Nyctereutes procyonoides (raccoon dog): 129505565
Help
Entry
129505565 CDS
T09008
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
npo
Nyctereutes procyonoides (raccoon dog)
Pathway
npo05012
Parkinson disease
npo05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
npo00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
129505565 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
129505565 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
npo01001
]
129505565 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
npo04131
]
129505565 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
npo04147
]
129505565 (LRRK2)
Enzymes [BR:
npo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
129505565 (LRRK2)
Protein kinases [BR:
npo01001
]
Serine/threonine kinases: TKL group
LRRK family
129505565 (LRRK2)
Membrane trafficking [BR:
npo04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
129505565 (LRRK2)
Exosome [BR:
npo04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
129505565 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
COR
LRR_4
Ras
LRR_14
LRR_9
WD40_CDC20-Fz
Arf
LRR_13
Beta-prop_RSE1_2nd
Beta-prop_EML_2
LRR_NXF1-5
AAA_22
T2SSE
Ank_2
nSTAND3
Kdo
PduV-EutP
LRR_6
ABC_tran
MMR_HSR1
GTP_EFTU
WD40_WDHD1_1st
WDR55
AAA_7
G-alpha
AAA_16
SRPRB
TniB
TsaE
cobW
MobB
Septin
AAA_29
AAA_23
NACHT
TrwB_AAD_bind
ARM_LIN_2nd
SRP54
Motif
Other DBs
NCBI-GeneID:
129505565
NCBI-ProteinID:
XP_055174598
LinkDB
All DBs
Position
Unknown
AA seq
2527 aa
AA seq
DB search
MASGSCQGCEEEDEETLKKLVVRLNNVQEGKQIETLVQILEDMLVFTYADHASKLFQGKK
VHVPVLIVLDLYMRVASVQQVGWSLLCKLIEICPNTMQSLMGPQDIGHDWEVLGVHQLIL
KMLTVHNASVNLLTVGLRALDLLLTSGKITLLILDEESDIFLLIFDAMRTFSANDEVQKL
GCKALRVLFERVSEEQLIEFVENKDYMILLDALKNFKDEEEIVLHVLHCLHSLAIPCNNV
EVLMSGNVRCYNIVVEAMKAFPVHEKIQEVSCCLLHRLTLGNFFNILVLNEVHEFVVKAV
RRYSENATLQIAALSCLALLTETIFLNQDLEEKNENQENDDEEEGKLFWLEACYKALTWH
RKNKHVQEAACWALNNLLMYQNSLHEKIGDEDGQFPAHREVMLSMLMHSSSKEVFQASAN
ALSTLLEQNVNFRKILLSKGIYFNVLELMQKHIHSPEVAESGCKLLDHLFEGSDATLDIM
AAVAPKIITVMKSHEASSLVQLEALRAILHFIVPGMPEDSREDTEYQHKLNLVKKQCFKN
DIHKLVLAALNRFIGIPGIQKSGLKVISSLAQSPDALEVLSLEGAIDSVLHTLQMYPDDQ
EIQCLGLSLIGCLITKKNLCIGTGHLLAKILASSLQRFKDMAEVQIKGFQTILTILELSM
SFGKLLVHHSFDSVIFHQMSSSILESKDQQFLNLCCKCFAKLAMDDELKSVMLERACDQN
NSIMVECLLLLGADANRTKEATSLICQVCEKASSPKLVELLLNGGSREQDVRKALTISIG
KGDSQIISLLLRRLALDLANNSICLGGFCIGKIEPSWLGPLFPDKTSNLRKETNIGSTLA
RMVLRYQMKSTVEGGAASGSNGNFPEEVLDKLDEWTFVPDSYVDSVFGQSDDLDSEGSEG
SFLVKRKSNSISVGEFYHDRALQRCSPNLQRHSNSLGPIFDHEDFLRRKRKILSSDDPLW
SSKLQSHMRHSDSISSLPSEREYITSLDLSANELRDIDALSQKCCISGHLEHLEKLELHQ
NALTSFPQQLCETLKCLTHLDLHSNKFASFPSYLLKMNCIVNLDVSRNDISPSVVLDPTV
KCPTLKQFNLSYNQLSSFPENLGDVVEQLEQLILEGNKIPGICSPLSLKELKILNLSKNH
ITSLAEDFFEACPKVESFSARINYLAAMPFLPSSLTSLKLSQNRFTCVPEAILNLPHLRS
LDMSSNEIEYLPSPAHWKSLNLRELLFSFNQISILDLSEKAYVWSRVEKLHLSHNKLKEI
PPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELRLNFDFKHIGCKAKDIIR
FLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLTKTKKSDLGVQSATVGIDVKDWPIQI
RGKGKKDLILNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKA
RASSSPVILVGTHLDVSDEKQRKACISKITKELLNKRGFPAIRDYHFVNATEESDALAKL
RKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVKEN
QLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKVMAQILTVKVEGYPK
HPKGIISRRDVEKFLSKKKRFPKNYMSQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVI
ELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIYL
NWSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDI
CGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDLI
LADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLLRQE
LVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVAD
GLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRA
PEVARGNVIYNQQADVYSFGLLLYDILTTGGRIAEGLKFPNEFDELAIQGKLPDPVKEYG
CAPWPMVEKLIKKCLKENPQERPTSAQVFDILNSAELICLMRHISIPKNFSVECMVATNH
NSKNASIWLGCGHPSKGQLSFLDLSTEKHTSEEVTDSRILCLALVHLPVEKENWIVCGTQ
SGMLLVINTEDGAKRHTLEKMTDSVTCLYCNPFPKQSKQRNFLLVGTADGNLAIFEDKTV
KCKGAAPLKILNIGNVSTPLMCLSESMNSTEKNIMWGGCGTKLFSFSDDFTIQKLIETKT
NQLFSYAAFSDSNIIAVVVDTAVYVAKKNSPFVEVRDKKTEKLCELIDCVHFLKEEMVKV
NAESKHKLSYSGRVKTLCLQKNTALWIGTGGGHILLLDLSTRRIIRIIHNFCDSVRVMMT
AQLGSLKNVMLVLGYIRKNTEGTQPQKEIQSCLSVWDINLPHEVQNLEKHIEVRKELAEK
MRRISVE
NT seq
7584 nt
NT seq
+upstream
nt +downstream
nt
atggccagtggcagctgtcagggctgcgaggaggaggacgaggaaactctgaagaagttg
gtagtcaggctgaacaatgtccaggaaggaaaacagatagagaccctggtccaaatcctg
gaggatatgctggtgttcacgtacgccgaccacgcctccaagttatttcaaggcaaaaaa
gtccacgtgcctgtgttgatcgtcttggacttgtatatgagagtcgctagtgtgcagcag
gtgggttggtcgcttctttgcaaattgatagaaatctgtccaaatacaatgcaaagctta
atgggacctcaggatattggacatgattgggaagtccttggggttcaccaactgattctt
aaaatgctaacagttcataatgccagtgtaaacctgttaacagttggactgagggcctta
gatctccttctaacttcaggcaaaatcactttgctgatactggatgaagaaagtgatatt
ttcttgttaatttttgatgccatgcgcacattttcagccaatgatgaagtccagaaactt
ggatgcaaagctttacgtgtgctgtttgaaagagtttcagaggagcagttgattgaattt
gttgagaataaagattatatgatcttgctcgatgcattaaaaaattttaaagatgaagag
gaaattgtgcttcatgtactacactgtttacattccctagcaattccttgcaataatgtt
gaagtactcatgagtggcaacgtcaggtgttacaatattgtggtagaagccatgaaagca
ttccctgttcatgaaaaaattcaagaagtgagttgctgcttgctccataggcttacatta
ggtaatttttttaacattctggtattaaacgaggtacatgagttcgtggtgaaagctgtg
aggcggtattcagagaacgccacattacaaattgcagcactcagctgtttagcgctcctc
actgagactattttcttaaatcaagacttagaggaaaagaatgagaatcaggagaatgat
gatgaggaagaaggaaaattgttctggttggaagcctgttacaaagcattaacatggcat
agaaaaaacaagcacgtgcaggaagctgcatgctgggctctaaacaatctccttatgtac
caaaacagtttacatgagaagattggagatgaagatggccagttcccagctcatagggaa
gtgatgctgtccatgctgatgcattcttcatcaaaagaagtcttccaggcatctgcaaat
gcgttgtcaactctattagaacaaaacgttaatttcagaaaaatcctgttgtcaaaagga
atatacttcaatgtattggagttaatgcagaagcatatacattctcctgaagttgctgaa
agtggctgtaaactgctagatcatctctttgaaggaagtgatgctaccctggatataatg
gcagcagtggcccccaaaatcataacagttatgaaaagtcatgaggcatcctcattggtg
cagctggaggcactccgagctattttacattttatagttccaggcatgccagaagattcc
agggaagacactgaatatcaacataagctaaatctggttaagaagcagtgtttcaagaat
gatattcataaactggtcctagcagctttgaacaggttcattggaattcctgggattcaa
aaaagtggattgaaagtaatttcttctctagcacaatctcctgatgcattagaagtatta
