Nestor notabilis (Kea): 104412421
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Entry
104412421 CDS
T08494
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
nnt
Nestor notabilis (Kea)
Pathway
nnt00270
Cysteine and methionine metabolism
nnt00480
Glutathione metabolism
nnt01100
Metabolic pathways
nnt01240
Biosynthesis of cofactors
nnt04216
Ferroptosis
Module
nnt_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
nnt00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
104412421 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
104412421 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
104412421 (GCLC)
Enzymes [BR:
nnt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
104412421 (GCLC)
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Paralog
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
104412421
NCBI-ProteinID:
XP_010021445
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All DBs
Position
Unknown
AA seq
583 aa
AA seq
DB search
MLVKFDHENKKVRLVLCGEEVLQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGT
MSEFNTVQDNMRKRRQEAASVLKENEAICTVTSFPRLGCPGFTVPEYKPTPVEGGASKSL
FFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPDDDGEAAKAAK
PDYIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSD
IDCRWGVISASVDDRTREERGLEPLKNNLYRISKSRYDSIDSYLSECGEKYNDIDLTIDK
DIYEHLIKEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFK
PPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKV
AQKRDAVRQGMFYFRKDICKGGNAVVDGCSSAQNGTGTNTEEYTLMSIDTIINGKEGVFP
GLIPILNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSM
ITDEMNYSLIWKCNQIAQGQAECPELLGVGFNKKQSGNRTGSL
NT seq
1752 nt
NT seq
+upstream
nt +downstream
nt
atgttagtgaaatttgaccatgagaataagaaagtgcgcttggtgctctgtggtgaagaa
gttcttcaaacactgcaagacaaaggggagaaggtaaaccccaaccacccaacactctgg
cgaccagaatatggaagctatatgattgaagggacgcctgggcagccatatgggggaacc
atgtctgaatttaacaccgtgcaggacaacatgaggaaaagacggcaagaggctgcttct
gttctcaaagaaaatgaggctatttgcactgtgacatcatttccacggttagggtgtcct
gggtttacagtgccggaatataagccaacgccagtagaaggaggagcttcaaaatccctg
ttttttccagacgaagccatcaataaacatcctagatttagtacactgaccagaaacatt
cggcaccgaagaggagagaaggttgtgataaatgtaccaatatttaaagataagaacacg
ccatcaccatttatcgaaacgtttcctgatgatgatggagaagcagcaaaggcagcaaag
ccagactacatatacatggatgctatgggatttggaatgggaaactgctgtcttcaggta
acattccaggcttgcagcatttctgaagcaaggtatctctatgatcagctagccacgatc
tgtcccattgtgatggcgttgagtgctgcatctccattctacagaggctacgtgtctgat
attgactgtcgctggggagtaatttctgcatctgtagatgatagaacgcgagaagaaagg
gggctagagccactgaagaacaacctttatagaatcagtaaatccagatatgattccata
gacagttatctatctgaatgtggtgagaaatacaatgacattgatttgacaatagacaaa
gatatctacgagcatctaataaaggaaggtattgaccaccttttggcacagcatattgca
cacttgttcattcgagacccattgactttgtttgaggagaaaatacatctagatgatgca
aatgaatccgaccattttgagaatattcagtctacaaactggcagacaatgaggtttaag
ccacctcctccaaattcggatattggatggagagtggaattcagacctatggaggtccag
ttaacagactttgaaaactctgcatatgttgtgttcgtggtgttgctaaccagagtgatt
ctgtcatataaactggattttctcattcctttgtccaaggtggatgaaaacatgaaggtg
gcccagaaaagagatgctgtccggcagggaatgttttacttcagaaaagatatttgcaaa
ggtggaaacgctgttgtggatggatgtagctctgcacagaatgggacaggcaccaacaca
gaagagtacaccttaatgagcattgatacaattatcaatgggaaggaaggagtctttcct
ggtttgatcccaattttgaattcctatcttgaaaacatggaagtggatgtggacacaagg
tgcaccatcctaaactacctgaagctaataaaaaagagagcatctggagaactgatgaca
gttgctcgatggatgagggaatttatcgcacagcatccagactacaagcaagacagcatg
ataactgatgaaatgaattacagccttatttggaaatgcaaccaaatcgcacaaggccag
gcagagtgcccagaactgttgggggtaggatttaataagaaacaaagcggaaacagaacc
ggctctttgtaa
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