Neisseria meningitidis NZ-05/33 (serogroup B): NMBNZ0533_0740
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Entry
NMBNZ0533_0740 CDS
T01949
Symbol
folC
Name
(GenBank) tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
nmz
Neisseria meningitidis NZ-05/33 (serogroup B)
Pathway
nmz00790
Folate biosynthesis
nmz01100
Metabolic pathways
nmz01240
Biosynthesis of cofactors
Module
nmz_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
nmz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
NMBNZ0533_0740 (folC)
Enzymes [BR:
nmz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
NMBNZ0533_0740 (folC)
6.3.2.17 tetrahydrofolate synthase
NMBNZ0533_0740 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
ADZ03191
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Position
complement(795113..796387)
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AA seq
424 aa
AA seq
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MKTLQDWLSHLETAHSGGLIDMGLERVGEVKKRMKLTPQCPVVVVAGTNGKGSVCAYLTQ
IYKQAGYKTGTLTSPHLLRYNERIAINAEPVSDDTIIASFERIEAARSEISLTYFEFNTL
AAVDIFMREQVDVMILEVGLGGRLDAVNAFDGDCAVVTSVDLDHQAFLGDTVEQVGFEKA
GVFRSGKPAICGQNPAPKSLLSHAEAIGAKLLMVQRDFEFHALENIQWNYHFRPQHSDSP
ARNRNSLPFPALRGAYQLSNAACALTVLECLNDKLPVDIGAIKRGLLLVENPGRFQVLPG
RPLTVLDVGHNPHAARALRRSLINLAFAQKRTAVFSMLSDKDIDGVLEIVKDQFDEWYIA
PLDMPRGMTLESLQNKLHEHSIENIQTFAAVREAYRAAASKAGENDRIVVFGSFHTVADV
MSVL
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgaaaacactgcaagactggctctcgcatttggaaaccgcccacagcggcggcttgatc
gatatgggcttggaacgcgtaggcgaagtgaaaaaacggatgaagctcacgccgcaatgc
cccgtcgtcgttgtcgcgggaacaaacggcaaaggttcggtctgcgcctacctgacacag
atttacaaacaggcgggctacaaaaccggcacactgaccagcccgcatttattgcgttac
aacgaacgcatcgccatcaacgccgaacccgtttcggacgatacgattattgcctctttc
gagcgcatcgaagcggcgcgcagcgaaatatcgctgacttattttgaattcaatacgttg
gcggccgtcgacatcttcatgcgcgaacaggttgacgtgatgatattggaagtcggcttg
ggcggacgcttggacgcggtcaacgcgtttgacggcgattgcgcggtggttaccagcgtg
gatttggaccatcaggcatttttgggcgatacggtcgagcaggtcggctttgaaaaagca
ggcgtgttccgtagcggcaaacccgccatctgcggtcaaaaccccgcgcccaaatcgttg
ctttcacacgccgaagccataggcgcgaaactgctgatggtgcagcgcgatttcgagttt
cacgcgctggaaaacatccaatggaactaccacttccgaccgcagcattcagacagcccc
gctcgcaaccgtaattccctgcccttccccgcattgcgcggcgcataccaactttccaat
gccgcctgtgcgctgaccgtgttggaatgtttgaacgacaaattgccggtggacatcggt
gcaatcaaacgcggattgctgctggttgaaaatcccggacgcttccaagtcctgcccggc
cggccgctgaccgttttggacgtcggacacaatccccacgctgcccgcgccctgcgccgc
agcctgattaatttggcgtttgcgcaaaaacgcaccgccgtgttcagtatgctgtccgac
aaagacatagacggcgtgttggaaattgtcaaagaccagtttgacgaatggtatatcgca
cctttggacatgccgcgcggcatgacgctcgagagcctgcaaaacaaactgcacgaacac
agcatcgaaaacatacagacattcgccgccgtccgcgaagcataccgggcggcagcctca
aaagcgggcgagaacgacagaatcgtcgttttcggctcatttcataccgttgccgatgtc
atgtcggtactttaa
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