Nocardiopsis sp. LDBS0036: UIS43_25355
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Entry
UIS43_25355 CDS
T11195
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
nocb Nocardiopsis sp. LDBS0036
Pathway
nocb00290
Valine, leucine and isoleucine biosynthesis
nocb00620
Pyruvate metabolism
nocb01100
Metabolic pathways
nocb01110
Biosynthesis of secondary metabolites
nocb01210
2-Oxocarboxylic acid metabolism
nocb01230
Biosynthesis of amino acids
Module
nocb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
nocb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
UIS43_25355 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
UIS43_25355 (leuA)
Enzymes [BR:
nocb01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
UIS43_25355 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
XEA85487
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Position
5965532..5967232
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AA seq
566 aa
AA seq
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MVPQQKPSPMPFHRYKPFAPVDLPDRTWPSKSITEAPRWLSTDLRDGNQALIEPMDPARK
REMFELLVRMGYKEIEVGFPAASQTDFDFVRSLIEGDAIPDDVQISVLTQAREDLIERTV
QSLVGAKRATVHLYNATAPTFRRVVFRVDREACKDIAVQGTRHVMRFAEQYLGETEYFGY
EYSPEIFIDTELDFALEVCEAVMDVWQPGPGREIILNLPATVERSTPNVYADQIEWMSRS
LSRREHVVVSVHPHNDRGTGVASAELAVMAGADRVEGCLFGHGERTGNVCLVTLGMNLFS
QGVDPRIDFSDIDEIRRTVEHCTQLPVAPRHPYGGDLVYTAFSGSHQDAIKKGFAAQQEA
ADAAGTPVEEHVWDVPYLPIDPKDVGRNYEAVIRVNSQSGKGGVSYIMQRDHSLDLPRRL
QIEFSQVIQKFTDAEGGEFAAGRIWEIFSQTYLAEGGPVAVLAHRSTTDSDGTYRIEADA
RVNGEIRELTGTGNGPISAFCDALTDVDVKVRVMDYVEHSMGGDGDARAAAYVEAEIDGR
VVWGVGIHSSITTASLKALCSAIARV
NT seq
1701 nt
NT seq
+upstream
nt +downstream
nt
atggtgccgcagcaaaagcccagccccatgcccttccaccgctacaagcccttcgcgccg
gtggacctgcccgaccgcacctggccctccaagagcatcaccgaggccccgcgctggctg
tccacggacctgcgcgacggcaaccaggcgctgatcgagccgatggaccccgcccgcaag
cgcgagatgttcgagctgctggtgcggatgggctacaaggagatcgaggtaggtttcccg
gccgccagccagaccgacttcgacttcgtccggtccctgatcgagggcgacgcgatcccc
gacgacgtgcagatctcggtgctgacccaggcccgtgaggacctcatcgagcgcaccgtg
cagagcctggtcggggcgaagcgcgccaccgtgcacctgtacaacgccaccgcgcccacc
ttccgccgtgtcgtcttccgcgtggaccgcgaggcctgcaaggacatcgccgtccagggc
acccggcacgtcatgcgcttcgccgagcagtacctgggcgagaccgagtacttcggctac
gagtactcgcccgagatcttcatcgacaccgagctggacttcgccctggaggtctgcgag
gccgtcatggacgtctggcagcccggcccgggccgcgagatcatcctcaacctgcccgcg
accgtcgagcgctccacgcccaacgtctacgccgaccagatcgagtggatgagccgcagc
ctgtcccggcgcgagcacgtggtcgtctcggtgcacccgcacaacgaccgcggcaccggc
gtggcctcggccgagctggccgtcatggccggggccgaccgcgtcgagggctgcctgttc
gggcacggcgagcgcaccggcaacgtctgcctggtcaccctgggcatgaacctgttcagc
cagggcgtggacccccggatcgacttctccgacatcgacgagatccgccgcaccgtcgag
cactgcacccagctgccggtcgccccgcgccacccctacggcggcgacctggtctacacc
gccttctccggctcccaccaggacgccatcaagaagggcttcgccgcccagcaggaggcc
gccgacgccgcggggaccccggtggaggagcacgtctgggacgtgccctacctgcccatc
gaccccaaggacgtgggccgcaactacgaggccgtcatccgggtcaacagccagtccggc
aagggcggcgtctcctacatcatgcagcgcgaccactcgctggacctgccgcgccgcctc
cagatcgagttctcccaggtcatccagaagttcaccgacgccgagggcggcgagttcgcc
gccgggcgcatctgggagatcttctcgcagacctacctggccgagggcggaccggtcgcg
gtgctggcgcaccgctccaccaccgacagcgacggcacctaccggatcgaggccgacgcc
cgggtcaacggcgagatccgcgagctgaccggcaccggcaacggccccatctccgcgttc
tgcgacgccctgaccgacgtcgacgtcaaggtccgcgtcatggactacgtggagcactcc
atgggcggggacggcgacgcccgcgccgccgcctacgtggaggccgagatcgacggccgc
gtggtgtggggcgtgggcatccacagcagcatcaccacggcctcgctcaaggcgctgtgc
agcgccatcgcgcgcgtctga
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