Neodiprion pinetum (white pine sawfly): 124223913 Help Entry 124223913         CDS       T08966                                  Symbol RyR Name (RefSeq) ryanodine receptor isoform X1   KO K04962   ryanodine receptor 2 Organism npt  Neodiprion pinetum (white pine sawfly) Brite KEGG Orthology (KO) [BR:npt00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:npt04040]     124223913 (RyR)    04990 Domain-containing proteins not elsewhere classified [BR:npt04990]     124223913 (RyR) Ion channels [BR:npt04040]  Voltage-gated cation channels   Ryanodine receptor    124223913 (RyR) Domain-containing proteins not elsewhere classified [BR:npt04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    124223913 (RyR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 baeRF_family6 Motif Other DBs NCBI-GeneID:  124223913 NCBI-ProteinID:  XP_046492257 LinkDB All DBs Position 7:26383136..26418359 Genome browser AA seq 5128 aa AA seqDB search MADSEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDLS QCVFVIEQALSVRALQELVTAAGSETQQESLGKGTGSGHRTLLYGNAILLRHQNSDMYLA CLSTSSSHDKLAFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYL HTTKENDLSVVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTW STAPGQNMVIYEGGSVMSQARSLWRLELARTKWAGGFINWSHPMRIRHLTTGRYLGVNEN NELYLVGRNEATIETSTFWLQSEKTDTKTILEDKDLEIIGTPIIKYGDSTVIMQHATKGL WVSYKSYETKKKGVGKVEEKQAVLHEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTQF ITGLETLQMDRRASMFFQNVNLNEMVMCLEDLINYFAQPEEDMEHEEKQNRLRALRNRQD LFQEEGILNLILEAIDKINVITSQGFLVALSGDESGQSWDQISGYLYQLLAAIIKGNHTN CAQFANSNRLNWLFSRLGSQASGEGTGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEK HGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTQLVDHVASIRPNIFVGR VEGSALYQKWYFEVTVDHIEQTTHMMPHLRIGWANTAGYTPYPGGGEKWGGNGVGDDLYS FGFDGAYLWSGGRKTQIVQDATEPYIKKGDVIGCTLDLTIPVITFAFNGMHLKGSFRDFN LDGMFFPAISCSSKLSCRFLLGGDHGRLKFQPPDDFSPLVESLLPQQILSLDPCFYFGNM NKVVLAGPWLVEDDTAFVPTPVDTAMINLPAYIEQIRDKLAENIHEMWAMNKVEAGWIFG EQRDDLRKIHPCIIQFERLPAAEKRYDTQLAVQTLKTILALGYYITMDKPPSRIKTLRLP NEPFMQSNGYKPAPLDLSAITLTPKMEELVDQLAENTHNLWAKERISQGWTYGLNEDSEM RRSPHLVPYFKVDEAIKKANRDTASETVRTLLVYGYMLDPPTGEQHEALLLEASRLRQLL FRTYRVEKNYAVASGKWYFEFEVLTAGPMRVGWAKSDCMPGSMLGSDENTWAFDGYNVTK VHCGSNESFGHKYQVGDVVGCFIDVQDGTISFSLNGELLMDALGGETSFADVQGDSFVPA FTLGVGQKAKLTFGQDVNTLKFFTTCGLQEGYEPFCVNMNRPVTFWYTKDQPIFENTDDM ADTRIDVARIPAGSDTPPCLKISHNTFETMEKANWEFLRLSLPVICQSSFITEGEKLRRW QEIKMRQNRLLVEQSEQTQGTSQSAHMEQIIKSGFSMSDIKGLQRNYSEDAVEADEIMKE SPLPMQRMKPSRPPRKGSLSRSNMYGSRGGTLERATSEAEVNGYGDMNGDLKDDKKKRGR SPFRFFSRKTKSPEAKSKTPEPPMRSDISDRSSKPLPFVRVGSRPAQVRVSTTDLKVVPP QIPERNAPKQMSVLSGTGVEAIGNEIYDADCLKLMNEYFYGVRIFPGQDPTHVYVGWVTS QYHLHTKDFNLSRVRKSSIVIVDDYDRPLEQVDRQSCYMVRADELYNEVTQDASGKGASQ GMFVGCFVDIATGWVSFTCEGKETSHKFKMEPDTKLFPAIFVEATSREILQIELGRTSTT LPLSAAVLQNSERHVIPQFPPRLKVQCLKPHQWARVPNQSLQVHALKLSDIRGWSMLCED AISMLALHIPEEDRCIDILELIEMDKLLSFHAHTLTLYAALCYQSNYRAAHALCLHVDQK QLLYAIRSEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEFIIPLGQEIKDLYEDPDMK HSLRYLETESVRPQMKMTDIEVLPSSENQSIENIRNLYSPYFPLDVVRNYVMMALNEAVE VNQVHNRDPIGGSNENLFLPLLKLVDRLLLVGMLRNEDIFKLLIMINPETWDPTFEKEGK DEHKKGLLHMKMAEGAKLQMCYLLHHLNDIQLRHRVESIISFSHDFVGDLQSDQLRRYID IKQSDLPSAVAAKKTKEFRCPPREQMNAILGFKNLDEEEKENCPCGEELREKMNEFHDEL MSYVSLHALQEAADAANEIIEIEKPGAMKRVFNFINAVKEFEEEPKLEPEPVKKTPEEVF RKVLIATIVKWAEESQIETPKLVREMFSLLVRQYDTVGELIRALEKTYIINSKTKEDVAE MWVGLSQIRALLPVQMSQEEEELVRERLWKLVNNHTFFQHPDLIRVLRIHENVMAIMMNT LGRRAQAQSDAQAQSQAAEGEAAAKEKDTSHEMVVACCRFLCYFCRTSRQNQKAMFDHFD FLLENSNILLSRPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAIYLSRCGLQSNSE LVEKGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENANLVIRLLIRRPECLGPALRGEG EGLLRAIMEANKMSERIADRRKVQDETEGTAMVIQFEHPLPESDDDEDYIDTGAAILNFY CTLVDLLGRCAPDSSVIEQGKNESLRARAILRSLVPLDDLQGVLSLRFTLQNPAAGEERP KSDMPSGLIPGHKQSIVLFLERVYGIETQELFFKLLEEAFLPDLRAATMLDRNDGYESDM ALAMNRYIGNSILPLLIKHSKFYNEADNYASLLDATLHTVYRLSKNRMLTKGQREAVSDF LVALTSQMQPSMLLKLLRKLTVDVSKLSEYTTVALRLLTLHYDRCAKYYGSTSGQGAYGA SSDEEKRLTMVLFSNIFDSLSKMDYDPELFGKALPCLTAIGCALPPDYSLSKNYDDEWYG SKSASTQSPDGPYNPQPINTSSVVLNNDLNSIVQKFSEHYHDAWANRKLENSWTYGEQWS DLNKTHPRLKPYNLLNDYEKERYKEPVRESLKALLAIGWSVEHSEVDVPSTSRSSMRRSS KSQADAANPFNYNPHPVDMTNLTLSREMQNMAERLADNAHDIWAKKKKEELITCGGGIHP QLVPYDLLTDKEKRKDRERSQEFLKYLQYQGYKLHKPVRSSTADTEVAGVGAAVELRFAY SLLEKLIAYLDKATINMKLLKPSDTFSRRNSFKTSTRDIKFFSKVVLPLMEKYFSTHRNY FIAVATATNNIGAASLKEKEMVAALFCKLASLLRSRLAAFGADVRITVRCLQVLVKGIDA KSLVKNCPEFIRTSMLTFFNNTADDLGHTIGNLQEGKYSHLRGTHLKTSTSLSYVNSVVL PVLTSMFDHLAACEYGSDLLLDEIQVASYKMLASLYTLGIDATLTHDRKYLKTEIERNKP NLGSCLGAFSSCFPVAFLEPHLNKHNQFSLLNRIADHSLEAQDIMSRMESSMPTLETILT EVDQFVESEKTYSDAPHVIDVILPLLCSYLPFWWAQGPDNVNPNEGTYVSMVTSDHMNQL LKNVLKLIKKNIGNENAPWMTRIAAYTQQIIINSSEELLKDPFLPLAERVKKRTDNMFHK EESLRGFIKSSTDDTSQIEAQIQEDWQLLVRDIYSFYPLLIKYVDLQRNHWLRNNIPEAE DLYNHVAAIFNTWSKSQYFLREEQNFISANEIDNMVLIMPTATRRPTAVSDGTTPSGGGK KKKKHRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRFLKKLPEYEI TEFATTQLTLPDKIDPADEMSWQHYLYSKLGQKKDVTEPVKAQQLDDVVTRIVAMAKVLY GLHMIDHPQQQSKSSYRSVVSIQRKRAVIACFRQTSLHSLPRHRAINIFARTYYELWLQD ENVGQEVMIEDLTQSFEDAELKKMDKTEEEGKPDPLTQLVTTFCRGAMTERSGALQEDPL YMSYAQIVSKSCGEEEEEGEDEGGGEEEGAASIHRPMHKLMEQEMEKQKLLFHQARLANR GVAEMVLLHISACKGVPSEMVMKTLELGISILRGGNIEIQKGMLNHLKEKKDVGFFTSIA GLMNSCSVLDLDAFERNTKAEGLGVGSEGAAGEKNMHDAEFTCALFRFIQLTCEGHNLDW QNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKELIDPAGKANFFKAIEVAS QVFNTLTEVIQGPCAQNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDLLKELLNL QKDMITMMLSMLEGNVVNGTIGKQMVDTLVESAGNVELILKYFDMFLKLKDLISSPSFLE VDVNNDGWVYPKDFKEKMEQQKSYTIEEIEFLLACCETNHDGKIDYVAFMDRFHEPAKEI GFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEILGGSRKIERVYFEIKE SNIEQWEKPQIKESKRAFFYNTVTEGGDKEKLETFINFCEDAIFEMQHASALMAVEESSG IGKARESSYTYMTEDDDERNKDPIRRGIQAFKDGVYFFFSMFSPTNIKNKFSEMQQMTIP ELFVGFFKMIFYAFYYSGFGVGCVIRYFMRLLLSLMRGPHIDEPIVEIKEEEEKPLRLLP ALPPTPDDSNLQVQAFGMDITKEEGGQIKLAPHESAASTPQSSMEETGESTQDEGVGEDH PRGSVDGIATETEGPVTLADLLGGEQARAQAAATAEAAAAQQAAMAAVEAEAKQETAIEP SAGSSIDLSEYTHRIVSFLARNFYNLKYVALVLAFCINFMLLFYKVTSLGEEENGSGSGD PIADLLAEISGEGSSDGDGSGGDGGSGGSNGSSEEEEDPLELVEVSEDFYYMAHVMRLMA AMHSIVSLAMLVAYYHLKVPLAIFKREKEIARRVEFDGLYIAETPEEDDIKAHWDKMVIS AKSFPVNYWDKFVKKKVRQKYSETYDFDYISNLLGMEKTSFSQQEEEGSGLLHFIINIDW RYQVWKAGVTITDNAFLYSLWYFTFSILGNYNNFFFAAHLLDVAVGFKTLRTILQSVTHN GKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDDEVDKKCHDMLTCFVFHLYKGVRAG GGIGDEIGEPDGDDYEVYRIMFDITFFFFVIVILLAIIQGLIIDAFGELRDQLESVKDNM ESNCFICGLGKEYFDTVPHGFDTHVQQEHNLANYMFFLMHLINKPDTEYTGQETYVWNMY QQRCWDFFPVGDCFRKQNEAVEEEAKKK NT seq 15387 nt NT seq  +upstreamnt  +downstreamnt atggcggacagcgagggtggctccgagcaggatgacgtctccttcctccggacggaggac atggtgtgcctgtcctgcacagccaccggtgaaagggtctgcttggcggcggaaggtttt ggaaacagacattgtttcctcgaaaacatagccgacaagaatattccaccagacttatcg caatgcgtctttgtaatagaacaggcgctgtccgtacgagcgttgcaggaattggtcacc gcagcaggttccgaaacgcagcaagagtctttagggaagggtacaggatctggtcacaga actttgctctacggcaatgcaattctgctcaggcatcaaaacagtgacatgtatctggcg tgcttgtccaccagttcgtctcacgacaaacttgcatttgatgtcggtttgcaagaacat tctcaaggagaggcttgttggtggacggttcatccggcttccaagcaaagatcagagggt gagaaggtccgagtgggtgacgatctcattttagtatcagtcgctaccgagcgatacttg cacacgacgaaggagaacgacttgtctgtggttaatgcctcatttcacgttacacactgg tcagtgcaaccatacggcactggcataagccgaatgaaatatgtcggctatgtcttcggc ggcgatgtattgagattcttccacggaggtgacgaatgtcttactataccatccacatgg agcaccgcacctggccaaaacatggttatctacgaaggaggaagcgtaatgagccaagcg cgatctttgtggagattggagttggccagaacgaaatgggctggtggttttattaattgg tcacatcccatgcgtatcaggcatcttaccacaggccgttatttgggtgttaatgagaat aacgaattatatttggtgggccggaacgaggctacaatagagacctcgacattctggctc caatcagagaaaacagatacgaaaactattctcgaggataaggatttggaaataatcgga acaccgatcatcaaatacggtgactccacagtgattatgcagcacgcaaccaagggtctc tgggtctcgtataagtcctacgaaaccaagaaaaaaggcgtgggtaaagtcgaagaaaag caggcggtactgcacgaggaaggaaaaatggacgacggacttgacttctctcggtctcaa gaagaggagtcaaggacagctcgggttatcaggaaatgcagcagtctgttcacgcagttt attactggcttagaaactcttcaaatggatagaagagcctcaatgttctttcagaatgtg aatttgaacgaaatggtcatgtgcttggaagatctgatcaactactttgctcagccggaa gaagatatggaacacgaagaaaaacaaaatagactacgggccttgagaaatcgtcaagat ttattccaggaggaaggaattttgaatctaatcctcgaggctatagacaaaatcaatgta