Nyctereutes procyonoides (raccoon dog): 129521545
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Entry
129521545 CDS
T09008
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
npo
Nyctereutes procyonoides (raccoon dog)
Pathway
npo00310
Lysine degradation
npo01100
Metabolic pathways
npo05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
npo00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
129521545 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
129521545 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
npo03036
]
129521545 (DOT1L)
Enzymes [BR:
npo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
129521545 (DOT1L)
Chromosome and associated proteins [BR:
npo03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
129521545 (DOT1L)
HMT complexes
Dot1-containing complex
129521545 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
129521545
NCBI-ProteinID:
XP_055199093
LinkDB
All DBs
Position
Unknown
AA seq
1710 aa
AA seq
DB search
MPWAGAVRWPCRVPGPCTTGGCKPCPFVFQDKHHDAAHEIIETIRWVCEEIPDLKLAMEN
YVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNH
SVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAAT
NCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSV
IFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELS
PLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPT
KVPENKAAVPADTPMDSGAEEEKAGATTIKKPSPSKARKKKLNKKGRKMAGRKRGRPKKM
STANPERKPKKSQTALDLLHAQAASQTAAPSPQDAYKSPHSPFYQLPPSVQRHPPDQLLL
APTPPALQKLLESFKIQYLQFLAYTKTAQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQ
AQKEEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLQKDNRELRSQSL
QLLKARCEELKLDWSTLSLENLLKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELL
QLKSCVPPDEALSAHLRGKSALGRELEADPSRLHLDLDCSKFSLPHFSSASPELSMNGHA
ANYELCSALSRPSSKQNTPQYLASPLDQEVVPCTPSHSSRSRLEKMSGLALPDYTRLSPA
KLVLRRHLSQDHATSGKPAASELHPRAEHTKENGLPYQSPGITNGIKLSPQDPRPSSPVA
LQMTGERGSEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKV
RSTPSPVPQTRESSSTLEKQMGTNTHSAGSKSLASTPAGFYTGSVAVSGALAGSPAPLAP
GAEPSAFDEVSGSGSLFASMGSCSSTPQHPPLLPQSRGSGGASPAHPLCASPRLSSVAQG
PLPDANKGDLPSEAGFSDPEGEAKRRIVFTISAGGSSAKQSPPSKPSPLPTGARGDSSQG
HGSDSRKRGRRKRASAGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPL
EITAISSPESLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPGSAR
IERKIATISLESKSPPKTLESGGGLAGRKPTPASEPTNSSKWKSTFSPISDLGLAKCADS
PLQAGSSLSQNSLFTFRPPLDDPGSADTKLAAHPRKSFPGALSGAGGLSPSSNPPNGFAF
GGGLAADLSLHSFSDGASLSHKVPEAASLGAPLSFPAPRGKEGGATEPGAFVNKRQLDGL
GGPKGREAGELGLPVCGPPDKASLTHSKPTKGRDREPDLKNGHNLFISAATVPPAGLLSG
PGLATVASSAVSAAPSAQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFSSVPAAA
GLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGVFNHAVPSASAHPFGASFGSGAACRSAT
LSLTPLQAVASAPASSFQAPPPPPPGQPALPAPPPPNAALPPAPALLPANSEPVLLQNLA
