Nyctereutes procyonoides (raccoon dog): 129502188
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Entry
129502188 CDS
T09008
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
npo
Nyctereutes procyonoides (raccoon dog)
Pathway
npo00230
Purine metabolism
npo00670
One carbon pool by folate
npo01100
Metabolic pathways
npo01523
Antifolate resistance
Module
npo_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
npo00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
129502188 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
129502188 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
129502188 (GART)
Enzymes [BR:
npo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
129502188 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
129502188 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
129502188 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_3
Dala_Dala_lig_C
ATP-grasp_4
Sacchrp_dh_NADP
RimK
Motif
Other DBs
NCBI-GeneID:
129502188
NCBI-ProteinID:
XP_055169665
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSNHVKHVLVAPGNAGTACLEKISNTAISISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIAGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWKAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSTEEACRAVQEIMQDKAF
GAAGETIVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDHGPNTGGMGAYCPAP
QVSKDLFLKIKNTILQRTVDGMQQEGMPYTGVLYAGIMLTKEGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLDNRAAITVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFHAGTALKDGKVVTNGGRVLTVTAIQENLLLALEEAKKGLSAIKFEGAFYRKD
IGYRAIAFFQQPRGLTYKESGVDIAAGNMLVQKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFRDPLLACGTDGVGTKLKIAQQCDKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLDTTEAVVTGIARACRKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQSWRVPRIFSWLQQEG
HLSEEEMARTFNCGVGAALVVSKDLTEQILKDIKQHKEEAWAIGKVVACPEGSPRVKVRH
LIETMQINGSVLENGTLKNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSCAHIVVV
ISNKAAVAGLDKAERAGIPTRVINHKLYKSRVEFDTAIDQVLEEYSTDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQALEAGVTVTGCTVHFVAEDVDAGQIILQES
VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGAIRLGENGKIRWVTED
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtaatcggcagtggaggaagggagcataccctggcctggaaa
cttgcacagtctaatcatgtcaaacatgtgttggttgccccaggaaatgcaggcactgcc
tgcttggaaaagatttcaaataccgccatctccatcagtgaccacactgcccttgctcag
ttctgcaaagatgagaaaattgaattcgtggttgttggaccagaggcacctctggctgct
ggaatcgctgggaacctgacatctgcaggagtgcgatgctttggtcccactgcagaagca
gctcaattagagtccagcaagagatttgccaaagagtttatggaccgacatggaatccca
actgcacggtggaaagctttcaccaaacctgaagaggcctgcagctttataatgagtgca
gacttccctgctttggttgtaaaggccagtggtcttgcagctggaaaaggggtgattgtt
gccaagagcacagaagaggcctgcagggctgtacaggagattatgcaggataaagctttt
ggagcagctggagaaacaattgtcatcgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggaaggactgtggcccccatgcccccagcacaagaccataagcga
ttgctggaaggagatcatggccccaacacagggggaatgggggcctattgtccagcacct
caggtttctaaggatttgttcctgaaaataaaaaacaccattcttcagagaacagtggat
ggcatgcagcaggagggcatgccatacacaggtgttctctacgctggtataatgctgacc
aaggagggcccaaaagttctggagtttaattgccgttttggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtgattcagtctaccttggatggcctg
ctctgcacatccctgcctgtttggcttgataaccgtgctgccataactgtggtaatggca
agtaaaggctatccaggagattacaccaagggtgtggagataacagggtttcctgaggct
caagctttaggactggaggtgttccatgcaggcactgccctgaaagatggcaaagtggtg
actaacgggggtagagtccttacggtaacggcaatccaggaaaatctcctcttggccctt
gaagaagcaaagaaaggactatctgctataaaatttgagggagccttttacaggaaggac
attggctatcgtgccatagccttcttccagcagcccaggggcctgacttacaaagaatct
ggggtagacattgcagctggaaatatgctggtccaaaaaattaaacctttagcaaaagct
acttccagaccaggctgtgatgttgatcttggaggttttgccggtctttttgatttgaaa
gcagctggtttcagagatcctcttctggcatgtggaacagatggtgttggaactaaactg
aagattgcccagcagtgtgataaacatgatactattggtcaagatttggttgcaatgtgt
gtcaatgacattctagcccaaggggctgagccccttttcttcctcgattacttttcctgt
ggaaaacttgacctcgatacaactgaagcagttgtcactggaattgccagagcttgcaga
aaagctggatgtgctctccttggaggtgaaactgcagaaatgcctgacatgtatcctccg
ggagaatatgacctagctggttttgccgttggtgccatggagcgggatcagaaacttcct
cacctggaaagaatcaccgaaggggatgttgttattggaatagcttcatctggtcttcac
agcaatggatttagccttgtcaggaaaattgtagcaaaatcttccctccagtactcgtct
ccagcacccgatggctgtggtgaccagaccttaggggacttacttctaactccaacccga
atctacagccattcgctgttacctgtcctacgttcaggacatgtgaaggcctttgcccat
attactggtggaggattgctagaaaacatccccagagtccttcctcagaaatttggggtg
gatttagatgcccaaagctggagggtccccaggatcttttcatggctacagcaggaagga
cacctctctgaagaagagatggcgagaacatttaactgtggagttggggctgccctcgtg
gtatcaaaggatctgacggagcagattctgaaggatattaagcagcacaaggaagaagcc
tgggcgattggcaaagtggtggcatgtcctgaaggttctcctcgtgtgaaagtcaggcat
ctgatagaaactatgcaaataaatgggtcagtattggagaatggcaccctgaaaaatcat
ttctctgttcaaccaaaaaaggcaagagtggctgtcttaatatctggaacaggatcaaac
ctgcaagctcttatagacagtactagggagcccagtagctgtgcacacattgttgttgtt
atctccaacaaagctgcagtggctggtttagataaagcggaaagagctggaattcccacc
agagtaatcaaccataaattatataaaagtcgtgtagaatttgacactgccattgaccaa
gtccttgaagagtattccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcagaaaatgggatgggaagatgctcaacatccacccctccttgctccct
tcttttaagggttcaaatgcccatgagcaagccctggaagctggggtcacagtcactggg
tgtactgtgcactttgtagctgaagatgtagatgctggacaaattattttacaagaatct
gttccagtgaagagaggtgacactgttgcaactctgtcggaaagagtgaaattagcagag
cataaaatatttcctgcagccctccagctggtagccagtggagctataaggcttggagaa
aatggcaagatccgttgggtcacagaggattga
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