KEGG   Nyctereutes procyonoides (raccoon dog): 129522825
Entry
129522825         CDS       T09008                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
npo  Nyctereutes procyonoides (raccoon dog)
Pathway
npo01522  Endocrine resistance
npo04010  MAPK signaling pathway
npo04012  ErbB signaling pathway
npo04014  Ras signaling pathway
npo04024  cAMP signaling pathway
npo04068  FoxO signaling pathway
npo04071  Sphingolipid signaling pathway
npo04137  Mitophagy - animal
npo04140  Autophagy - animal
npo04141  Protein processing in endoplasmic reticulum
npo04210  Apoptosis
npo04215  Apoptosis - multiple species
npo04217  Necroptosis
npo04310  Wnt signaling pathway
npo04380  Osteoclast differentiation
npo04510  Focal adhesion
npo04517  IgSF CAM signaling
npo04519  Cadherin signaling
npo04530  Tight junction
npo04620  Toll-like receptor signaling pathway
npo04621  NOD-like receptor signaling pathway
npo04622  RIG-I-like receptor signaling pathway
npo04625  C-type lectin receptor signaling pathway
npo04657  IL-17 signaling pathway
npo04658  Th1 and Th2 cell differentiation
npo04659  Th17 cell differentiation
npo04660  T cell receptor signaling pathway
npo04664  Fc epsilon RI signaling pathway
npo04668  TNF signaling pathway
npo04722  Neurotrophin signaling pathway
npo04723  Retrograde endocannabinoid signaling
npo04728  Dopaminergic synapse
npo04750  Inflammatory mediator regulation of TRP channels
npo04910  Insulin signaling pathway
npo04912  GnRH signaling pathway
npo04914  Progesterone-mediated oocyte maturation
npo04917  Prolactin signaling pathway
npo04920  Adipocytokine signaling pathway
npo04926  Relaxin signaling pathway
npo04930  Type II diabetes mellitus
npo04931  Insulin resistance
npo04932  Non-alcoholic fatty liver disease
npo04933  AGE-RAGE signaling pathway in diabetic complications
npo04935  Growth hormone synthesis, secretion and action
npo04936  Alcoholic liver disease
npo05010  Alzheimer disease
npo05012  Parkinson disease
npo05016  Huntington disease
npo05017  Spinocerebellar ataxia
npo05020  Prion disease
npo05022  Pathways of neurodegeneration - multiple diseases
npo05132  Salmonella infection
npo05133  Pertussis
npo05135  Yersinia infection
npo05142  Chagas disease
npo05145  Toxoplasmosis
npo05152  Tuberculosis
npo05161  Hepatitis B
npo05162  Measles
npo05166  Human T-cell leukemia virus 1 infection
npo05167  Kaposi sarcoma-associated herpesvirus infection
npo05169  Epstein-Barr virus infection
npo05170  Human immunodeficiency virus 1 infection
npo05171  Coronavirus disease - COVID-19
npo05200  Pathways in cancer
npo05208  Chemical carcinogenesis - reactive oxygen species
npo05210  Colorectal cancer
npo05212  Pancreatic cancer
npo05231  Choline metabolism in cancer
npo05415  Diabetic cardiomyopathy
npo05417  Lipid and atherosclerosis
npo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:npo00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    129522825 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129522825 (MAPK8)
   04012 ErbB signaling pathway
    129522825 (MAPK8)
   04014 Ras signaling pathway
    129522825 (MAPK8)
   04310 Wnt signaling pathway
    129522825 (MAPK8)
   04668 TNF signaling pathway
    129522825 (MAPK8)
   04068 FoxO signaling pathway
    129522825 (MAPK8)
   04071 Sphingolipid signaling pathway
    129522825 (MAPK8)
   04024 cAMP signaling pathway
    129522825 (MAPK8)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    129522825 (MAPK8)
   04519 Cadherin signaling
    129522825 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    129522825 (MAPK8)
   04137 Mitophagy - animal
    129522825 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    129522825 (MAPK8)
   04215 Apoptosis - multiple species
    129522825 (MAPK8)
   04217 Necroptosis
    129522825 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129522825 (MAPK8)
   04530 Tight junction
    129522825 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    129522825 (MAPK8)
   04621 NOD-like receptor signaling pathway
    129522825 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    129522825 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    129522825 (MAPK8)
   04660 T cell receptor signaling pathway
    129522825 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    129522825 (MAPK8)
   04659 Th17 cell differentiation
    129522825 (MAPK8)
