Nyctereutes procyonoides (raccoon dog): 129515953
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Entry
129515953 CDS
T09008
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
npo
Nyctereutes procyonoides (raccoon dog)
Pathway
npo00220
Arginine biosynthesis
npo00330
Arginine and proline metabolism
npo01100
Metabolic pathways
npo04020
Calcium signaling pathway
npo04022
cGMP-PKG signaling pathway
npo04066
HIF-1 signaling pathway
npo04071
Sphingolipid signaling pathway
npo04151
PI3K-Akt signaling pathway
npo04370
VEGF signaling pathway
npo04371
Apelin signaling pathway
npo04611
Platelet activation
npo04915
Estrogen signaling pathway
npo04921
Oxytocin signaling pathway
npo04926
Relaxin signaling pathway
npo04931
Insulin resistance
npo04933
AGE-RAGE signaling pathway in diabetic complications
npo05415
Diabetic cardiomyopathy
npo05417
Lipid and atherosclerosis
npo05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
npo00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
129515953 (NOS3)
00330 Arginine and proline metabolism
129515953 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
129515953 (NOS3)
04371 Apelin signaling pathway
129515953 (NOS3)
04066 HIF-1 signaling pathway
129515953 (NOS3)
04020 Calcium signaling pathway
129515953 (NOS3)
04071 Sphingolipid signaling pathway
129515953 (NOS3)
04022 cGMP-PKG signaling pathway
129515953 (NOS3)
04151 PI3K-Akt signaling pathway
129515953 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
129515953 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
129515953 (NOS3)
04921 Oxytocin signaling pathway
129515953 (NOS3)
04926 Relaxin signaling pathway
129515953 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
129515953 (NOS3)
05418 Fluid shear stress and atherosclerosis
129515953 (NOS3)
05415 Diabetic cardiomyopathy
129515953 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
129515953 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
129515953 (NOS3)
Enzymes [BR:
npo01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
129515953 (NOS3)
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GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
DUF8466
Motif
Other DBs
NCBI-GeneID:
129515953
NCBI-ProteinID:
XP_055191184
LinkDB
All DBs
Position
Unknown
AA seq
1213 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPTSEPSRAPVLAPPPSPPPAPDHSSPP
LTRPPDGPKFPRVKNWEVGSITYDTLSAQSQQDGPCTPRRCLGSLVFPRKLQSRPSQDPA
PPEQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAW
RNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRASGR
GDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDE
PPELFALPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYM
STEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIV
DHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFRYQTD
PWKGSASKGAGVTRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQL
GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYN
SSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYP
HFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKA
AARDIFSPKRTWKRQRYRLSTQAEGLQLLPGLIHVHRRKMVQATVLAVENLQSSKSTRAT
ILVRLDTGSQEALQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPGEPVAVEQLEKGSPD
LPCTPSPGSPPPSWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEESSEQQEL
ESLSQDPRRYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHP
GEIHLTVAVLAYRTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPSLPCI
LVGPGTGIAPFRGFWQERLHDIDSKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVF
GRVLTAFSREPDRPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRI
LATEGDMELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVP
WAFDPPGPDTAGP
NT seq
3642 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccaggagcccgggcccccttgtggcctggggctgggc