ataacttcgcaaggttttctggtcgcactttccggtgacgagagtggccagtcttgggat caaatttctggttacctctatcaactgcttgctgctatcattaagggaaatcacacgaac tgcgcccagtttgcgaacagcaatcgtcttaactggctgttcagtcgtctgggatcgcag gcgtctggcgaaggaacaggaatgctggatgtgcttcattgtgtccttatagattccccc gaggctttaaacatgatgagagatgagcatatcaaagtgataatatctttgctggaaaag cacggcagggatcctaaggttcttgacgtattgtgttctctgtgcgttggtaacggagtt gcggtacgatcgtcacagaataatatatgtgattttctgctaccggggaaaaacttgctg ctacaaactcagctagtcgatcacgtggccagtataagaccaaacatattcgttggcaga gtcgaaggttcggctctctatcaaaagtggtactttgaagttaccgttgatcatattgaa caaacaacgcatatgatgcctcatctcagaatcggttgggccaatacagctgggtacacg ccgtatccaggcggtggtgaaaagtggggcggcaacggagttggagacgatttgtactcc tttggatttgacggtgcttatctttggtcgggcggtagaaaaacgcaaatagtacaggac gcgacggaaccttacataaaaaagggggacgtcattggatgcactttggacttgaccatt ccagtaataacctttgcgttcaacggaatgcacctcaagggatctttccgcgacttcaac ctggatggaatgttctttccggcaataagttgctcctcaaaattatcatgcagatttctt ttgggtggtgatcacggacgcctcaagtttcaacctccggacgatttctcgccactggtc gaaagtctattgccgcaacagattctctctctggacccttgcttctactttggtaacatg aacaaagtggtccttgccgggccttggctagttgaggacgacacggcatttgtaccaaca cccgtagacacagccatgatcaatctacccgcttatatcgaacagataagagacaagctg gcggagaatatccacgagatgtgggctatgaataaagttgaagctggctggatattcggg gaacaaagagacgatcttagaaaaatacatccgtgtattatccagtttgaaagacttccg gcggcagagaaacgctacgatactcagctggccgtacagaccttgaaaactatcctggct ctcggttattacatcaccatggacaagccaccgtctagaataaaaaccttacggctgccc aacgaaccgttcatgcaatcgaacggttataagccagctccactagacctgagcgcaatc acattgacaccaaagatggaggaactcgtagatcaactggccgaaaatactcataacttg tgggcaaaggagaggatcagtcagggatggacgtacgggttgaacgaggattccgaaatg aggcggagtccgcatttagtaccttatttcaaggttgacgaagcgataaagaaagcgaac cgggacacagccagcgaaactgtcagaacactgctcgtttatgggtacatgctcgaccca ccaacgggagagcagcacgaagctttgctcttggaggccagcagattacggcaacttttg ttcagaacatacagggtggaaaaaaattacgccgtcgccagtggaaagtggtattttgaa ttcgaagtgctcactgctggacccatgcgagtaggttgggcaaaatccgattgcatgcct ggtagcatgctcggtagcgatgaaaatacctgggctttcgacggatacaacgtgaccaaa gtccactgtggttcgaacgagtctttcggtcacaaatatcaagtgggtgacgtagttggc tgtttcattgatgtccaagacggaacgatcagtttttcattaaacggcgagctgctaatg gacgcccttggtggggagacatcgtttgcagatgttcaaggcgattcgttcgtgccagcc tttacgcttggggttggacaaaaagctaaattaacattcggccaagacgtgaatacattg aaatttttcacaacctgtggactgcaagaaggctatgaacccttctgcgtaaacatgaat cgtcccgttactttctggtataccaaagatcagccaatctttgaaaatacagacgacatg gctgacacaaggattgacgtggctcgaattccggctggttccgacacaccgccttgtctg aaaatctcgcacaacacttttgagactatggagaaagccaactgggaatttttgagacta tcgctgcccgttatttgccaatcaagtttcataaccgaaggagagaaactgcgacgatgg caagagataaaaatgcgtcagaacagacttctcgttgaacagtccgagcaaactcagggg acttcccagtcagcgcacatggagcaaataatcaagtccggattcagcatgagtgacatc