SLPANQAFLPASSAASLQPANASLSIKLASLPHKAPRPSFTVHHQPLPGLALAQAAPVIP
QASSTGPSAVWVSLGMPPPYAARLAGVKPR
NT seq
5133 nt
NT seq
+upstream
nt +downstream
nt
atgccctgggccggggctgtccgttggccttgccgggtccccggaccctgcaccactgga
gggtgtaaaccctgtccctttgtctttcaggacaaacaccacgatgctgctcatgaaatc
atcgagaccatccgatgggtctgtgaagagatcccagacctcaagcttgctatggagaat
tacgttttaatcgactacgacaccaaaagcttcgaaagcatgcagaggctctgtgacaaa
tacaaccgtgccatcgacagcatccaccagctgtggaaggggaccactcagcccatgaaa
ctgaacactcggccgtccaacgggctcctgaggcatatcctgcagcaggtgtacaaccac
tcggtgacggaccccgagaagctcaacaactatgagcccttctccccggaggtgtacggg
gagacctcctttgacttggttgcacagatgatcgacgagatcaagatgaccgaggatgac
ctgtttgtggacctgggcagtggagtgggccaggttgtgctgcaggtcgccgcggccacc
aactgcaaacatcactatggcgtggagaaagctgacatcccagccaagtacgcggagacc
atggaccgagagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacaca
ctggaaagaggcgacttcctctcagaagagtggagagagcggattgccaacacaagtgtt
atatttgtgaataattttgcctttggtcctgaggtggatcaccagctgaaggagcggttt
gcgaacatgaaggaaggcggcagaattgtgtcctcgaagcccttcgcacctctcaacttc
cggataaacagcagaaacttgagcgacatcggcaccatcatgcgcgttgtggagctctcg
cccctgaaaggctcggtgtcctggacggggaagccggtctcctactacctgcacactatc
gaccgcaccatacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggaa
caagaggcagctcggcgccggcagcagcgagaaaacaagagcaacacgaccactcccacc
aaggtgcccgagaacaaggctgctgtgcctgccgacacccctatggattctggtgccgag
gaagaaaaggctggggcaaccaccatcaaaaagccgtctccctccaaagcccggaagaag
aagctgaacaagaaggggcggaagatggccggccggaagcgtgggcgtcccaagaagatg
agcactgcgaaccccgagcgtaagcccaagaagagccaaactgcactggacctcctgcat
gcccaggccgcgtctcagacggcagcgccctcgccgcaggatgcgtacaagtcacctcat
agcccgttttatcagctacctcccagtgtgcagcggcacccccctgaccagctgctgctg
gcacccaccccacccgcactgcagaagctgctagaatccttcaagattcagtacttgcag
ttcttggcgtacaccaagaccgcccagtacaaggccagcctgcagcagctgctggaccag
gagaaggagaagaacgcccggttgctaggtgctgcgcagcagctgtttggccactgccag
gcccagaaagaggagatcaagaggctcttccagcagaaactggatgagctgggagtgaag
gcgctgacctacaacgacctgattcaggcacagaaggagatctcggctcataatcagcag
ctgagggaacagacggagcagctgcagaaggacaacagggagctgaggagccagagccta
cagctgctcaaggctcggtgtgaggagctaaagctggactggtccacgctgtccctggag
aacctgctgaaggagaagcaggccctgagaagccagatctccgagaagcagaggcactgc
ctggagctgcagatcagcatcgtggagctggagaagagccagcggcagcaggagctcctg
cagctcaagtcctgtgtgcctccagacgaggccctgtcagcgcacctgcgtgggaagagt
gccctgggccgggagctggaggctgaccccagccgactgcacctcgacctggactgctcc
aagttctctctgccccacttcagcagcgcaagcccagagctctccatgaacggccacgca
gccaactacgagctctgcagcgcgctgagccggccctcatccaagcagaacacgcctcag
tacctggcctccccgctggaccaggaagtcgtaccctgcacccccagccacagcagccgg
tcgaggctcgagaagatgtctggcctggccttgcccgactacacccggctttccccggcc
aagctggtgctgcggcgtcacctgagccaggaccacgcgaccagcggcaagccagccgcc
agtgagctgcatccacgagccgagcataccaaggagaacggccttccataccagagccct
ggcatcacaaatggcatcaagctgagccctcaggaccctcgaccctcgtcccccgtggcc
