KEGG   PATHWAY: npd04136
Entry
npd04136                    Pathway                                
Name
Autophagy - other - Nothoprocta perdicaria (Chilean tinamou)
Description
Autophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either in a housekeeping capacity or during stress and senescence. The process of autophagy could be divided into several stages: induction, vesicle nucleation, elongation and closure, and fusion and digestion. Most essential autophagic machineries are conserved throughout eukaryotes (see map04140 for animals and map04138 for fungi). This map is for other eukaryotes including plants and protists, where autophagy related genes (ATGs) play similar roles in the life cycle. However, autophagy has been relatively less studied in lower eukaryotes.
Class
Cellular Processes; Transport and catabolism
Pathway map
npd04136  Autophagy - other
npd04136

Other DBs
GO: 0006914
Organism
Nothoprocta perdicaria (Chilean tinamou) [GN:npd]
Gene
112942313  IGBP1; immunoglobulin-binding protein 1 [KO:K17606]
112943807  ATG13; autophagy-related protein 13 isoform X1 [KO:K08331]
112944506  ATG4A; cysteine protease ATG4A [KO:K08342] [EC:3.4.22.-]
112944833  ATG4B; cysteine protease ATG4B [KO:K08342] [EC:3.4.22.-]
112945119  ATG5; autophagy protein 5 isoform X1 [KO:K08339]
112945291  RPTOR; regulatory-associated protein of mTOR [KO:K07204]
112946408  ATG10; ubiquitin-like-conjugating enzyme ATG10 [KO:K17888]
112947417  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
112947476  GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2 [KO:K08341]
112948475  ATG4C; cysteine protease ATG4C [KO:K08342] [EC:3.4.22.-]
112949225  ATG16L1; autophagy-related protein 16-1 isoform X1 [KO:K17890]
112950298  ATG101; autophagy-related protein 101 [KO:K19730]
112951689  ATG3; ubiquitin-like-conjugating enzyme ATG3 [KO:K08343]
112951797  BECN1; beclin-1 [KO:K08334]
112952396  PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform [KO:K04382] [EC:3.1.3.16]
112952622  PIK3R4; phosphoinositide 3-kinase regulatory subunit 4 [KO:K08333] [EC:2.7.11.1]
112953077  ATG7; ubiquitin-like modifier-activating enzyme ATG7 isoform X1 [KO:K08337]
112953464  PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform [KO:K04382] [EC:3.1.3.16]
112953632  WIPI1; WD repeat domain phosphoinositide-interacting protein 1 [KO:K17908]
112954702  ULK2; serine/threonine-protein kinase ULK2 isoform X1 [KO:K08269] [EC:2.7.11.1]
112955779  [KO:K08341]
112956932  ATG2B; autophagy-related protein 2 homolog B isoform X1 [KO:K17906]
112958909  ATG12; ubiquitin-like protein ATG12 [KO:K08336]
112959109  [KO:K17907]
112959567  MTOR; serine/threonine-protein kinase mTOR isoform X1 [KO:K07203] [EC:2.7.11.1]
112959593  ATG9A; autophagy-related protein 9A [KO:K17907]
112959770  WIPI2; WD repeat domain phosphoinositide-interacting protein 2 isoform X1 [KO:K17908]
112959904  MLST8; target of rapamycin complex subunit LST8 isoform X1 [KO:K08266]
Compound
C00350  Phosphatidylethanolamine
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
Reference
  Authors
Duszenko M, Ginger ML, Brennand A, Gualdron-Lopez M, Colombo MI, Coombs GH, Coppens I, Jayabalasingham B, Langsley G, de Castro SL, Menna-Barreto R, Mottram JC, Navarro M, Rigden DJ, Romano PS, Stoka V, Turk B, Michels PA
  Title
Autophagy in protists.
  Journal
Autophagy 7:127-58 (2011)
DOI:10.4161/auto.7.2.13310
Reference
  Authors
Avin-Wittenberg T, Honig A, Galili G
  Title
Variations on a theme: plant autophagy in comparison to yeast and mammals.
  Journal
Protoplasma 249:285-99 (2012)
DOI:10.1007/s00709-011-0296-z
Reference
  Authors
Liu Y, Bassham DC
  Title
Autophagy: pathways for self-eating in plant cells.
  Journal
Annu Rev Plant Biol 63:215-37 (2012)
DOI:10.1146/annurev-arplant-042811-105441
Reference
  Authors
Yoshimoto K
  Title
Beginning to understand autophagy, an intracellular self-degradation system in plants.
  Journal
Plant Cell Physiol 53:1355-65 (2012)
DOI:10.1093/pcp/pcs099
Reference
  Authors
Li F, Chung T, Vierstra RD
  Title
AUTOPHAGY-RELATED11 plays a critical role in general autophagy- and senescence-induced mitophagy in Arabidopsis.
  Journal
Plant Cell 26:788-807 (2014)
DOI:10.1105/tpc.113.120014
Reference
  Authors
Michaeli S, Galili G, Genschik P, Fernie AR, Avin-Wittenberg T
  Title
Autophagy in Plants--What's New on the Menu?
  Journal
Trends Plant Sci 21:134-44 (2016)
DOI:10.1016/j.tplants.2015.10.008
Reference
  Authors
Yang X, Bassham DC
  Title
New Insight into the Mechanism and Function of Autophagy in Plant Cells.
  Journal
Int Rev Cell Mol Biol 320:1-40 (2015)
DOI:10.1016/bs.ircmb.2015.07.005
KO pathway
ko04136   

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