcgatgtccacgcg
gaaaatatcgtgctgaaaccgttgtcgtgcgaatttgatttggtgtgcggcgacgaacgc
gccgccgtggtgctgcctgttcccggccgccacaatgtccacaacgccgccgctgccgcc
gcgctgtctttggctgcaggtttgagtttgaacgatgtggcggaaggtttgaaaggcttc
agcaatatcaaaggccgtctgaacgtcaaatccggaatcaagggcgcaaccctgattgac
gatacttataatgcgaaccctgacagcatgaaagctgcgattgacgtgttggcgcgtatg
cctgcgccgcgtattttcgtgatgggcgatatgggcgaactgggtgaggacgaagccgcc
gccatgcacgccgaagtcggcgcgtatgctcgcgaccaaggcatcgaagcggcttatttt
gtcggcgacaacagcgtcgaagcggcggaaaaatttggcgcggacggtttgtggttcgcc
gccaaagacccgttgattcaagtgttgcgccacgatttgcccgaacgcgccaccgtgttg
gtgaaaggttcgcgctttatgcagatggaagaagtggtcgaggcattggaggataagtga
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