Novosphingobium resinovorum: BES08_05315
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Entry
BES08_05315 CDS
T04490
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
nre
Novosphingobium resinovorum
Pathway
nre00290
Valine, leucine and isoleucine biosynthesis
nre00620
Pyruvate metabolism
nre01100
Metabolic pathways
nre01110
Biosynthesis of secondary metabolites
nre01210
2-Oxocarboxylic acid metabolism
nre01230
Biosynthesis of amino acids
Module
nre_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
nre00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BES08_05315
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BES08_05315
Enzymes [BR:
nre01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BES08_05315
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AOR76242
UniProt:
A0A031JZU0
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All DBs
Position
1165204..1166871
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AA seq
555 aa
AA seq
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MTMLKDPSVKYRPFPQIDLPNRQWPSQVITKAPRWLSTDLRDGNQALIDPMGAEKKSRFF
DLLVKVGLKEIEVGFPSAGATEFDFIRGLVDQDRIPEDVLVQVLTQSRQDLIERTFESLA
GVHAGIVHLYNAVSPLWRNVVFGMERHEIRGIAETGAKIMRDQAAKYPQTKWHFEYSPET
FSTAELDFSIECCEAVMEILQPTPENPIILNLPATVEAATPNIYADQIEYFCRNLPNRDA
AVISLHTHNDRGTGVAAAELGLMAGADRVEGCLFGNGERTGNCCLVTVAMNMYTQGVNPE
LDFSDIDDVIQTVEYCNQLKVAERHPYGGELVFTAFSGSHQDAIKKGFAAQEKRNDQIWS
VPYLPIDPADLGRSYEAVIRVNSQSGKGGFAWVIEQDQGLKLPKRMQAHFSKHVQELADE
LGRELQAGDIWDVFQKAYRLSGEQRFQLIDWDEAKGPDNTRVFAGKIGVEGKEQSVSGKG
NGLISSVTATIAESFGVSLDVKDYAEHSMGKSTDARAAAYVECALPDGRTVWGVGIDEDV
ATASVRAVLSAANAA
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
atgaccatgctgaaagacccttcggtcaagtatcgccccttcccgcagatcgacctgccg
aaccgccagtggccctcgcaggtcatcaccaaggcgccccgctggctctccaccgacctg
cgtgacggcaaccaagcgctgatcgacccgatgggcgcggaaaagaagagccgcttcttc
gacctgctggtgaaagtcggcctcaaggaaatcgaggtcggcttcccgagcgcgggcgcg
accgagttcgacttcatccgcggcctcgtcgatcaggatcgcatccccgaggacgtgctg
gtgcaagtgctgacccagtctcgccaggacctgatcgagcgtacgttcgagagcctggct
ggcgtgcacgcgggcatcgtccacctctacaacgccgtctcgccgctgtggcgcaatgtc
gtgttcggcatggaacggcatgaaatccgcggcattgcggaaaccggcgcgaagatcatg
cgcgatcaggcggcgaagtacccgcagaccaagtggcacttcgaatactcaccggagacg
ttctctaccgccgaactcgatttctcgatcgagtgctgcgaggcggtgatggaaatcctg
cagcccacgcccgagaaccccatcatcctcaacctgcccgcgacggtcgaggcggcgacg
ccgaacatctatgcggatcagatcgagtacttctgccgcaacctgccgaaccgcgatgcg
gcggtgatctcgctgcacacgcacaacgatcgcggcaccggcgtcgcggcggcggaactg
ggcctgatggccggcgccgaccgcgtcgagggctgcctgttcggcaacggcgagcgcacc
ggcaactgctgcctcgtgaccgtggcgatgaacatgtacacgcaaggggtgaacccggag
ctggacttctcggacatcgacgacgtcatccagacggtagaatactgcaaccagctcaag
gtggccgagcgtcatccctacggcggcgaactggtcttcactgcgttctccggctcgcac
caggacgcgatcaagaagggtttcgccgcgcaggagaagcgcaacgaccagatctggtcg
gtgccttatctcccgatcgaccccgccgatctgggtcgcagctacgaggcggtgatccgc
gtcaactcgcagtccggcaagggcggcttcgcctgggtgatcgagcaggaccagggcctc
aagctgcccaagcggatgcaggcgcacttctccaagcacgtacaagagctggctgacgaa
ctcggccgcgaactgcaggcgggcgacatctgggacgtgttccagaaggcctaccgcctg
agcggcgagcagcgcttccagctgatcgactgggatgaggccaaggggccggacaacacc
cgcgtcttcgcgggcaagatcggcgtcgagggcaaggagcagtcggtgtccggcaagggc
aacggcctgatttcctcggtcacggcgaccatcgccgagagcttcggcgtcagcctcgac
gtcaaggactatgccgagcactcgatgggcaagagcacggacgcccgcgccgcagcctac
gtcgaatgcgccctgcccgacggtcgcaccgtatggggcgtgggcatcgacgaggacgtc
gccaccgccagcgtgcgcgccgttctgagcgccgccaacgcggcctga
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