aagggccttcaaagaaattattcggaagatgcggtcgaagctgatgaaattatgaaggaa tctccgcttccgatgcaacgaatgaagccttccagacccccgaggaaagggtctttatcc cggtccaacatgtatgggtcgagaggcggaactttggaaagagccacaagcgaagccgag gtgaatggttacggagacatgaacggggacctcaaggacgacaagaagaagagggggcga tcacctttccggttcttctctcgcaaaacaaaatcaccggaagcaaaatcgaaaactccg gaacccccgatgaggtcagatatttcggacagaagcagtaagcctttgccatttgttagg gtagggtcgagaccggctcaagttagagtctccactaccgatttgaaagtggtaccccca caaattccggaacgcaacgcgccgaagcaaatgtctgttctctctgggacgggagtcgaa gcaattggaaatgaaatatacgatgcggattgcttgaaattgatgaacgaatacttttat ggagtaagaatattccctggtcaagatccaactcatgtttatgtcggatgggtaacttcg cagtatcatttgcatacaaaagatttcaacctatcgagagttagaaaatcgtcaattgta atcgtggacgactacgacagaccgttagagcaggttgatcgtcagagctgctacatggtg agagccgacgagctttacaacgaagtgactcaagatgcttctggtaaaggtgcttcgcaa ggcatgttcgttgggtgttttgtcgacatagccaccggctgggtgtccttcacctgcgaa ggaaaagaaacgagtcacaagtttaaaatggaaccggacacaaagttattcccagctatt ttcgttgaggcaacaagcagagaaatacttcaaatagaattgggaagaacgtctactacg ttgccgttgtcagctgctgttttacaaaactcggagcgtcatgtgattcctcagttcccg cccagattgaaagtgcaatgtcttaagcctcatcagtgggccagggtacccaatcaatcc ctccaagtgcatgcgctcaagctatccgatataaggggatggtcgatgttgtgcgaagat gcaatttcgatgcttgctttgcatattccggaagaggacagatgcatcgatattcttgaa ctaattgaaatggacaaacttctaagctttcacgcccatacgctcacactatatgcagcg ttgtgctatcaatcgaattatagagcagcacatgctctctgtttgcatgtggatcagaag caattactctatgctattcggtccgaatatatgtccggtccgcttcgacaaggtttttat gatctgttaattgcattgcatctcgagtctcatgccacaactatggaagtttgtaagaac gagttcatcattccattagggcaagaaataaaggatctctacgaagatcctgacatgaag cacagcttgagatacttggaaactgaatcggtccggccacagatgaaaatgaccgacatc gaggtacttccttccagtgaaaatcagagcatcgaaaatattagaaacttgtacagtccg tatttcccacttgatgtggttcgtaattacgttatgatggccctcaatgaagcagtggaa gttaatcaagtccataatcgagatcctattggaggcagcaatgaaaatttatttctacca ctcttaaaacttgtggacagactactacttgttggaatgctcaggaatgaagatattttc aaattgctcataatgattaatccagagacctgggatccgacttttgaaaaagagggaaaa gatgaacataagaaaggattgctacacatgaagatggccgaaggcgcaaaattgcaaatg tgctacctgctgcaccatttgaatgatatccagcttcggcatcgtgtcgagtcaataatt tcctttagtcacgattttgttggtgatcttcagtccgatcaactccggcgttatattgat attaaacagtctgaccttccatcggctgtagcggcaaagaaaactaaagagttcagatgt ccgcctcgcgaacaaatgaatgctattttaggattcaaaaatttagacgaggaagagaaa gaaaactgtccgtgtggtgaagaattgagggagaaaatgaacgaatttcacgatgagttg atgtcctacgtgtcgctccatgcactgcaggaggcggctgatgctgcaaatgaaataata gaaatcgagaagccaggagctatgaaacgggttttcaatttcataaatgccgtcaaagaa tttgaggaagagccgaaacttgaaccggaacctgtcaagaaaaccccggaagaggtattt cgcaaagtactcatagcaacgatagtcaaatgggcagaagaatcgcaaattgaaacaccg aagctagtccgtgaaatgttcagtttattggtacgccagtacgataccgttggcgaattg attcgagcgttagaaaagacgtatataatcaatagcaagacaaaggaagatgttgctgaa atgtgggtgggtttgagtcaaatccgtgcattgctgcctgttcaaatgtctcaggaagaa