KEGG   Nyctereutes procyonoides (raccoon dog): 129508823
Entry
129508823         CDS       T09008                                 
Symbol
AKT3
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
npo  Nyctereutes procyonoides (raccoon dog)
Pathway
npo01521  EGFR tyrosine kinase inhibitor resistance
npo01522  Endocrine resistance
npo01524  Platinum drug resistance
npo04010  MAPK signaling pathway
npo04012  ErbB signaling pathway
npo04014  Ras signaling pathway
npo04015  Rap1 signaling pathway
npo04022  cGMP-PKG signaling pathway
npo04024  cAMP signaling pathway
npo04062  Chemokine signaling pathway
npo04066  HIF-1 signaling pathway
npo04068  FoxO signaling pathway
npo04071  Sphingolipid signaling pathway
npo04072  Phospholipase D signaling pathway
npo04140  Autophagy - animal
npo04150  mTOR signaling pathway
npo04151  PI3K-Akt signaling pathway
npo04152  AMPK signaling pathway
npo04210  Apoptosis
npo04211  Longevity regulating pathway
npo04213  Longevity regulating pathway - multiple species
npo04218  Cellular senescence
npo04261  Adrenergic signaling in cardiomyocytes
npo04370  VEGF signaling pathway
npo04371  Apelin signaling pathway
npo04380  Osteoclast differentiation
npo04510  Focal adhesion
npo04517  IgSF CAM signaling
npo04518  Integrin signaling
npo04550  Signaling pathways regulating pluripotency of stem cells
npo04611  Platelet activation
npo04613  Neutrophil extracellular trap formation
npo04620  Toll-like receptor signaling pathway
npo04625  C-type lectin receptor signaling pathway
npo04630  JAK-STAT signaling pathway
npo04660  T cell receptor signaling pathway
npo04662  B cell receptor signaling pathway
npo04664  Fc epsilon RI signaling pathway
npo04666  Fc gamma R-mediated phagocytosis
npo04668  TNF signaling pathway
npo04722  Neurotrophin signaling pathway
npo04725  Cholinergic synapse
npo04728  Dopaminergic synapse
npo04810  Regulation of actin cytoskeleton
npo04910  Insulin signaling pathway
npo04914  Progesterone-mediated oocyte maturation
npo04915  Estrogen signaling pathway
npo04917  Prolactin signaling pathway
npo04919  Thyroid hormone signaling pathway
npo04920  Adipocytokine signaling pathway
npo04922  Glucagon signaling pathway
npo04923  Regulation of lipolysis in adipocytes
npo04926  Relaxin signaling pathway
npo04929  GnRH secretion
npo04931  Insulin resistance
npo04932  Non-alcoholic fatty liver disease
npo04933  AGE-RAGE signaling pathway in diabetic complications
npo04935  Growth hormone synthesis, secretion and action
npo04936  Alcoholic liver disease
npo04973  Carbohydrate digestion and absorption
npo05010  Alzheimer disease
npo05017  Spinocerebellar ataxia
npo05132  Salmonella infection
npo05135  Yersinia infection
npo05142  Chagas disease
npo05145  Toxoplasmosis
npo05152  Tuberculosis
npo05160  Hepatitis C
npo05161  Hepatitis B
npo05162  Measles
npo05163  Human cytomegalovirus infection
npo05164  Influenza A
npo05165  Human papillomavirus infection
npo05166  Human T-cell leukemia virus 1 infection
npo05167  Kaposi sarcoma-associated herpesvirus infection
npo05168  Herpes simplex virus 1 infection
npo05169  Epstein-Barr virus infection
npo05170  Human immunodeficiency virus 1 infection
npo05200  Pathways in cancer
npo05205  Proteoglycans in cancer
npo05207  Chemical carcinogenesis - receptor activation
npo05208  Chemical carcinogenesis - reactive oxygen species
npo05210  Colorectal cancer
npo05211  Renal cell carcinoma
npo05212  Pancreatic cancer
npo05213  Endometrial cancer
npo05214  Glioma
npo05215  Prostate cancer
npo05218  Melanoma
npo05220  Chronic myeloid leukemia
npo05221  Acute myeloid leukemia
npo05222  Small cell lung cancer
npo05223  Non-small cell lung cancer
npo05224  Breast cancer
npo05225  Hepatocellular carcinoma
npo05226  Gastric cancer
npo05230  Central carbon metabolism in cancer
npo05231  Choline metabolism in cancer
npo05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
npo05415  Diabetic cardiomyopathy
npo05417  Lipid and atherosclerosis
npo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:npo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129508823 (AKT3)
