Nyctereutes procyonoides (raccoon dog): 129510932 Help Entry 129510932         CDS       T09008                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism npo  Nyctereutes procyonoides (raccoon dog) Pathway npo00230   Purine metabolism npo01100   Metabolic pathways npo01522   Endocrine resistance npo04015   Rap1 signaling pathway npo04020   Calcium signaling pathway npo04022   cGMP-PKG signaling pathway npo04024   cAMP signaling pathway npo04062   Chemokine signaling pathway npo04072   Phospholipase D signaling pathway npo04081   Hormone signaling npo04082   Neuroactive ligand signaling npo04114   Oocyte meiosis npo04211   Longevity regulating pathway npo04213   Longevity regulating pathway - multiple species npo04261   Adrenergic signaling in cardiomyocytes npo04270   Vascular smooth muscle contraction npo04371   Apelin signaling pathway npo04540   Gap junction npo04611   Platelet activation npo04713   Circadian entrainment npo04714   Thermogenesis npo04723   Retrograde endocannabinoid signaling npo04724   Glutamatergic synapse npo04725   Cholinergic synapse npo04727   GABAergic synapse npo04740   Olfactory transduction npo04750   Inflammatory mediator regulation of TRP channels npo04911   Insulin secretion npo04912   GnRH signaling pathway npo04913   Ovarian steroidogenesis npo04914   Progesterone-mediated oocyte maturation npo04915   Estrogen signaling pathway npo04916   Melanogenesis npo04918   Thyroid hormone synthesis npo04921   Oxytocin signaling pathway npo04923   Regulation of lipolysis in adipocytes npo04925   Aldosterone synthesis and secretion npo04926   Relaxin signaling pathway npo04927   Cortisol synthesis and secretion npo04928   Parathyroid hormone synthesis, secretion and action npo04934   Cushing syndrome npo04935   Growth hormone synthesis, secretion and action npo04962   Vasopressin-regulated water reabsorption npo04970   Salivary secretion npo04971   Gastric acid secretion npo04972   Pancreatic secretion npo04976   Bile secretion npo05032   Morphine addiction npo05163   Human cytomegalovirus infection npo05166   Human T-cell leukemia virus 1 infection npo05200   Pathways in cancer npo05207   Chemical carcinogenesis - receptor activation npo05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:npo00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     129510932 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     129510932 (ADCY3)    04371 Apelin signaling pathway     129510932 (ADCY3)    04020 Calcium signaling pathway     129510932 (ADCY3)    04072 Phospholipase D signaling pathway     129510932 (ADCY3)    04024 cAMP signaling pathway     129510932 (ADCY3)    04022 cGMP-PKG signaling pathway     129510932 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     129510932 (ADCY3)    04081 Hormone signaling     129510932 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     129510932 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     129510932 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     129510932 (ADCY3)    04062 Chemokine signaling pathway     129510932 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     129510932 (ADCY3)    04923 Regulation of lipolysis in adipocytes     129510932 (ADCY3)    04912 GnRH signaling pathway     129510932 (ADCY3)    04913 Ovarian steroidogenesis     129510932 (ADCY3)    04915 Estrogen signaling pathway     129510932 (ADCY3)    04914 Progesterone-mediated oocyte maturation     129510932 (ADCY3)    04921 Oxytocin signaling pathway     129510932 (ADCY3)    04926 Relaxin signaling pathway     129510932 (ADCY3)    04935 Growth hormone synthesis, secretion and action     129510932 (ADCY3)    04918 Thyroid hormone synthesis     129510932 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     129510932 (ADCY3)    04916 Melanogenesis     129510932 (ADCY3)    04925 Aldosterone synthesis and secretion     129510932 (ADCY3)    04927 Cortisol synthesis and secretion     129510932 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     129510932 (ADCY3)    04270 Vascular smooth muscle contraction     129510932 (ADCY3)   09154 Digestive system    04970 Salivary secretion     129510932 (ADCY3)    04971 Gastric acid secretion     129510932 (ADCY3)    04972 Pancreatic secretion     129510932 (ADCY3)    04976 Bile secretion     129510932 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     129510932 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     129510932 (ADCY3)    04727 GABAergic synapse     129510932 (ADCY3)    04725 Cholinergic synapse     129510932 (ADCY3)    04723 Retrograde endocannabinoid signaling     129510932 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     129510932 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     129510932 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     129510932 (ADCY3)    04213 Longevity regulating pathway - multiple species     129510932 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     129510932 (ADCY3)    04714 Thermogenesis     129510932 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     129510932 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     129510932 