gaggaactggttcgtgaacgtctttggaagctcgtgaacaatcacacgttcttccaacat cccgacttgattcgcgtgctgagaattcacgagaacgtaatggcgataatgatgaataca ctgggaagacgagcccaagcccagtccgatgctcaggcacagagtcaggctgccgaggga gaggcggccgccaaagaaaaagatacttcccacgaaatggtggtggcatgttgccgattt ctttgctatttctgccgcacctcgaggcaaaatcagaaagctatgtttgatcattttgat ttcttgctcgagaacagtaatatccttctatcgagaccttcgctaagggggtcaacgcca ctcgacgtggcatattcttcgctgatggaaaataccgaacttgctctcgcactcagagag cattaccttgaaaagatcgctatttatttatctcgctgtggactgcaatcaaattccgag ttagttgaaaagggatatccagatcttggttgggatccagtcgagggtgaacgttaccta gacttcttgcgcttctgtgtttgggtcaatggtgaaagtgtcgaagaaaatgctaacttg gtgataagattgctcattcggcggccagaatgcttgggtcctgcgcttcgcggagaagga gaaggtctgttgagagctatcatggaggcaaataaaatgtccgagcgtatcgcggatcgt agaaaggttcaagacgaaacggaaggaacagctatggttattcagtttgagcaccctctt cccgagtcggacgatgacgaagattacatcgataccggagcagccattctgaacttttat tgtaccttagtagatctcttgggacgctgtgctccagattcttctgtcatagaacaagga aaaaacgaatccctccgagcaagagctattttgcgttctcttgtcccacttgacgatcta caaggtgttctttcactccgatttacactgcaaaatcctgccgctggcgaggaaagacct aagagtgacatgccgtctggattaattccggggcacaagcagagtatagtgttatttttg gaacgtgtttatgggattgaaacgcaggaacttttcttcaaattactcgaagaagctttt ttgcctgaccttagggctgctaccatgctggataggaatgacggctacgaatctgatatg gctttagctatgaatcgatacataggaaacagtatactaccactcctcataaaacattct aagttctacaatgaagccgataactatgcgagtttattagatgctacgttgcataccgtg tatcgtctcagtaagaacaggatgttaaccaagggacagcgtgaagctgtttctgatttt ctcgtggcattgaccagccaaatgcaaccgagtatgttgctgaagctccttcgaaagttg accgtcgatgtttcgaaattgtcggaatatacaacagtagctttaaggctgctgacatta cattacgaccgctgtgctaaatactacggctcgacaagcggtcaaggagcttacggagct tcaagcgacgaagagaaacgtctgacaatggtcttgttcagtaacatattcgactcatta tccaaaatggattatgatccggaattgttcggtaaggcgttgccttgtttgactgccatc ggttgtgccttacctcccgactattcgttatcgaaaaattatgacgacgaatggtacggg agcaagtctgcctcgacacaatctccggacggaccatataatccgcagccgatcaacacg tccagtgtcgtgctgaacaatgatttgaattcgatagtacaaaagttttctgagcactat cacgatgcttgggctaatagaaagctagaaaatagctggacgtacggtgaacagtggtct gatctaaacaagacacatcctagactgaagccttacaatttgcttaatgattatgaaaaa gaacgctataaggaacccgtcagggaaagtttgaaggcactgcttgctattgggtggagc gttgaacactccgaagtggacgtaccttctacaagtcgtagctctatgagaaggtcgtct aagagccaagcagacgcagcgaatccgttcaactacaaccctcatcccgttgacatgacc aacctgacactcagtagagaaatgcaaaatatggctgagcgtttggctgacaacgctcat gacatttgggctaaaaagaagaaggaggagctcatcacttgcggaggtggtattcaccca cagctggtgccttacgacttgttgaccgacaaagagaaacgcaaggatcgtgaacgctcc caagagttcttgaaatatctacaatatcaaggatacaaattgcacaagccagttcgcagt agtacggcggatacggaagttgccggggtcggagcagctgtagaattacgattcgcgtat tccttgcttgagaaattgatagcgtatttggataaagctactatcaacatgaagttgttg aagccttcggacacctttagcaggaggaacagtttcaaaacatcgacaagagatataaag