Nyctereutes procyonoides (raccoon dog): 129497753
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Entry
129497753 CDS
T09008
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
npo
Nyctereutes procyonoides (raccoon dog)
Pathway
npo00562
Inositol phosphate metabolism
npo01100
Metabolic pathways
npo01521
EGFR tyrosine kinase inhibitor resistance
npo04012
ErbB signaling pathway
npo04014
Ras signaling pathway
npo04020
Calcium signaling pathway
npo04062
Chemokine signaling pathway
npo04064
NF-kappa B signaling pathway
npo04066
HIF-1 signaling pathway
npo04070
Phosphatidylinositol signaling system
npo04072
Phospholipase D signaling pathway
npo04360
Axon guidance
npo04370
VEGF signaling pathway
npo04380
Osteoclast differentiation
npo04517
IgSF CAM signaling
npo04611
Platelet activation
npo04613
Neutrophil extracellular trap formation
npo04625
C-type lectin receptor signaling pathway
npo04650
Natural killer cell mediated cytotoxicity
npo04662
B cell receptor signaling pathway
npo04664
Fc epsilon RI signaling pathway
npo04666
Fc gamma R-mediated phagocytosis
npo04670
Leukocyte transendothelial migration
npo04722
Neurotrophin signaling pathway
npo04750
Inflammatory mediator regulation of TRP channels
npo04919
Thyroid hormone signaling pathway
npo04933
AGE-RAGE signaling pathway in diabetic complications
npo04935
Growth hormone synthesis, secretion and action
npo05167
Kaposi sarcoma-associated herpesvirus infection
npo05169
Epstein-Barr virus infection
npo05170
Human immunodeficiency virus 1 infection
npo05171
Coronavirus disease - COVID-19
npo05200
Pathways in cancer
npo05205
Proteoglycans in cancer
npo05206
MicroRNAs in cancer
npo05214
Glioma
npo05223
Non-small cell lung cancer
npo05225
Hepatocellular carcinoma
Module
npo_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
npo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
129497753 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
129497753 (PLCG2)
04014 Ras signaling pathway
129497753 (PLCG2)
04370 VEGF signaling pathway
129497753 (PLCG2)
04064 NF-kappa B signaling pathway
129497753 (PLCG2)
04066 HIF-1 signaling pathway
129497753 (PLCG2)
04020 Calcium signaling pathway
129497753 (PLCG2)
04070 Phosphatidylinositol signaling system
129497753 (PLCG2)
04072 Phospholipase D signaling pathway
129497753 (PLCG2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
129497753 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
129497753 (PLCG2)
04613 Neutrophil extracellular trap formation
129497753 (PLCG2)
04625 C-type lectin receptor signaling pathway
129497753 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
129497753 (PLCG2)
04662 B cell receptor signaling pathway
129497753 (PLCG2)
04664 Fc epsilon RI signaling pathway
129497753 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
129497753 (PLCG2)
04670 Leukocyte transendothelial migration
129497753 (PLCG2)
04062 Chemokine signaling pathway
129497753 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
129497753 (PLCG2)
04919 Thyroid hormone signaling pathway
129497753 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
129497753 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
129497753 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
129497753 (PLCG2)
04380 Osteoclast differentiation
129497753 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129497753 (PLCG2)
05206 MicroRNAs in cancer