   04012 ErbB signaling pathway
    129508823 (AKT3)
   04014 Ras signaling pathway
    129508823 (AKT3)
   04015 Rap1 signaling pathway
    129508823 (AKT3)
   04370 VEGF signaling pathway
    129508823 (AKT3)
   04371 Apelin signaling pathway
    129508823 (AKT3)
   04630 JAK-STAT signaling pathway
    129508823 (AKT3)
   04668 TNF signaling pathway
    129508823 (AKT3)
   04066 HIF-1 signaling pathway
    129508823 (AKT3)
   04068 FoxO signaling pathway
    129508823 (AKT3)
   04072 Phospholipase D signaling pathway
    129508823 (AKT3)
   04071 Sphingolipid signaling pathway
    129508823 (AKT3)
   04024 cAMP signaling pathway
    129508823 (AKT3)
   04022 cGMP-PKG signaling pathway
    129508823 (AKT3)
   04151 PI3K-Akt signaling pathway
    129508823 (AKT3)
   04152 AMPK signaling pathway
    129508823 (AKT3)
   04150 mTOR signaling pathway
    129508823 (AKT3)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    129508823 (AKT3)
   04518 Integrin signaling
    129508823 (AKT3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    129508823 (AKT3)
  09143 Cell growth and death
   04210 Apoptosis
    129508823 (AKT3)
   04218 Cellular senescence
    129508823 (AKT3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129508823 (AKT3)
   04550 Signaling pathways regulating pluripotency of stem cells
    129508823 (AKT3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    129508823 (AKT3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    129508823 (AKT3)
   04613 Neutrophil extracellular trap formation
    129508823 (AKT3)
   04620 Toll-like receptor signaling pathway
    129508823 (AKT3)
   04625 C-type lectin receptor signaling pathway
    129508823 (AKT3)
   04660 T cell receptor signaling pathway
    129508823 (AKT3)
   04662 B cell receptor signaling pathway
    129508823 (AKT3)
   04664 Fc epsilon RI signaling pathway
    129508823 (AKT3)
   04666 Fc gamma R-mediated phagocytosis
    129508823 (AKT3)
   04062 Chemokine signaling pathway
    129508823 (AKT3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    129508823 (AKT3)
   04922 Glucagon signaling pathway
    129508823 (AKT3)
   04923 Regulation of lipolysis in adipocytes
    129508823 (AKT3)
   04920 Adipocytokine signaling pathway
    129508823 (AKT3)
   04929 GnRH secretion
    129508823 (AKT3)
   04915 Estrogen signaling pathway
    129508823 (AKT3)
   04914 Progesterone-mediated oocyte maturation
    129508823 (AKT3)
   04917 Prolactin signaling pathway
    129508823 (AKT3)
   04926 Relaxin signaling pathway
    129508823 (AKT3)
   04935 Growth hormone synthesis, secretion and action
    129508823 (AKT3)
   04919 Thyroid hormone signaling pathway
    129508823 (AKT3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    129508823 (AKT3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    129508823 (AKT3)
  09156 Nervous system
   04725 Cholinergic synapse
    129508823 (AKT3)
   04728 Dopaminergic synapse
    129508823 (AKT3)
   04722 Neurotrophin signaling pathway
    129508823 (AKT3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    129508823 (AKT3)
  09149 Aging
   04211 Longevity regulating pathway
    129508823 (AKT3)
   04213 Longevity regulating pathway - multiple species
    129508823 (AKT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129508823 (AKT3)
   05205 Proteoglycans in cancer
    129508823 (AKT3)
   05207 Chemical carcinogenesis - receptor activation
    129508823 (AKT3)
   05208 Chemical carcinogenesis - reactive oxygen species
    129508823 (AKT3)
   05230 Central carbon metabolism in cancer
    129508823 (AKT3)
   05231 Choline metabolism in cancer
    129508823 (AKT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    129508823 (AKT3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    129508823 (AKT3)
   05212 Pancreatic cancer
    129508823 (AKT3)
   05225 Hepatocellular carcinoma
    129508823 (AKT3)
   05226 Gastric cancer
    129508823 (AKT3)
   05214 Glioma
    129508823 (AKT3)
   05221 Acute myeloid leukemia
    129508823 (AKT3)
   05220 Chronic myeloid leukemia
