Nocardioides sp. LMS-CY: KM427_11080
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Entry
KM427_11080 CDS
T10875
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nocl Nocardioides sp. LMS-CY
Pathway
nocl00300
Lysine biosynthesis
nocl00550
Peptidoglycan biosynthesis
nocl01100
Metabolic pathways
nocl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nocl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
KM427_11080
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
KM427_11080
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
KM427_11080
Enzymes [BR:
nocl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
KM427_11080
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Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
DUF6707
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QWF24178
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Position
2286537..2287925
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AA seq
462 aa
AA seq
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MLALSLREIADIVGGSVTADVADVVVSGPAYVDSRRPQPGGLFVAVVGERVDGHEYAAGA
HAVLGTRPTEAPTVVVADPVVALGRLARHVVDRLVAGGTTVLALTGSQGKTGTKDYLAQV
LAAAGPTVATAGNHNNEIGVPLTVLTADAATRYLVVEMGARGVGHIAYLCEIAPPQVAAV
LNVGTAHIGEFGSRDAIAAAKGEIVEALPPSGTAVLNADDPLVAAMATRTAAAVLTFGAE
HADATVRASDVDLDDLGRPEVTLAVGGQRTRLRLPHSGLHQVENAAAAAAMALAAGVDLA
VIGPALEAAATASPMRMELHERSDGLLVINDAYNANPASMTAAVETLAEIGARRGRRTVA
VLGEMRELGDQAHAGHVEVGRAAAALGVGVVVVVGAPAAGIADGLRGVPEWAGEVIVTAG
RDEAAAWVRENVAGADVVLVKASRGAALETIADGLLEGDHKP
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
gtgcttgccctgagcctgcgcgagatcgcggacatcgtgggcggctcggtcaccgcggac
gtcgccgatgtcgtggtgagcggacctgcctacgtcgacagccgccggccgcagccgggc
ggtctcttcgtggcggtggtcggcgagcgggtcgacggccacgagtacgccgccggggcg
cacgccgtcctcggcacccggccgaccgaggcgccgacggtcgtggtcgccgaccccgtc
gtcgcgctcgggcgcctcgcgcgccacgtcgtcgaccggctcgtcgccggcgggaccacc
gtgctcgcgctgaccggctcgcagggcaagaccggcaccaaggactacctcgcccaggtg
ctcgccgccgccggtccgaccgtggcgaccgccggcaaccacaacaacgagatcggcgtc
ccactgaccgtgctcaccgccgacgccgccacgcgctacctcgtcgtcgagatgggcgcc
cgcggcgtcggtcacatcgcctacctgtgcgagatcgcgccgccgcaggtcgccgccgtg
ctcaacgtcggcaccgcgcacatcggggagttcggctcgcgtgatgcgatcgccgccgcc
aagggcgagatcgtcgaggcgctgccgccctcgggcaccgcggtgctgaacgccgacgac
ccgctcgtggccgcgatggccacgcgcacggcggccgcggtcctcaccttcggggccgag
cacgccgacgcgaccgtacgcgcctccgacgtcgacctcgacgacctcggccggcccgag
gtcaccctggcggtcggcgggcagcgcacccggctgcggctcccgcacagcggtctccac
caggtcgagaacgccgcggccgccgcggcgatggcgctggcggccggggtcgacctcgcg
gtcatcgggcccgcgctcgaggccgccgcgaccgcgtccccgatgcgcatggagctgcac
gagcggtccgacgggctgctggtgatcaacgacgcctacaacgccaacccggcctcgatg
acggccgccgtcgagacgctggccgagatcggcgcgcgccgcggacgtcgtaccgtcgcc
gtcctcggcgagatgcgcgagctcggcgaccaggcacacgccggccacgtcgaggtcggc
cgggccgcggccgcgctcggcgtcggcgtcgtggtcgtggtcggcgctccggccgcgggc
atcgccgacgggctgcgcggcgtaccggagtgggccggtgaggtgatcgtcacggcgggg
cgcgacgaggcggcggcctgggtgcgcgagaatgtcgcgggcgccgatgtcgtgctggtc
aaggcctcgcgcggagccgccctggagacgatcgccgacggcctgctggagggagaccac
aagccatga
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