tttttcagtaaagtggtcctaccattgatggaaaagtacttcagtactcacagaaattac tttatcgccgtggccactgcgacaaataacataggagctgcgtcactgaaagaaaaagaa atggttgctgcgttattttgcaagctggcgagtttgctccgatcacgattagctgcattc ggggcagatgttagaataacggttcgatgtctgcaagtgttggtcaaaggtatcgacgcg aaatcgcttgtaaaaaattgtccagaatttatcagaacgtcgatgttaacatttttcaac aatacggccgatgacttgggacataccataggcaatttgcaagaaggaaaatacagtcat cttagaggaacgcacttgaaaacatcgacttctttgtcttatgtgaacagcgttgtttta cccgtcctcacctccatgttcgatcacttagcggcttgcgaatacggcagtgacttgttg ctggacgagattcaagttgcctcgtacaaaatgctggcatctctttatacgttgggtatc gacgctactctaacccacgatcggaagtatttgaaaactgaaatcgaacggaacaaacct aatcttggttcttgccttggagccttctccagctgcttcccagttgccttcctagagccc cacttgaacaagcacaaccagttttcgctattaaatagaatcgccgatcactccctcgag gctcaagatataatgtctcggatggaatcgagtatgcctacgttagaaacgatcttgacc gaggtagatcagtttgtggaatcggaaaaaacttatagcgacgcccctcacgttatcgat gtcatactaccattgctttgctcgtacttgcctttctggtgggctcaaggtccagacaac gtcaatccgaatgagggaacgtacgtgagcatggttacgagtgaccacatgaaccagctc ttgaaaaatgtgttgaaattgatcaaaaagaacatcggaaacgagaatgctccgtggatg acacgcatcgcggcttacacgcaacaaattatcattaattcatctgaagagctgctcaag gatccgttcttgccacttgctgaacgtgttaaaaagcggaccgacaacatgttccacaag gaggaatcgttgcgtggctttatcaagtcgtcaacggacgatacgtctcagatagaagca caaattcaggaagactggcaactccttgtcagagatatatattcgttttacccgctgctt attaagtatgtcgatttacaacgtaatcattggctgcgtaacaacataccggaagccgaa gacctttataatcacgttgcagcaatattcaatacctggtctaagtcacagtacttttta cgcgaagaacagaactttatatcagccaatgaaattgacaatatggttcttatcatgcct acggctaccagaagaccgacggctgtttccgatggcacaactccgtccggtggtggaaag aaaaagaagaaacatcgggacaaaaaacgagacaaagacaaggaagtacaggcgtcgctg atggttgcttgcctgaaacgattgttgcctgttggcttgaacttgtttgcaggacgagaa caggaactcgtccagcattgtaaggataggtttttaaagaaacttcctgaatatgaaatc actgagttcgctacaacgcagcttactttgccggacaaaatcgatccggctgatgaaatg tcttggcaacattacctgtattcaaagcttgggcaaaaaaaagatgtgaccgaaccggtc aaggctcaacaactcgacgatgtagttactagaattgtggcaatggccaaagtgctttac gggcttcacatgatagaccatccccagcagcagagcaagagtagctatcgctcggtggtg tctatacagagaaagcgagcagttattgcttgcttccgtcagacctccctacattcctta cccaggcatcgggcaatcaatatctttgcaagaacttattacgaactctggctgcaagac gagaatgtgggacaagaagttatgattgaagatctaacgcaatcattcgaagatgcagaa ttgaaaaagatggataagacggaagaggagggtaaacctgatcctttaacgcaactagtt acaacgttctgtcgcggagccatgactgaacgttcaggagctcttcaagaagatcccctc tacatgagttatgcgcaaatagtatcaaaatcttgcggggaggaagaagaggaaggcgaa gatgagggagggggcgaggaggaaggcgcggcatcaattcataggcctatgcacaaactc atggaacaagaaatggagaaacagaagctgttgtttcatcaagctcgtcttgcaaatcga ggagttgcagaaatggtattgctgcatatttcggcttgcaagggtgtcccaagcgagatg gtcatgaaaactttagagctgggcatttcaattctacgaggtggtaacatcgagattcag aaggggatgctgaaccatttgaaagagaaaaaagatgttggatttttcacctcaattgct ggattaatgaattcgtgtagcgtactagatctcgatgctttcgaaagaaacacaaaggca