ttacagatgacaggggagaggggcagcgagaagggcttgaaggagcgtgcctatgccagc
agcggagaggccatcaccagcctgcccgttagcatcccgctcagcaccgtgcagcccagt
aagctgcccgtcagcatccctctggccagtgtggtgctgcccagccgcgccgagaaagtg
agaagcacccccagccctgtgccgcagacccgagagtcctcgtccacacttgaaaagcag
atgggcacaaacacccacagcgctggaagcaaaagccttgcctcaactcccgcaggcttc
tacacgggctcggtggccgtcagtggggccctggcaggcagcccagcgcccctggctcct
ggagcagagcccagcgccttcgacgaggtctctggctcaggaagcctgttcgccagcatg
gggtcctgcagctccaccccgcagcacccgcccctgctgccacagtcccgtggctccggc
ggagcctcacccgcccatccgctctgtgccagtccgcggctcagcagtgtcgcccagggc
ccgctccccgatgccaacaaaggggaccttccgtccgaggcgggcttctcagaccctgag
ggcgaagccaagaggaggattgtctttaccatctcagctggtggcagcagtgccaaacag
tcgcctcccagcaaacccagccctctgcccacgggtgcccgcggggacagcagccagggc
catgggtcggacagccgcaagcggggcaggagaaagcgggcctcggcggggaccccgagc
ctgagctcaggcgtatcgcctaagcgtcgggccttgccatctgttgccggcctcttcacg
cagtcttcagggtccccgctgaacctcaactctatggtcagcaacattaaccagcctttg
gaaatcacggccatctcgtcccccgagagcctgaagagctcccctgtcccttaccaggac
aacgaccagccgcccgttctcaagaaggagaagcccctgagccagaccaatggggcccac
tactccccactgacctcagatgaggagcagggctctgaggacgagccaggcagtgccaga
atcgagagaaaaattgcaacaatttccttagaaagcaaatcccctccaaaaaccttggaa
agcggtggtggcctggccgggaggaagccgacccctgccagcgagcccaccaacagcagc
aagtggaagtccaccttctcacccatctccgacctcggcctggccaagtgcgccgacagc
ccgctgcaggccggctcctccctgagccagaactccctgttcactttccggcctcccctc
gatgatcccggctcggccgacaccaagctggctgcccaccccaggaaaagctttcccggc
gctctgtcgggggccggtgggctgagcccaagcagcaaccctcccaacggcttcgccttc
ggtgggggcctggccgccgacctcagtttacacagcttcagcgatggtgcttctctctcc
cacaaggtccccgaggcggccagcctgggcgcacccctgagctttcctgccccgcggggc
aaggagggcggtgccacagagcccggcgcctttgtgaacaagaggcagctggacggactg
ggcggcccgaagggcagggaggcgggcgagctgggcctgccagtgtgcgggcccccggac
aaggcctcgctgacgcacagcaagcccaccaagggccgggaccgcgagcccgacctgaag
aatggccacaacctcttcatttctgctgccaccgtgcctcccgcgggcctcctcagcggc
cccggcctcgccacggtggcatcctcggcagtcagcgcggccccgtctgcccagactcac
cgccccttcctgggcacctttgcccccgggccgcagttcgccctgggtcccatgtccctg
caggccaacctgggctcgtctgtgctgcagtccttgttcagctccgtgccggctgctgct
ggcctggtgcacgtctcgtccgctgcaaccagactgaccaactcgcacgccatgggcagc
ttttcctcgggggtggcaggcggcgcagttggaggtgtctttaaccacgcggtgccttcc
gcctccgctcatccgtttggagccagtttcggcagcggggctgcgtgtcgcagcgccacg
ctgagcttaaccccgctgcaggcggtggccagcgcccctgcgtcttcctttcaggcccca
cccccgccccctccggggcagcccgccctccccgcaccccctccccctaacgccgccttg
cctcctgcccccgcgctgctcccggctaactctgagcccgtgcttctgcagaaccttgcg
tccctcccagctaaccaggctttcttacccgcctcctctgccgcctctctgcagcctgct
aacgcctctctgtccatcaagctcgcctccctcccgcacaaggccccccgcccctccttc
acggtgcaccaccagcccctgcccgggctggccctggcccaggccgcgcccgtgatcccg
caggccagctccacggggccgtctgccgtgtgggtttcccttggcatgccgcctccgtat
gccgcgcgccttgcgggggttaagccgagataa
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integrated database retrieval system
