Nanorana parkeri (Xizang Plateau frog): 108788961
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Entry
108788961 CDS
T04897
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
npr
Nanorana parkeri (Xizang Plateau frog)
Pathway
npr00270
Cysteine and methionine metabolism
npr00480
Glutathione metabolism
npr01100
Metabolic pathways
npr01240
Biosynthesis of cofactors
npr04216
Ferroptosis
Module
npr_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
npr00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
108788961 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
108788961 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
108788961 (GCLC)
Enzymes [BR:
npr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
108788961 (GCLC)
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GFIT
Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
108788961
NCBI-ProteinID:
XP_018414370
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All DBs
Position
Unknown
AA seq
636 aa
AA seq
DB search
MGLLSAGSPLSWEETKKYADHVRQHGIIQFLNIYHKVKERQKDVLKWGDEVEYMLVAFDH
ENQKARLVLKGGDMLETLQDRGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGVMAEFNTV
EDNMLKRRQEASLLLPDNQSICTITSFPRLGSPGFTLPEFPPTPVEKGASKSLFFPDEAI
NMHPRFSTLTRNIRHRRGEKVAINVPIFKDLNTPSPFIEKFPNATGDDAKAAMPDHIYMD
AMGFGMGNCCLQVTFQACSIAEARCLYDQLATICPIAMALSAAAPFYRGYVSDIDCRWGV
ISASVDDRTKEERGLEPLKNNKYRISKSRYDSIDSYLSTCGEKYNDIDLTIDKEIYSQLT
REGIDPLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKMAQKRDAV
RQGMFYFKKDICKVGIAAVDGCYATLNGTEAETEEYTLMSIDTIINGKEGVFPGLLPILN
SYLENMEVDVDTRCTILNYLKLIKKRASGELMTAARWMREFVSNHPDYKQDSVITDKINY
DLMVKCNQIANGQTGCPGLVGFTTSKTNPSGSKTTV
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atgggtctgctatctgccggctctccgcttagctgggaagagaccaagaagtacgcggat
cacgtccggcaacacggcatcatccagttcctgaacatctaccataaggtgaaggaacgc
cagaaggacgtgctgaaatggggcgatgaggtggagtacatgttagttgccttcgatcat
gaaaatcaaaaggctcgtttagtactcaaaggaggagacatgcttgaaaccctacaagac
cgaggtgaaaaaataaacccaaatcacccaaccctctggagaccagagtatggcagctac
atgattgaggggacaccaggacagccctatggaggtgtgatggcagagtttaacaccgtg
gaagacaatatgctgaaacgtcggcaggaggcctccttgcttctaccagacaaccagtcc
atatgcactatcacctcttttccaagattgggatctcctggatttacattgccagaattt
ccacctaccccagtggagaagggagcatccaagtcacttttctttccagatgaagctatc
aacatgcatccacgatttagtacattgaccaggaatattcggcaccggcgtggagaaaaa
gtggctattaatgttccaatttttaaagacctgaacactccttctccttttattgagaaa
tttccaaatgctactggtgatgatgcaaaagccgcaatgcctgatcatatttacatggat
gctatgggttttgggatgggcaactgttgccttcaggtcacttttcaagcttgcagcatt
gcagaagcaagatgcctgtatgaccagctggctactatatgtccaattgcgatggccctg
agtgctgctgctcctttctacagaggatatgtgtcagacattgactgtcgatggggagtt
atttctgcctccgtagatgatcgaacgaaagaggaaagaggcctagagcctctgaagaat
aacaagtacagaatcagtaaatctcgatacgattctatagacagttatctgtctacctgt
ggtgaaaagtacaacgacattgatttgactattgataaagaaatctatagccaactaaca
agagagggtattgaccccctcttggcccaacacattgcacatctcttcatcagagatcct
ctgacattgtttgaagagaagatacatttggatgatgcaaatgaatctgaccactttgag
aatatccaatccactaactggcagacaatgaggtttaagcctcctccacctaactctgat
atagggtggcgagtggagtttcgtcctatggaggtccagttaacagactttgaaaactct
gcctatgtagtttttgtggtgttgctgaccagagtaatactttcttacaagttggatttt
cttattccattgtcaaaggttgatgaaaatatgaaaatggcccagaaacgtgatgctgtg
cgtcagggaatgttttactttaaaaaggatatttgtaaagttggcattgctgctgttgac
ggctgttatgcaacacttaatggtacagaagctgagaccgaagaatatactcttatgagt
attgatactataatcaatggcaaggaaggggtttttccaggtttgcttcccattcttaat
tcttacctagaaaacatggaggtagatgtggatacacgctgcaccatactaaactatctc
aaacttatcaagaagcgagcatcaggtgaactgatgacagctgctcgatggatgcgagaa
tttgtatcaaaccatccagactataagcaggacagcgtgatcactgacaaaattaactat
gacttaatggttaaatgtaaccagatagcaaatggacaaacgggttgtccagggctggtt
ggttttacaacttcgaaaacaaatcccagtggaagcaagacgactgtatga
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