KEGG   Nanorana parkeri (Xizang Plateau frog): 108789286
Entry
108789286         CDS       T04897                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
npr  Nanorana parkeri (Xizang Plateau frog)
Pathway
npr00562  Inositol phosphate metabolism
npr01100  Metabolic pathways
npr04020  Calcium signaling pathway
npr04070  Phosphatidylinositol signaling system
npr04081  Hormone signaling
npr04082  Neuroactive ligand signaling
npr04261  Adrenergic signaling in cardiomyocytes
npr04270  Vascular smooth muscle contraction
npr04310  Wnt signaling pathway
npr04371  Apelin signaling pathway
npr04540  Gap junction
npr04621  NOD-like receptor signaling pathway
npr04912  GnRH signaling pathway
npr04916  Melanogenesis
Module
npr_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:npr00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    108789286 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    108789286 (PLCB2)
   04371 Apelin signaling pathway
    108789286 (PLCB2)
   04020 Calcium signaling pathway
    108789286 (PLCB2)
   04070 Phosphatidylinositol signaling system
    108789286 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    108789286 (PLCB2)
   04081 Hormone signaling
    108789286 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    108789286 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    108789286 (PLCB2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    108789286 (PLCB2)
   04916 Melanogenesis
    108789286 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    108789286 (PLCB2)
   04270 Vascular smooth muscle contraction
    108789286 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:npr04131]
    108789286 (PLCB2)
Enzymes [BR:npr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     108789286 (PLCB2)
Membrane trafficking [BR:npr04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    108789286 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    108789286 (PLCB2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 Protoglobin
Other DBs
NCBI-GeneID: 108789286
NCBI-ProteinID: XP_018414761
LinkDB
Position
Unknown
AA seq 1247 aa
MSLFNPILSPADIKPYLTKGERFIKWDDETSIASPVILRVDSKGYYLYWTFQSKEIEFIE
LTSIRDTRFGKYAKIPKSQKLREVFNMDFPENNFLAKTLCVVAGPDMVDLTFHNFVSYKE
NVGKDWASDIMAIVRNPLQINASRYSFYEKIHVKLTLQLNAEGKIPVRNIFQMFPADRKR
VEQALNSCHLSKGKNDAINPEDFPESVYRSFLMQLCPRPEIDEIFTSHHSKAKPYMTKDH
LTKFINQKQRDSRLNELLFPPAKQEQVQTLIEKYEPSAINKQRGQLSPEGMVWFLCGSEN
SVVSLEKIRVHQDMNQPFTHYFINSSHNTYLTAGQFSGISSPEMYRQTLLSGCRCVELDC
WKGKPPEEEPIITHGFTMTTEILFKDVIEAIAESAFKTSSYPIVLSFENHVDSAKQQAKM
ADYCRTIFGDMLLTELLEKFPIKPGCPVPSPNELMGKILIKNKKNQAFTSTEKKAQSGDS
GSSDQTNAQSGENTENETVEEAGGENEGQAVVENVDEEEKQIQSDEGTAGQEVTAYEEMS
SLVNYVQPVKFDSFEVSAQKNQSYVISSFVETKAYDLLTKFPVQFVEYNKRQMSRIYPKG
TRMDSSNYMPQMFWNVGCQMVALNFQTMDLAMQQNMALFEFNGGSGYILKHEFMRQAEKQ
FDPFTVDRIDVVVANTLSITVLSGQFLSDKSVKTYVEVELFGLPGDPKRKYKTKLTSTAN
SINPVWKEEPYVFEKILMPEMASLRVAVFEEGGKFIGHRIIPINVIRSGFHHMCLRSESN
MPLTMPSLFVYVEVKDYIPDTWADLTHALSNPIKAFKAHEKSSIKMNNKGSSIDEKSNSP
QSNGIGGSGKPSVKVTQNGPQGSLGTGKADAVKEAAEPETTNQDELQKQKSFLKLQKKHK
KELKELERKVQKHREEILQKYSSAFSDLNTQLNKKPNRKCQKKKSLEDDYCSIWGAGEIP
GKPDPKIVELKEKMEQELTRASEEFFESIWKKREQHSAEQFSKLLELAQERQATELKVLK
ESTDSDTKLMKKKLEMKRLERLDAMSKNTMDKAAQERLKKEINNSHIQEVVQVLQMISDK
WSNHQQKLEEKQNEGLQKIREKGEQTQKDLQGEYQEKLKSMHGEVAEQIHNCMAPWFPAE
AKSLKKESVNCANTWEFLFARHEKGGTSAENSQQEAKTEEEPAKEVAGEILPNDLASAPM
SKDPTTVEKSESDIHSGDIPAPESSSKAEEEAKDMVGKVPSEKESTQ
NT seq 3744 nt   +upstreamnt  +downstreamnt
atgtctttgttcaatcctattctaagtcctgcagatatcaaaccctacctaaccaaaggg
gaacgcttcatcaaatgggatgatgagacatctatagcatcaccagttattctgcgagtg
gattcaaaaggttattacctgtactggacttttcagagcaaggaaattgaattcattgaa