tccttggaaggtgctattgattcagtgcttcacacactgcagatgtacccagatgaccaa
gagattcaatgtctggggttaagtcttataggatgcttgattacaaagaagaatttatgc
ataggaactgggcatctgctggcaaaaattctggcttccagtttacaacgatttaaagat
atggctgaagtacagattaaaggatttcagacaatcttgacaatactagaattgtcaatg
tcttttggaaagctgctggtgcatcattcatttgattctgtgatattccatcagatgtct
tccagtatccttgaatcaaaggatcaacagtttctaaacctttgttgcaagtgctttgcg
aaattagctatggatgatgagttaaaaagtgtgatgctagagagagcatgcgatcagaat
aacagtatcatggttgaatgcttgcttctgttgggagcggacgccaatcgaacaaaggaa
gcaacatctttaatttgtcaggtatgtgagaaagcgagcagtcccaaattggtggaactg
ttattgaatggtggttcccgtgaacaagatgttcggaaagccttgacaataagcattgga
aaaggtgacagccaaatcatcagcttactcttaaggagacttgccctggatctggccaat
aatagcatttgccttggaggattttgtataggaaaaatcgaaccttcgtggcttggtcct
ttatttccggataagacatctaatttaagaaaagaaacaaatataggatccaccctagca
agaatggtgctcagatatcagatgaaaagtactgtggaaggaggggcagcctcaggcagc
aatggaaattttcctgaagaagtacttgacaaattggatgaatggaccttcgttccagac
tcttacgtggacagtgtgtttggtcaaagtgatgacctggatagtgaaggaagtgaaggt
tcatttcttgtgaaaagaaaatccaattcaattagtgtaggagaattttaccatgatcgt
gccttgcagcgttgctcaccaaatttgcaaaggcattccaattcattgggacccattttc
gatcatgaagatttcctgaggcgaaaaagaaaaatattgtcttcagatgacccactctgg
tcatcaaaacttcaatcccatatgagacattcagacagcatttcttccttgccttctgag
agagaatatattacatcattggacctttcagcaaatgaactaagagatattgatgcccta
agccagaaatgctgtataagtggtcatttggaacatcttgaaaagctggagcttcaccag
aatgcacttacaagctttccacaacaactgtgtgaaacgctgaagtgtttgacccatttg
gacttgcacagtaataaatttgcatcatttccctcttacctgttgaaaatgaattgtatt
gtcaaccttgatgtctctcgaaacgacatcagcccctcagtagttctggatcctacagtg
aagtgcccaaccttgaaacagtttaacttgtcatataatcagctgtcttcttttcctgag
aaccttggcgatgtggtagagcaattggaacagctcattttagaaggaaataagatacca
ggaatatgttcccccttaagcctgaaggaactgaagattttaaaccttagtaaaaaccac
attacatccctagcagaggacttctttgaggcatgtcctaaagtggagagtttcagtgcc
agaattaattatcttgctgctatgccttttttgccttcttctctgacaagcctaaaatta
tctcaaaacagatttacatgtgttccagaagcaattttaaatcttccacacttgcgatcc
ttagatatgagcagcaatgaaattgagtatctaccgagtcctgcacactggaaatctttg
aacttaagggaactcttgttcagttttaatcagatcagcatcttggacttgagtgaaaaa
gcttatgtgtggtcaagagtagagaaactacatctttctcataataaactgaaggagatt
cctccagagattggctgtcttgaaaacctgacctcccttgatgtcagttacaatttggaa
ctgagatcctttcctaatgaaatggggaaattaagcaaaatatgggaccttcctttggat
gaactacggcttaattttgattttaaacatataggatgtaaagccaaagacatcataagg
tttcttcaacagcggttaaaaaaggctgtgccctataaccgaatgaagcttatgattgtg
ggaaatactgggagtggtaaaactaccttattgcagcaattaacaaaaaccaagaaatca
gatcttggggtgcagagtgccacagttggtatagatgtgaaagactggcctatccaaata
agaggcaaagggaagaaagacctcattctaaatgtgtgggattttgcaggtcgtgaggaa
ttctacagcactcatccccacttcatgacccaacgagccctttaccttgctgtttatgac
ctcagcaaagggcaggctgaagtggatgccatgaagccttggctcttcaatataaaggct
cgtgcttcttcttcccctgtgatcctcgttggcacgcatttggatgtttctgatgaaaag
cagcgtaaagcctgcataagtaaaatcaccaaggaactcttgaacaaacgagggtttcct
gcaataagggattaccactttgtgaatgccactgaggaatctgatgctttggcaaaactt
cggaaaaccatcataaatgagagtcttaattttaagatccgagatcagcctgttgttggg
cagctgattccagactgttatgtagaacttgagaaaatcattttatcagagcgtaaaaat
gtgccaattgaatttcctgtaatcgaccggaaacgattattacaacttgtaaaggaaaat