    129508823 (AKT3)
   05218 Melanoma
    129508823 (AKT3)
   05211 Renal cell carcinoma
    129508823 (AKT3)
   05215 Prostate cancer
    129508823 (AKT3)
   05213 Endometrial cancer
    129508823 (AKT3)
   05224 Breast cancer
    129508823 (AKT3)
   05222 Small cell lung cancer
    129508823 (AKT3)
   05223 Non-small cell lung cancer
    129508823 (AKT3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    129508823 (AKT3)
   05170 Human immunodeficiency virus 1 infection
    129508823 (AKT3)
   05161 Hepatitis B
    129508823 (AKT3)
   05160 Hepatitis C
    129508823 (AKT3)
   05164 Influenza A
    129508823 (AKT3)
   05162 Measles
    129508823 (AKT3)
   05168 Herpes simplex virus 1 infection
    129508823 (AKT3)
   05163 Human cytomegalovirus infection
    129508823 (AKT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    129508823 (AKT3)
   05169 Epstein-Barr virus infection
    129508823 (AKT3)
   05165 Human papillomavirus infection
    129508823 (AKT3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    129508823 (AKT3)
   05135 Yersinia infection
    129508823 (AKT3)
   05152 Tuberculosis
    129508823 (AKT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    129508823 (AKT3)
   05142 Chagas disease
    129508823 (AKT3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    129508823 (AKT3)
   05017 Spinocerebellar ataxia
    129508823 (AKT3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    129508823 (AKT3)
   05418 Fluid shear stress and atherosclerosis
    129508823 (AKT3)
   05415 Diabetic cardiomyopathy
    129508823 (AKT3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    129508823 (AKT3)
   04932 Non-alcoholic fatty liver disease
    129508823 (AKT3)
   04931 Insulin resistance
    129508823 (AKT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    129508823 (AKT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    129508823 (AKT3)
   01524 Platinum drug resistance
    129508823 (AKT3)
   01522 Endocrine resistance
    129508823 (AKT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:npo01001]
    129508823 (AKT3)
Enzymes [BR:npo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     129508823 (AKT3)
Protein kinases [BR:npo01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   129508823 (AKT3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 ABC1
Other DBs
NCBI-GeneID: 129508823
NCBI-ProteinID: XP_055179967
LinkDB
Position
Unknown
AA seq 479 aa
MSDVTVVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCVDNERRPHFPQFSYSASGRE
NT seq 1440 nt   +upstreamnt  +downstreamnt
atgagcgatgttaccgttgtgaaagaaggctgggttcagaagaggggagaatatataaaa
aactggaggccaagatatttccttttgaagacagatggctcattcataggatataaagag
aaacctcaagatgtggatttaccttatcccctcaacaacttttcagtggcaaaatgccag
ttaatgaaaacagaacgaccaaagccaaacacatttattatcagatgtctccagtggacc
actgttatagagagaacatttcatgtagatactccagaggaaagggaagagtggacagaa
gctattcaggcggtagcagacagacttcagagacaagaagaggagagaatgaattgtagt
ccaacttcacaaattgataatataggggaggaagagatggatgcttccacaacccatcat
aaaagaaagacaatgaatgattttgactatttgaaactactaggtaaaggcacttttggg
aaagttattttggttcgagagaaggcaagtgggaaatactatgctatgaagattctgaag
aaagaagtgattattgcaaaggatgaagtggcacatactctaacggaaagcagagtgtta
aagaacactcgacacccctttttaacatccttgaaatattccttccagacaaaagaccgt
ttgtgttttgtgatggaatatgttaatgggggagagctgtttttccatttgtcgagagag
cgggtgttctccgaggaccgcacacgtttctatggtgcagaaattgtctctgccttggac
tatctacattccggaaagattgtgtaccgtgatctcaagttggagaatttgatgctggat
aaagatggccacataaaaattacagattttggactttgcaaagaagggattacagatgca
gccaccatgaagacattctgtggcacaccagagtatctggcaccagaggtgttagaagac
aatgactatggccgagccgtggattggtggggactgggggtcgtcatgtatgaaatgatg
tgtgggaggttacctttctacaatcaggatcatgagaagctttttgaactaatactaatg
gaagacattaaattccctcgaacactctcttcagatgcaaaatcattgctttcggggctc
ttgataaaggatccaaataaacgccttggcgggggcccagatgatgcaaaagaaattatg
aggcacagtttcttctctggagtcaactggcaagatgtatacgataaaaagcttgtacct
ccttttaagcctcaagtaacatctgagacagataccagatatttcgatgaagaatttaca
gcgcagactattacaataacaccacctgaaaagtatgacgaggatggtatggactgcgtg
gacaacgagcggcggccgcacttccctcagttctcctactccgccagcggccgggagtaa

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