ctgggcctggggctatgtggcaagcagggccctgcctccccgacctcagagcccagccgg
gcaccggtcctggcgcccccaccctcgcccccaccagcaccagaccacagcagccccccg
ctcacccggcctccagatgggcccaagttccctcgtgtgaagaactgggaggtggggagc
atcacctatgacaccttgagtgcccagtcacagcaggatgggccctgcaccccgagacgc
tgtctgggctctctggtatttccacggaaactgcagagccggccctcccaggaccctgca
ccccctgagcagctgctgagccaggccagggacttcatcaaccagtactacagctccatc
aagaggagtggctcccaggcccatgagcagaggcttcaagaggtggaagccgaggtagca
gccacaggcacctatcagcttcgggaaagcgagctggtgttcggggccaagcaggcctgg
cgaaacgctccccgctgcgtgggccggatccagtgggggaagctgcaggtgtttgatgcc
cgggattgcagctctgcccaagagatgttcacctacatctgcaaccacatcaagtatgcc
accaaccggggcaacctccgctcggccatcacagtgttcccccagcgtgcctcaggccgc
ggagacttccgaatttggaacagccagctggtgcgctatgcgggctacaggcagcaggat
ggctctgtgcggggggacccagccaacgtggagatcactgagctctgcatccagcatggc
tggactccaggaaacggccgctttgatgtgctgcccctactgctccaggccccagatgag
cccccagaactctttgctctaccccccgaactggttctcgaggtgcccctggagcacccc
acgctggagtggtttgcagccctgggcctgcgctggtatgccctcccagcggtgagcaac
atgctgctggaaattggggggctggagttccctgcggcccccttcagcggctggtacatg
agcactgagattggcacgcggaacctgtgtgaccctcatcgatacaacatcctggaggat
gtggctgtctgcatggacttggataccaggaccacctcatccctgtggaaagacaaggca
gcagtggaaatcaacttggctgtgctgcacagttaccagctggccaaagtgaccatcgtg
gaccaccatgctgccacagcctccttcatgaagcacctggagaacgagcagaaggccagg
gggggttgccctgctgactgggcctggatcgtgccccccatctctggcagcctcacccct
gttttccatcaggagatggtcaactacgtcctgtccccggccttccgctatcagacagac
ccgtggaaggggagtgcatccaagggtgccggcgtcaccaggaagaaaacctttaaggaa
gtggccaatgcggtgaagatctctgcctcactcatgggcactgtgatggcaaagcgagtg
aaggcaacaatcctctatggctccgagactggccgggcccagagctatgcacagcagctg
gggagactcttccggaaggctttcgacccccgggtcctgtgcatggatgagtatgacgtg
gtgtcccttgagcatgagacgctggtgttggtggtgaccagcacatttgggaatggtgat
cccccggagaatggagagagttttgcggcggccctgatggagatgtcgggtccctacaac
agctcccctcggccagaacagcacaagagttacaaaatccgcttcaacagtgtctcctgc
tcagacccactggtgtcctcctggaggcggaagagaaaggagtccagtaacacagacagt
gctggggcactgggtaccctcaggttctgtgtgttcgggctgggctcccgggcatacccc
cacttttgtgcctttgctcgtgcggtggacacacggctggaagagctgggtggggagcgg
ctgctgcagctgggccaaggagatgagctgtgtggccaggaggaggccttccgaggctgg
gcccaggccgccttccaggcctcctgtgagaccttctgcgtgggagaggatgccaaggct
gccgcccgggacatattcagccccaaacggacctggaagcgccagaggtaccggctgagc
acccaggctgagggcctccagctgctgccaggactgatccatgtgcataggaggaagatg
gtccaggctactgtcctcgcggtggaaaacctgcaaagcagcaagtccacccgggccacg
atcctggtgcgcctggacactggaagccaggaggcgctgcagtaccagccaggggaccac
attggcatctgcccgcccaaccggcctggccttgtggaggcgctgctgagccgggtggag
gatccaccgccaccaggagagccagtggcagtggagcagctggagaagggcagccctgat
ctcccctgtacaccatcaccaggtagcccaccccccagctgggttcgggaccctcgcctg
cccccatgcacactgcgccaggctctcaccttcttcctggacatcacttccccgcccagc
cctcaactccttcgactgctcagcaccctggctgaagagtccagtgaacagcaggagctt
gagagcctcagccaggacccccggcgctatgaggaatggaagtggttccgctgccccaca
ctgctggaggtactggaacagttcccatcggtggcactgcccgcccccctgctcctcacc
cagctgcccctgctccagccccggtactactcggtcagctcagcacccagtgcccaccca
ggagagatccacctcacagtagctgtgctggcatacaggacacaggatggactgggcccc
cttcattatggagtctgctccacatggctaagccaacttaaggccggagatcctgtaccc
tgcttcatcaggggggctccctccttccggctgccacctgatcccagtctgccttgcatc
ctagtgggtcctggtacgggtattgccccctttcggggtttctggcaggagcggctgcac
gacattgacagcaaagggctgcagcccgcccccatgactctggtgttcggctgccgatgc
tcccagctcgaccacctttaccgcgacgaggtgcaggatgcccagcagcgcggagttttt
gggcgcgtcctcaccgccttctcccgggagcccgaccgccctaagacgtacgtgcaggac
atcctgcggacggagctggctgctgaggtgcaccgcgtgctgtgcctcgagcggggccac
atgtttgtgtgcggcgacgtcaccatggcaaccagcgtcctgcagacggtgcagcgaatc
ctggcgacggagggcgacatggagctggacgaggccggcgacgtcatcggcgtgctgcgg
gatcagcaacgctatcacgaggacattttcgggctcacactgcgcacgcaggaggtgaca
agccgcatccgcacccagagcttctccttgcaggagcggcatctgcggggcgcggtgccc
tgggcgttcgacccgcccggcccagacaccgccggcccctga
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