129497753 (PLCG2)
05205 Proteoglycans in cancer
129497753 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
129497753 (PLCG2)
05214 Glioma
129497753 (PLCG2)
05223 Non-small cell lung cancer
129497753 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
129497753 (PLCG2)
05171 Coronavirus disease - COVID-19
129497753 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
129497753 (PLCG2)
05169 Epstein-Barr virus infection
129497753 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
129497753 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129497753 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
npo04131
]
129497753 (PLCG2)
Enzymes [BR:
npo01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
129497753 (PLCG2)
Membrane trafficking [BR:
npo04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
129497753 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
129497753 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF_HAND_2_PLCG
C2
SH3_1
PH
SH3_9
PH_12
EF_HAND_1_PLCG
SH2_1
PH_14
SH3_2
GDPD
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
129497753
NCBI-ProteinID:
XP_055162843
LinkDB
All DBs
Position
Unknown
AA seq
1286 aa
AA seq
DB search
MIPAPPSPASSSLTAPPILPTMTALVHVDSLPEYEKSQIKRALELGTVMTVFSFRKSTPE
RRTVQVIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEECCFTIL
YGTQFVLSTLSLAADSKEDANKWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRN
SISLRELKTILPLVNFKVNSAKFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILD
EFKKDSSVFILGNTDRPDASAVHLHDFQRFLLHEQQELWAQDLNKVRARMTKFIDDTMRE
TAEPFLFVDEFLTYLFSRENSIWDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSE
SSTEAYIRCLRMGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSF
PVILSIEEHCCVEQQRHMARVFKEVFGDQLLTKPTEASADQLPSPSQLREKIIIKHKKLG
PRGDVDVNMEDKKDEHKQQGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTAEEELPQ
DTPPTELHFGEEWFHKKVEKRTSAEKLLQEYCAETGGKDGTFLVRESKTFPNDYTLSFWR
SGRVQHCRIRSTVEGGTMKYFLTDNVMFTSIYALIQHYRETHLRCAEFELRLTDPVPNPN
PHESKPWYYDGLSRGEAEDMLMRVPRDGAFLIRRREGTDSYAITFRARGKVKHCRIHRDG
RHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMY
VDPSEINPSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPWGWWKGDYGTRIQQYF
PSNYVEDISTVDVEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPK
KQGDPPVEFATDKVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKP
TSKTKDNLENPDFREIRSFVETKADSVIRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDP
FRLWLCGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKI
LMTLSVKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWAPTQEK
VTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELAS
LLVFCEMQPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNE
NQLQLYQEKCNRRLREKRVSNSRFYS
NT seq
3861 nt
NT seq
+upstream
nt +downstream
nt
atgatccccgctccgccctccccagcgtcctcttccctcactgctccccccattctgcca
acaatgactgccctggtccacgtggacagccttccggaatacgagaagagtcagatcaag
agagccctggagctgggcacagtgatgacggtgttcagcttccgcaagtccaccccagag
cggaggaccgtccaggtgatcatggagacgcgccaggtggcctggagcaagacagccgac
aagatcgagggcttcttggatatcatggaaatcaaggaaatccgcccagggaagaactct
aaggattttgagcgtgcaaaagcagtccgccagaaggaagagtgctgttttaccatcttg
tacggcacccagtttgttctgagcacactcagtctggcagctgactctaaagaagatgcg
aataagtggctctctggcttgaaaatcttacaccaggaagcgatgagtgcatctacaccc
accattattgagagttggctgagaaagcagatttattcagtggaccaaaccagaagaaac
agcatcagcctccgagagttgaagaccatcttacccctggtcaactttaaggtgaacagt
gccaagttcctcaaagataagtttgtggaaattggtgcacacaaagatgagctcagcttt
