Nyctereutes procyonoides (raccoon dog): 129494612 Help Entry 129494612         CDS       T09008                                  Symbol PRKCA Name (RefSeq) protein kinase C alpha type   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism npo  Nyctereutes procyonoides (raccoon dog) Pathway npo01521   EGFR tyrosine kinase inhibitor resistance npo04010   MAPK signaling pathway npo04012   ErbB signaling pathway npo04014   Ras signaling pathway npo04015   Rap1 signaling pathway npo04020   Calcium signaling pathway npo04066   HIF-1 signaling pathway npo04070   Phosphatidylinositol signaling system npo04071   Sphingolipid signaling pathway npo04072   Phospholipase D signaling pathway npo04082   Neuroactive ligand signaling npo04150   mTOR signaling pathway npo04151   PI3K-Akt signaling pathway npo04261   Adrenergic signaling in cardiomyocytes npo04270   Vascular smooth muscle contraction npo04310   Wnt signaling pathway npo04360   Axon guidance npo04370   VEGF signaling pathway npo04510   Focal adhesion npo04540   Gap junction npo04613   Neutrophil extracellular trap formation npo04650   Natural killer cell mediated cytotoxicity npo04664   Fc epsilon RI signaling pathway npo04666   Fc gamma R-mediated phagocytosis npo04670   Leukocyte transendothelial migration npo04713   Circadian entrainment npo04720   Long-term potentiation npo04723   Retrograde endocannabinoid signaling npo04724   Glutamatergic synapse npo04725   Cholinergic synapse npo04726   Serotonergic synapse npo04727   GABAergic synapse npo04728   Dopaminergic synapse npo04730   Long-term depression npo04750   Inflammatory mediator regulation of TRP channels npo04911   Insulin secretion npo04912   GnRH signaling pathway npo04916   Melanogenesis npo04918   Thyroid hormone synthesis npo04919   Thyroid hormone signaling pathway npo04921   Oxytocin signaling pathway npo04925   Aldosterone synthesis and secretion npo04926   Relaxin signaling pathway npo04928   Parathyroid hormone synthesis, secretion and action npo04929   GnRH secretion npo04933   AGE-RAGE signaling pathway in diabetic complications npo04935   Growth hormone synthesis, secretion and action npo04960   Aldosterone-regulated sodium reabsorption npo04961   Endocrine and other factor-regulated calcium reabsorption npo04970   Salivary secretion npo04971   Gastric acid secretion npo04972   Pancreatic secretion npo05017   Spinocerebellar ataxia npo05022   Pathways of neurodegeneration - multiple diseases npo05031   Amphetamine addiction npo05032   Morphine addiction npo05143   African trypanosomiasis npo05146   Amoebiasis npo05161   Hepatitis B npo05163   Human cytomegalovirus infection npo05164   Influenza A npo05170   Human immunodeficiency virus 1 infection npo05171   Coronavirus disease - COVID-19 npo05200   Pathways in cancer npo05205   Proteoglycans in cancer npo05206   MicroRNAs in cancer npo05207   Chemical carcinogenesis - receptor activation npo05214   Glioma npo05223   Non-small cell lung cancer npo05225   Hepatocellular carcinoma npo05231   Choline metabolism in cancer npo05415   Diabetic cardiomyopathy npo05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:npo00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     129494612 (PRKCA)    04012 ErbB signaling pathway     129494612 (PRKCA)    04014 Ras signaling pathway     129494612 (PRKCA)    04015 Rap1 signaling pathway     129494612 (PRKCA)    04310 Wnt signaling pathway     129494612 (PRKCA)    04370 VEGF signaling pathway     129494612 (PRKCA)    04066 HIF-1 signaling pathway     129494612 (PRKCA)    04020 Calcium signaling pathway     129494612 (PRKCA)    04070 Phosphatidylinositol signaling system     129494612 (PRKCA)    04072 Phospholipase D signaling pathway     129494612 (PRKCA)    04071 Sphingolipid signaling pathway     129494612 (PRKCA)    04151 PI3K-Akt signaling pathway     129494612 (PRKCA)    04150 mTOR signaling pathway     129494612 (PRKCA)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     129494612 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     129494612 (PRKCA)    04540 Gap junction     129494612 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     129494612 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     129494612 (PRKCA)    04664 Fc epsilon RI signaling pathway     129494612 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     129494612 (PRKCA)    04670 Leukocyte transendothelial migration     129494612 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     129494612 (PRKCA)    04929 GnRH secretion     129494612 (PRKCA)    04912 GnRH signaling pathway     129494612 (PRKCA)    04921 Oxytocin signaling pathway     129494612 (PRKCA)    04926 Relaxin signaling pathway     129494612 (PRKCA)    04935 Growth hormone synthesis, secretion and action     129494612 (PRKCA)    04918 Thyroid hormone synthesis     129494612 (PRKCA)    04919 Thyroid hormone signaling pathway     129494612 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     129494612 (PRKCA)    04916 Melanogenesis     129494612 (PRKCA)    04925 Aldosterone synthesis and secretion     129494612 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     129494612 (PRKCA)    04270 Vascular smooth muscle contraction     129494612 (PRKCA)   09154 Digestive system    04970 