gaaggtctgggagtcgggtctgaaggtgctgcgggtgaaaaaaatatgcatgatgctgaa ttcacctgtgcgttgttcaggtttattcaactgacttgcgaagggcacaatttagactgg cagaattacttgagaacccaagctggcaacacaacgacggtgaacgtagtcatatgcact gtggattacctccttcgtctccaggagtcaatcatggacttttactggcactactccagc aaggaactcatagatccagctggaaaagcaaacttcttcaaggctatcgaagtcgcaagt caagtattcaacaccctgactgaagttattcaaggtccttgcgctcagaaccaacaagct ttggcacactctaggctttgggatgccgtgggaggatttctgtttctcttttcacatatg caggacaaactttccaagcattctagccaagtagatcttctcaaagaattactaaatctg caaaaggacatgatcacgatgatgctgtctatgttagaaggtaacgttgtaaacggcacc attggaaagcagatggtggatacgctcgtggaatctgctggaaatgttgaattaattttg aaatactttgacatgttcctcaagttaaaggatcttatatcttcgcccagcttcctcgaa gttgacgtcaataacgacggatgggtatatccgaaagactttaaggaaaagatggaacaa caaaaaagttataccatcgaggaaatcgaattcttactagcttgttgcgaaacaaatcac gacggcaaaattgattatgttgcatttatggatcgttttcacgagcctgctaaagagatt ggcttcaacctcgctgttctgttgacaaatttgtcagaacatatgccaaacgagccaagg cttgcacgttttcttgaaacagcaggttctgtgctcaattactttgaaccgttcctgggg cgaatagaaattctcggcggtagtagaaaaatcgagcgtgtttactttgaaatcaaagaa tccaatatcgagcagtgggaaaaaccgcagatcaaagaatcgaaacgagcgttcttctac aatacagtaaccgaaggaggtgacaaagagaaattggagacatttattaatttttgcgaa gatgctatatttgaaatgcagcacgcaagtgccttgatggctgtcgaagagagcagcggt atcggaaaagcaagagaatcatcttacacctacatgacggaagatgacgatgaaagaaac aaggatccgatccgaaggggaattcaggctttcaaagacggagtttatttcttcttctca atgttctctccgaccaacataaagaacaaattttccgaaatgcagcaaatgacaatcccg gaattgtttgttggcttctttaaaatgattttctatgcattctactactctggatttggc gtcggctgcgttatcagatacttcatgagattattgctcagtttaatgagaggaccgcac attgacgaaccgatagttgagatcaaggaagaagaagaaaaaccgttacggctactacca gccttaccgccaacgcccgatgattcaaatttacaggtccaggcgtttggaatggatata acgaaagaagaaggtggtcaaattaaactagctccccacgaatctgccgcttctacacct cagtcaagtatggaagaaacgggtgagagtacgcaagacgaaggagtcggcgaagatcat cctcgaggatcagtggacggaattgctaccgaaacggaaggacctgtgacattggcagac ttattaggaggagaacaagccagagcacaagcagcagctacagccgaggcggcagcagct cagcaagctgcaatggcagctgtcgaggcagaggcgaaacaagaaactgcaatcgaaccc tcagctggctcaagtatcgacctttccgaatacactcaccgcattgtgtctttcctagcg 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aaatgtcacgacatgttaacgtgctttgtattccatctgtacaaaggagtgagagccggt ggcggtattggtgatgaaattggagaacccgacggcgatgactatgaagtctatcgtata atgtttgatatcacgttcttcttctttgtcattgttatcctgcttgctattattcaaggt ttgatcatcgacgcgttcggagagttgcgtgatcagcttgaaagtgtcaaagacaacatg gaaagcaactgttttatatgtggtttgggaaaagagtacttcgatacagtgcctcatggt tttgatacacacgtccagcaggaacataatttagcaaattacatgttcttcctcatgcat ctgattaataaaccggatacagaatacactggtcaagagacgtacgtttggaatatgtat caacaaaggtgttgggatttcttcccagtgggtgattgcttccgaaagcagaacgaggct gttgaggaggaagccaaaaagaaatga

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