gagcagttccacctgttctataaaaaacttatgtttgagcagcaaaagtcgattcttgat
gaattcaaaaaagattcttccgtgttcatcttgggcaacactgaccggccggacgcctct
gctgttcacctgcatgacttccagcgctttctcttacatgagcaacaggagctttgggct
caggatctgaacaaagtccgtgcgcggatgacaaagtttatcgatgacaccatgagggaa
acggccgagcccttcttgtttgtcgatgagttcctcacgtatctgttttcgcgggagaac
agcatctgggatgagaagtatgacgtggtggacatgcaggacatgaacaaccccttgtcc
cattactggatctcctcttcgcataacacgtacctcaccggtgaccagctacggagtgag
tcatccacagaagcgtacatccgctgcctgcggatgggctgtcgctgcattgagttggac
tgctgggacggacccgacgggaagcccatcatctaccacggctggacacggaccaccaag
atcaagtttgacgacgttgtgcaggccatcaaagaccatgcctttgtcacttcaagcttc
cccgtgatcctgtccatcgaggagcactgttgcgtggagcagcagcgccacatggccagg
gtgttcaaggaggtgtttggtgaccagctgctgacgaagcccacagaggccagtgctgac
cagctgccctcgcccagccagttgcgggagaagatcatcatcaagcataagaagctgggt
ccccgaggggacgtggatgtcaacatggaggacaagaaagatgagcacaagcaacagggt
gaactgtatatgtgggattccatcgaccagaaatggactcggcactactgtgccatcgcc
gatgccaaactgtctttcagcgatgacattgagcagactgcagaagaggagctgccccag
gacacaccccccacggagctgcattttggggaggagtggttccacaagaaagtagagaag
aggacgagtgccgagaagctgctgcaggaatactgtgcagagacggggggcaaggatggg
actttccttgtgcgggagagcaagaccttccccaatgactacaccctgtccttctggcgg
tccggccgcgtccagcactgccggatccgttccaccgtggaggggggcaccatgaagtac
ttcctgactgacaacgtcatgttcaccagcatctacgccctcatccagcactaccgcgag
acccacctgcgctgcgccgagttcgagctgcggctcaccgaccctgtgcccaaccccaac
ccccacgagtccaagccgtggtactacgacgggctgagccgtggggaggcagaggacatg
ctaatgagggtgccccgggacggcgccttcctgatccggaggcgagaaggtaccgactcc
tatgccatcaccttcagggccaggggcaaggtgaagcactgccgaattcaccgggatggc
cggcactttgtgctggggacctctgcctacttcgagagcctcgtggagctagtcagctac
tacgaaaagcacgcgctctaccgaaaaatgcgactgcgctaccccgtgacgcctgagctc
ctggagcgctacaatatggaaagagatataaactccctctatgacgtcagcagaatgtat
gtggatcccagtgagatcaatccttctatgcctcagagaaccgtgaaagctctgtatgac
tacaaagccaagcgaagcgatgagctgagtttctgccgtggggccctcattcacaacgtc
tcgaaggagccctggggctggtggaagggggactatggaaccagaatccagcagtacttc
ccatccaattacgtcgaggacatttcaacagtcgacgtggaggagctggagaaacagatt
attgaagacaatcccttagggtctctttgtaggggaatactggatctcaatacctataac
gttgtgaaagccccccaggggaaaaaccagaagccattcgtgtttatcctggagcccaag
aagcaaggcgaccccccagtagagtttgccacggacaaggtggaggagctctttgagtgg
tttcagagcatccgggagatcacctggaagatagataccaaggagaacaacatgaagtac
tgggagaagaaccagtccatcgccatcgagctctcggacctggtcgtctactgcaagcca
accagcaagaccaaggacaatttagaaaaccctgacttccgagaaatccggtcctttgtg
gagacaaaggcagacagtgtcatcagacagaaacccgttgacctcctgaagtacaatcag
aagggcctgacccgtgtttacccgaaaggacagagggtggactcctccaactacgaccca
tttcgcctctggctgtgcggctcccagatggtggcactcaatttccagactccagacaag
tatatgcagatgaatcacgccttgttctcactcaatgggcgaacgggctacgtcctacag
cctgagagcatgaggacggagaagtatgaccccatgccacctgagtcccagaggaagatc
ctgatgactctgtcagtcaaggttcttggggctcgccatctccccaaacttggacgaagt
atcgcatgtccctttgtggaggtggaaatttgtggagctgaatatgacaacaacaagttt
aagacaacagtcgtgaatgacaatggcctaagccctgtttgggctccaacacaggagaaa
gtgacctttgaaatttacgaccccaacctggcgtttctgcgctttgtggtctacgaggaa
gatatgttcagtgaccccaatttccttgctcacgccacttaccccatcaaaggaatcaaa
tcaggattcagatctgttcctctgaagaacgggtacagtgaagacattgagctggcttcc
ctcttggttttctgtgagatgcagccagtcctggagagcgaagaggaactttattcctcc
tgtcgccagctgcgaaggcggcaggaagagctcaacaatcagctctttctgtacgacaca
caccagaacttgcgcaacgccaaccgggatgccctcgttaaagagttcaatgtcaacgag
aaccagctccagctgtaccaggagaagtgcaaccggaggttgagagagaagcgagtcagc
aacagcaggttttactcctag
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integrated database retrieval system
