Nyctereutes procyonoides (raccoon dog): 129512445
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Entry
129512445 CDS
T09008
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
npo
Nyctereutes procyonoides (raccoon dog)
Pathway
npo00270
Cysteine and methionine metabolism
npo00480
Glutathione metabolism
npo01100
Metabolic pathways
npo01240
Biosynthesis of cofactors
npo04216
Ferroptosis
Module
npo_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
npo00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
129512445 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
129512445 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
129512445 (GCLC)
Enzymes [BR:
npo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
129512445 (GCLC)
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Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
129512445
NCBI-ProteinID:
XP_055185623
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All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVRLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDEEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARSLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
RGMFYFRKDICKGGNTVVDGYGKAQNSTEVAVEEYTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
LILKCNQIANELCECPELLGPAFRKVKYSGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccaaggctcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggagtacatgttggtgtcttttgatcat
gaaaataaaaaagtccggttggtcctgtccggagaggaagttcttgaaactctacaagaa
aagggggaaaggacaaacccaaaccatcctaccctgtggagaccagagtatggcagttac
atgattgaaggcacacctggacagccgtacggtggaaccatgtctgagttcaacacagtc
gaagacaacatgaggaaacgtcggaaggaagcaacttctctattaggagaaaatcaggct
ctctgtacaataacttcatttcccagattaggctgtcctgggttcacgctgccagaattc
aaacccaatccagttgaaggaggagcttccaagtccctcttctttcctgatgaagccata
aacaagcacccccgcttcagtaccctaacaagaaatatccgacataggagaggagaaaaa
gttgtcatcaatgtaccaatatttaaggacaagaatacaccatctccgtttatagaaacg
tttcctgaggatgaggaggcagccaaggcttctaagcctgatcatatttacatggatgcc
atgggatttgggatgggcaattgctgtcttcaggtaacgttccaagcttgcagcatatct
gaggccagatccctttatgatcagttggccactatctgtccaattgtcatggctttgagc
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagaacaat
aactataggatcagtaaatcccgctatgattcgatagacagttacttatctgagtgtggt
gagaaatacaatgacattgacttgacaatagataaagaaatctacgaacaactgctgcag
gaaggcattgatcatctcctggcccagcatgttgctcacctgttcattagagacccactg
actttgtttgaagagaaaatacacttggatgatgccaatgaatctgaccatttcgagaat
atccagtccacaaattggcagacgatgagatttaagccccctcctccaaactctgatatt
ggatggagagtagaattccgacccatggaggttcagttaacagactttgagaactctgca
tatgtggtgtttgtggtgctgcttaccagagtgatcctttcatacaaactggattttctc
attccactatcaaaggttgatgaaaatatgaaagttgcacagaaacgagatgctgtcttg
cggggaatgttttatttcaggaaagatatttgcaaaggtggcaacactgtagtagatggc
tacggcaaggcccagaacagcacagaagtggctgtagaggagtataccctgatgagcata
gacaccatcatcaacgggaaggaaggtgtgtttcctgggctgatcccaattctgaactct
taccttgaaaacatggaagtggatgtggacaccagatgtagtattctgaactacctaaag
ctaattaagaagagagcatctggtgaactaatgacagttgccaggtggatgagagagttt
attgcaaaccatcctgactacaagcaagacagtgtgataactgatgaaatgaactacagc
cttattttaaagtgtaaccaaattgcaaatgaattatgtgaatgtccagagttacttgga
ccagcatttaggaaagtaaaatatagtggaagtaaaactgactcttccaactag
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