ttgaccagtatccgagatacgcgatttggaaaatatgccaaaatcccaaagagccagaaa
ttacgggaagtgtttaacatggactttcctgaaaacaacttcttggccaaaactttgtgc
gttgtcgctgggccggatatggtggatcttacctttcacaactttgtgtcctacaaggag
aatgtgggcaaggactgggctagtgacattatggcaatagtcagaaatccccttcaaatc
aatgcgtcacgctactccttttatgagaaaatacatgtaaagcttacacttcagctaaat
gcagagggaaagattcctgtgcgcaacattttccagatgtttcctgcagacaggaagaga
gtggaacaagcattaaattcttgtcatctgtcgaaagggaaaaatgatgccatcaaccct
gaagatttcccagaatctgtctacagatcattcctcatgcagctctgcccccgaccagag
atcgatgaaatctttacctcccaccactccaaagccaagccttatatgacaaaagatcac
cttaccaaattcattaaccagaagcagcgagattcaagattaaatgaattgttgtttcct
cctgctaagcaagaacaagtacaaactctcatagagaaatatgaacctagtgctatcaac
aagcagagagggcagctgtctccggaaggcatggtctggttcttgtgtggctctgagaat
agtgttgtgtcattggaaaaaatacgagtacaccaggacatgaatcagccatttactcac
tactttatcaactcttcacacaacacctacctcacagctggtcagttttcagggatttct
tctcctgaaatgtatagacagaccttgctctcaggctgccgatgcgtggaacttgactgc
tggaagggaaaaccaccagaggaggagccaatcattactcatggcttcaccatgacaact
gagattctttttaaggatgtcattgaagctatagcagaatcagctttcaagacttcttct
tatccaattgtcttgtcctttgagaaccatgtggactctgcaaagcaacaggcaaaaatg
gctgactactgcaggacaatatttggtgacatgctactgactgaattactggagaagttt
cctataaaacctggatgtccagtgccaagccctaatgaactgatgggaaaaatcttaatt
aagaataaaaagaaccaggctttcacttcaacagagaagaaagcacagagtggtgactcc
ggcagttcagatcaaaccaatgcacaatccggtgaaaatacagaaaacgaaacagtggaa
gaagcaggtggagaaaatgaaggtcaagcagtggtggagaatgtggatgaagaagagaaa
cagatccagtctgatgaagggactgctgggcaggaagtcacagcttatgaggagatgtca
agtctagtcaactatgtccagccagtgaaatttgactcatttgaagtttctgcacaaaag
aatcaaagttatgtgatttcttcatttgtggagaccaaagcttatgacctgctgaccaag
ttcccagtgcagtttgttgaatacaataaaagacagatgagtcgtatttatccaaaagga
accagaatggattcatctaactatatgccacaaatgttttggaatgtgggttgtcagatg
gtggcgctgaactttcaaacaatggatttagctatgcaacaaaacatggcactgtttgag
ttcaatggcggcagtggatacattctaaaacatgaattcatgcgacaagcagaaaagcag
tttgacccattcacagttgatcggattgatgtagttgtggccaacactctctcaattaca
gtactctcggggcagttccttagtgacaaatctgtgaagacctacgtagaggtggagcta
tttggactacctggggatcccaagaggaaatacaaaacaaaattaacttcaactgcaaac
tccattaaccctgtgtggaaagaagagccgtatgtgtttgaaaagattcttatgccagag
atggcttctctaagagttgctgtgtttgaagaaggagggaagttcattggtcatcggatt
attccaatcaatgtgatcagatcaggttttcaccacatgtgtcttcggagtgaaagtaac
atgccgctcaccatgccctctttgtttgtgtacgtggaggtgaaagactacataccggat
acatgggcagatctcactcatgctctgtccaatcctataaaagctttcaaagcacatgag
aaatcatcaataaagatgaacaacaaaggatcctccattgatgagaaatccaacagtcct
caatcaaatggcattggtggttctggcaaaccatctgttaaagtaacacagaatggtcct
caagggtctttgggaactggaaaagcagatgctgtgaaagaagcagcagaaccagaaacc
acaaaccaagatgaactgcagaaacagaagagcttcttgaagcttcagaagaaacacaag
aaggagctgaaagaactagaacggaaggtacagaaacacagagaagagattctccagaaa
tactccagcgcctttagtgatttgaacacacagctcaacaagaaacccaaccgaaagtgt
cagaaaaaaaaaagtctggaggatgactattgttccatatggggtgctggagaaatccct
ggaaaaccagatccaaaaatagtggagctgaaggagaagatggagcaggaactgacacgt
gcttctgaggagttttttgagagcatttggaaaaagagggagcaacattctgcagaacaa
ttcagcaagttgttagagctagcccaggagagacaggcaacagaactaaaagtcctgaaa
gaatctacagacagtgacactaaactgatgaagaagaagttggaaatgaagcggctggag
aggcttgacgcaatgagtaagaatacaatggacaaagctgctcaggagaggttaaaaaag
gaaataaacaactcacacatccaggaggtggtgcaggtcttgcaaatgatatctgataaa
tggagcaaccatcaacagaaactagaagaaaaacagaatgagggtctccagaaaatcaga
gagaaaggagaacagactcagaaagatcttcaaggagaataccaagaaaaattaaagagc
atgcatggggaagtggcagaacagatacataactgcatggcaccatggtttccagcagag
gccaaaagccttaagaaagagtcagtaaactgtgcaaacacgtgggaatttctctttgca
agacacgagaaaggaggtacttctgctgaaaacagtcaacaggaagcaaaaacagaagaa
gaaccagcaaaagaggtggcaggggagattttaccaaatgaccttgctagtgcacctatg
tctaaagaccctacaactgttgagaagtctgaaagtgacatacattctggtgatattcca
gcaccagaatcatcttctaaagctgaagaagaggcaaaggatatggtgggaaaggtccct
tctgaaaaggaatctacacagtaa

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