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     129510932 (ADCY3)    05163 Human cytomegalovirus infection     129510932 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     129510932 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     129510932 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     129510932 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     129510932 (ADCY3) Enzymes [BR:npo01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      129510932 (ADCY3) SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA YbyB Peptidase_S49_N Motif Other DBs NCBI-GeneID:  129510932 NCBI-ProteinID:  XP_055183260 LinkDB All DBs Position Unknown AA seq 1145 aa AA seqDB search MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRTSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVVAALFDCYVVLMCAVVFSSDKLAPLLVAAVGLLLDIL LFVLCKKGLLPDRVTRKVVPYLLWLLITAQIFSYLGLNFAGAHAASDTVGWQAFFVFSFF ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLQGMRLLREILANVFLYLCAIVVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCE YLDEKGIETYLIIASKPEVKKTAARRGPAGPPLLNGAPASSKPSSPALIETKEPNGSIHI SGSTSEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMTN YMTFVVGEVLLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYYTGPHNSTAGLEVDDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLVTGAVAVINIYAWRPIFDEYDRKRFQEHDFPMVALEKMQGLSTSGLNGTVRLPLVPSK YSMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFASSNKEEKSDKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEETQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPAAFPNGSSVTLPHQ VVDNS NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgccgaggaaccagggcttctccgagccggagtactcggccgagtactccgccgagtac tccgtgagcctgccctccgaccctgaccgcggggtgggccggacccacgaaatctcggtc cggacctccggctcctgcctctgcctgccgcggttcatgcggctgaccttcgtgcccgag tccttggagaacttgtaccagacctacttcaagcggcagcgccacgagaccctgctggtg ctggtggtggtcgcggccctcttcgactgctacgtggtgctcatgtgcgcggtggtcttc tccagcgacaagctggctccgctcctcgtggccgcggtgggcctgctgttggacatcctc ctcttcgtgctctgcaaaaaggggctgctccccgaccgggtcacccggaaagtggtgccc tacctgctgtggctgctgatcactgcccagattttctcctacctgggcctgaacttcgcc ggagcccatgcggccagcgacacggtgggctggcaggccttctttgtcttctccttcttc atcacgctgccgctcagcctcagccccatcgtcatcatctcggtggtctcctgtgtggtg cacacgctcgtcttgggggtcaccgtggcccagcagcagcaggacgggctgcagggcatg cgtttgctgagggagatcctggccaacgtcttcctctacctgtgcgccatcgtcgtgggc atcatgtcctactacatggccgaccgcaagcaccgaaaagccttcctggaggcccgccag tcactggaggtgaagatgaatctggaggagcagagccagcagcaggagaaccttatgctt tccatcctgcccaagcacgtggctgatgagatgctgaaggacatgaagaaggacgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccgccacgagaatgtcagcatc ctcttcgcggacatcgtgggcttcacccagctgtcttctgcctgcagtgcccaggagctc gtgaagctgctcaacgagctctttgcccgcttcgacaagctggcggccaaataccaccag ctgcggattaagatcctaggggactgttactactgcatctgcggcctgcccgactaccgg gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat gtgcgagagaagacgaagaccggagtggacatgcgcgtgggggtgcacacgggcaccgtg ctggggggcgtcctgggccagaagcgctggcagtacgacgtgtggtctaccgacgtcacc gtggccaacaagatggaggccggtggcatccccgggcgggtgcacatctcccagagtacc atggactgcctgaagggcgagttcgacgtggagccgggcgacgggggcagccgctgtgag tacctggacgagaagggcatcgagacctacctcatcatcgcgtccaagcccgaggtgaag aagaccgccgcccgccgcggccccgccggcccgcccctgctaaatggagcgccagcttct tccaagcccagctcccccgccctcattgagaccaaggagcccaacgggagcatccacatc agcggctccacatcggaggagcccgaggaacaggacgcccaggccgacaacccttcgttc cccaacccacgtcggaggctgcgcctgcaggacctggccgaccgggtggtggacgcctca gaggatgagcatgagctcaaccagctgctcaacgaggccctactggagcgcgagtctgcc caggtagtgaagaagagaaacaccttcctcctctccatgcggttcatggaccctgagatg gaaacccgctactcagtggagaaggaaaagcagagcggggctgccttcagctgctcctgc gttgtcctgctctgtacggccctggtcgagatactcatcgacccctggctaatgacaaac tacatgacctttgtggttggggaggttctacttctgatcctgacaatctgctcgctggct gccatctttccccgggcctttcctaagaagctcgtcgccttctcgacttggatcgaccgg acccgctgggccaggaacacatgggccatgttagccatcttcattctggttatggccaac gtcgtggacatgcttagctgtctccagtactacacaggaccacacaacagcactgcaggg ttggaggtggatgatggctgcgtagagaaccccaagtattacaactatgttgccgtgctg tccctcatcgctaccatcatgctggtgcaggtcagccacatggtgaaactcacgctcatg ctactcgtcacgggcgctgtggctgtcatcaacatctatgcctggcgccccatctttgac gaatacgaccgcaaacgtttccaggaacatgactttcccatggtcgccttagagaagatg cagggattgtccacctctgggctcaatggcactgtcaggctgcccctggtgccttccaag tactccatgacagtgatgatcttcgtcatgatgctgagcttttactacttctcacgccac gttgaaaaactggcaaggacactgtttttgtggaagattgaggtccatgaccagaaggaa cgtgtttacgagatgcggcgctggaatgaggccttggtcaccaacatgttgcctgagcac gtggcacgccacttcctggggtccaagaagagggatgaggagctgtatagccagtcttac gatgagattggagtcatgtttgcctctctacccaactttgccgacttctacacagaagag agcatcaataatggtggcattgagtgtctgcgcttcctcaatgagatcatctcagacttt gattctcttctggacaatcccaaattccgggtcatcaccaagatcaaaaccattggcagc acctatatggcagcttcaggagtcaccccagatgtcaacaccaacggctttgccagctcc aacaaggaggagaagtcagacaaagagcgctggcagcacctggctgatctggctgacttt gctctagccatgaaggatacactcacgaacatcaacaaccaatccttcaacaactttatg ctgcgcataggcatgaacaaaggaggggtactggctggggtcattggagcccggaaacca cactatgacatctggggcaatactgtcaatgtggccagcaggatggagtccacaggggtc atgggcaacattcaggtggtggaagaaacacaagccatccttcgagagtacggcttccgc tttgtgaggcgagggcccatctttgtgaaagggaagggggagctgctaacctttttcttg aaggggcgtgacaagccagctgccttccctaatggctcctccgtcaccctgccccaccag gtggtggacaactcctga

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