   04657 IL-17 signaling pathway
    129522825 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    129522825 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    129522825 (MAPK8)
   04920 Adipocytokine signaling pathway
    129522825 (MAPK8)
   04912 GnRH signaling pathway
    129522825 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    129522825 (MAPK8)
   04917 Prolactin signaling pathway
    129522825 (MAPK8)
   04926 Relaxin signaling pathway
    129522825 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    129522825 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    129522825 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    129522825 (MAPK8)
   04722 Neurotrophin signaling pathway
    129522825 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    129522825 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    129522825 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129522825 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    129522825 (MAPK8)
   05231 Choline metabolism in cancer
    129522825 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    129522825 (MAPK8)
   05212 Pancreatic cancer
    129522825 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    129522825 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    129522825 (MAPK8)
   05161 Hepatitis B
    129522825 (MAPK8)
   05171 Coronavirus disease - COVID-19
    129522825 (MAPK8)
   05162 Measles
    129522825 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    129522825 (MAPK8)
   05169 Epstein-Barr virus infection
    129522825 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    129522825 (MAPK8)
   05135 Yersinia infection
    129522825 (MAPK8)
   05133 Pertussis
    129522825 (MAPK8)
   05152 Tuberculosis
    129522825 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    129522825 (MAPK8)
   05142 Chagas disease
    129522825 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    129522825 (MAPK8)
   05012 Parkinson disease
    129522825 (MAPK8)
   05016 Huntington disease
    129522825 (MAPK8)
   05017 Spinocerebellar ataxia
    129522825 (MAPK8)
   05020 Prion disease
    129522825 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    129522825 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    129522825 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    129522825 (MAPK8)
   05415 Diabetic cardiomyopathy
    129522825 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    129522825 (MAPK8)
   04936 Alcoholic liver disease
    129522825 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    129522825 (MAPK8)
   04931 Insulin resistance
    129522825 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    129522825 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    129522825 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:npo01001]
    129522825 (MAPK8)
Enzymes [BR:npo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     129522825 (MAPK8)
Protein kinases [BR:npo01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   129522825 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH
Other DBs
NCBI-GeneID: 129522825
NCBI-ProteinID: XP_055201250
LinkDB
Position
Unknown
AA seq 427 aa
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacagcaatttttatagtgtagagattggagattccacattt
acagtcttgaaacgatatcagaatttaaaacctataggctcaggagctcaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccggcca
tttcaaaatcagactcatgctaaacgggcttacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggacgcaaatctttgccaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatagtggtaaaa
tcagactgcactttgaagattcttgactttggactggccaggactgcaggaactagtttt
atgatgacaccttatgtagtgactcgctactacagagcacctgaggtcatcctagggatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgccctgaattcatgaagaaactacagccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccccgatgtacttttc
ccagctgactcagaacacaacaaacttaaagccagtcaggcaagggatttgttatccaaa
atgctggtaattgatgcatctaaaaggatctctgtagatgaagctctccagcacccatat
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatacctgacaag
cagttagatgaaagggaacatacaatagaagagtggaaagagttaatatacaaagaagtt
atggacttggaggagagaaccaagaatggagttatacggggacagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcgtcatcatctgtcaatgatgtgtct
tcaatgtcaacagatccaactttggcctcagatacagacagcagtttagaagcatcagct
ggacctctgggctgctgtagatga

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