Salivary secretion     129494612 (PRKCA)    04971 Gastric acid secretion     129494612 (PRKCA)    04972 Pancreatic secretion     129494612 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     129494612 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     129494612 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     129494612 (PRKCA)    04727 GABAergic synapse     129494612 (PRKCA)    04725 Cholinergic synapse     129494612 (PRKCA)    04728 Dopaminergic synapse     129494612 (PRKCA)    04726 Serotonergic synapse     129494612 (PRKCA)    04720 Long-term potentiation     129494612 (PRKCA)    04730 Long-term depression     129494612 (PRKCA)    04723 Retrograde endocannabinoid signaling     129494612 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     129494612 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     129494612 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     129494612 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     129494612 (PRKCA)    05206 MicroRNAs in cancer     129494612 (PRKCA)    05205 Proteoglycans in cancer     129494612 (PRKCA)    05207 Chemical carcinogenesis - receptor activation     129494612 (PRKCA)    05231 Choline metabolism in cancer     129494612 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     129494612 (PRKCA)    05214 Glioma     129494612 (PRKCA)    05223 Non-small cell lung cancer     129494612 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     129494612 (PRKCA)    05161 Hepatitis B     129494612 (PRKCA)    05171 Coronavirus disease - COVID-19     129494612 (PRKCA)    05164 Influenza A     129494612 (PRKCA)    05163 Human cytomegalovirus infection     129494612 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     129494612 (PRKCA)    05143 African trypanosomiasis     129494612 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     129494612 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     129494612 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     129494612 (PRKCA)    05032 Morphine addiction     129494612 (PRKCA)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     129494612 (PRKCA)    05415 Diabetic cardiomyopathy     129494612 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     129494612 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     129494612 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:npo01001]     129494612 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:npo04131]     129494612 (PRKCA) Enzymes [BR:npo01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      129494612 (PRKCA) Protein kinases [BR:npo01001]  Serine/threonine kinases: AGC group   PKC family [OT]    129494612 (PRKCA) Membrane trafficking [BR:npo04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     129494612 (PRKCA) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 ABC1 Motif Other DBs NCBI-GeneID:  129494612 NCBI-ProteinID:  XP_055157515 LinkDB All DBs Position Unknown AA seq 672 aa AA seqDB search MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVE LRQKFEKAKLGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRI DWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN PQFVHPILQSAV NT seq 2019 nt NT seq  +upstreamnt  +downstreamnt atggctgacgttttcccggccaacgactccacggcgtctcaggacgtggccaaccgcttc gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt gggaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa tttgtcactttttcttgtccgggtgcggataagggacccgacactgatgaccccagaagc aagcacaagtttaaaatccacacttatggaagccccaccttctgtgatcactgtgggtca ttgctgtatggacttatccatcaaggaatgaaatgtgacacctgtgatatgaacgtgcac aagcagtgtgtaataaatgtccccagcctctgcgggatggaccacacggagaagaggggc cggatctacctgaaggctgaggtcactgatgagaagctccatgtcactgtacgagatgca aagaatctgattcctatggatccaaatgggctttcagatccttatgtgaagctgaaacta attcctgatcccaagaatgaaagcaaacagaaaaccaaaaccatccgctctacactgaat ccccagtggaatgagtcttttacattcaaattaaaaccttcagataaagaccgccggctg tccgtagagatctgggactgggatcgaacaacaaggaatgatttcatgggctccctttct ttcggagtctcagagctgatgaagatgccagccagtggatggtacaagctgcttaaccaa gaggaaggtgagtactacaatgtacccatcccagaaggggacgaagaaggaaacgtggag ctcagacagaaattcgagaaagccaagcttggccccgctggtaacaaagtaatcagtcct tcagaagacaggagacaaccttccaacaacctggacagagtgaaactcacagacttcaat ttcctcatggtgctggggaagggaagttttggaaaggtaatgcttgctgacaggaagggc acagaggaactgtatgctatcaaaatcctgaagaaggacgtggtgattcaagatgacgac gtggagtgcaccatggtggagaagcgagtcctggccctgcttgacaagcccccattcctg acacagctacactcctgcttccagacagtggatcgactgtacttcgtcatggaatacgtc aatggtggggacctcatgtaccacattcagcaagtaggaaaatttaaggaaccacaagca gtattttatgcggcagagatttccattggattgttctttcttcataaaagaggaatcatt tacagggatctgaagttagacaatgtcatgctggattcggaagggcatatcaagattgct gattttgggatgtgcaaggaacacatgatggatggagtcacaaccaggaccttctgcggg actccagattacattgccccggagataatcgcttatcagccgtatggaaaatccgtggac tggtgggcctatggcgtcctattatatgaaatgctagccggacagcctccctttgatggt gaagatgaagacgagctgtttcagtccataatggagcataacgtttcttatcccaaatcc ttgtccaaagaggccgtttccatctgcaaaggactgatgaccaaacacccaggcaagcgg ctgggttgtgggccagagggagagagagacgttcgggagcatgccttcttccggaggatc gactgggaaaaactcgagaacagggagatccagccacccttcaagcccaaagtgtgtggc aaaggcgcagaaaactttgacaagttcttcacacgagggcagcctgtcttaacaccacct gatcagttggtcattgctaacatagaccagtctgatttcgaggggttctcgtatgtcaac ccccaatttgtgcaccccatcttacagagtgcggtatga

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