cagctgcagttggatgaaaatgagctccctcatgcagttcacttcctaaatgaatcaggg
gtccttcttcattttcaagatccagctctgcagttaagtgacttatattttgtggaaccc
aagtggctttgtaaagtcatggcacagattttgacagtgaaagtggaaggctatccaaaa
catcccaagggaatcatttcacgtagagatgtggaaaaatttctttcaaagaaaaagaga
tttccaaagaactacatgtcacagtattttaaactgctagaaaaattccagattgccttg
ccaataggagaagaatatttgctggttccaagcagtttgtctgatcacaggcctgtgata
gagcttccccattgtgagaactctgaaattatcattcgactatacgaaatgccttatttt
ccaatgggattttggtcgaggttaatcaatcgattacttgaaatttcaccttacatgctt
tcaggaagagaacgagcacttcgcccaaacagaatgtattggcgacaaggcatctacttg
aattggtctcctgaagcttattgtctggtaggatctgaagtcttagacaatcacccagag
agtttcttaaaaattacagttccttcttgtagaaaaggctgtattcttttgggccaagtt
gtggatcacattgattctctgatggaagaatggtttcctggattgctggagattgatatt
tgtggtgaaggagaaaccctgttgaagaaatgggcattatatagttttaatgatggtgaa
gagcatcaaaaaatcttacttgacgacttgatgaagaaagcagaagaaggagaccttcta
gtaaatccagatcagccaaggctcaccattccaatatctcaaattgctcctgacttaatt
ttggctgacttacctagaaatattatgttgaataatgatgaattggaatttgaacaagct
ccagagtttctcttaggtgatggcagttttggatctgtttatcgagcagcctatgaagga
gaagaagtggctgtgaagattttcaataaacatacatcacttagactgttaagacaagag
ctggtagtcctttgccacctccaccaccccagcttaatatctttgctggcggctgggatt
cgtcctcgcatgttggtgatggagttggcctccaagggttcgctggaccgcttgcttcag
caggacaaagccagtctcaccagaactctgcagcacagaattgcactacatgtggctgat
ggcttgagatacctccactcagccatgattatataccgtgacttgaagccccacaatgtg
ttgctcttcaccctgtaccccaatgctgccatcatcgcaaagattgctgactacgggatt
gctcagtactgctgtagaatggggataaagacgtcagagggcacaccaggatttcgtgca
cctgaagttgctagaggaaacgttatttataaccaacaggctgatgtttattcatttggt
ttactactctatgacattttgacaactggaggtagaatagcagagggtttgaagtttcca
aatgagtttgatgaactggcaatacaaggaaaattacctgatccagttaaagaatatggc
tgtgccccctggcccatggttgagaagttaattaaaaagtgtttgaaagaaaatcctcaa
gaaaggcctacttctgcccaggtctttgacattttgaattcagctgagttaatctgtctg
atgagacatatatcaatacctaaaaactttagtgttgaatgcatggtcgctacaaatcat
aacagcaagaatgcaagcatctggctgggctgtgggcacccgagcaaaggacagctctca
tttcttgacttaagtacagaaaagcacacttctgaggaagttactgatagtagaatactg
tgcctggctttggtgcatcttcctgttgaaaaggaaaattggattgtgtgtgggacacag
tctggcatgctcctggtcatcaatactgaagatggggcaaagagacatacccttgaaaag
atgactgattctgtgacttgcttgtattgcaatccctttcccaagcaaagcaagcaaaga
aattttcttctggtggggactgctgatggcaatttagcaatttttgaagataaaactgtt
aagtgtaaaggagccgctcctttgaagatactaaatataggaaatgtcagtactccactg
atgtgtttgagtgaatccatgaattcaactgaaaaaaacattatgtggggaggatgtggt
acgaaacttttctcattttctgatgatttcaccattcagaaactcattgagacaaagaca
aatcagctgttttcttatgcagcattcagtgattccaacatcatagcagtggtggtagac
acggctgtctacgtcgctaagaaaaatagcccatttgtggaagtacgggataagaaaact
gaaaaactctgtgaactaatagactgtgtgcactttttaaaggaggaaatggtaaaagta
aatgcagagtcaaaacacaagctctcttactctgggagagtgaaaaccctctgcctccag
aagaacactgctctctggataggaactggaggaggccatattttactccttgatctctcg
actcgtcgaattatacgtataattcacaatttttgtgattctgtcagagtcatgatgaca
gcacaattaggaagccttaaaaatgtcatgctggttttggggtatatccggaaaaatact
gaaggtacacaaccccaaaaagagatacaatcttgtttgtctgtttgggacatcaatctt
ccacatgaagtgcaaaatttagaaaaacatattgaagtgagaaaagaattagctgaaaaa
atgagaagaatatcggttgaataa
DBGET
integrated database retrieval system
