Nostoc sphaeroides: GXM_05744
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Entry
GXM_05744 CDS
T06325
Name
(GenBank) leuA, 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
nsh
Nostoc sphaeroides
Pathway
nsh00290
Valine, leucine and isoleucine biosynthesis
nsh00620
Pyruvate metabolism
nsh01100
Metabolic pathways
nsh01110
Biosynthesis of secondary metabolites
nsh01210
2-Oxocarboxylic acid metabolism
nsh01230
Biosynthesis of amino acids
Module
nsh_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
nsh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
GXM_05744
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
GXM_05744
Enzymes [BR:
nsh01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
GXM_05744
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
QFS48252
UniProt:
A0A5P8W6P5
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All DBs
Position
Gxm1:complement(5239685..5241391)
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AA seq
568 aa
AA seq
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MTTNSSPQLWLYDTTLRDGTQREGLSVSIEDKLRIARRLDQLGIPFIEGGWPGANPKDVQ
FFWQLQEDPLKQAEIVAFCSTRRPNSTAATEPMLQDILAAGTRWVTIFGKSWDLHVTTSL
KTTLEENLAMIRDTIEYLRSQGRRIIYDAEHWFDGYKHNPDYALQTLEAAIASGAEWLVL
CDTNGGTLPHEISQIVQDVVRATGELGTGELGTGDWGLGTSKDSSQSPIPNPQSPIPQIG
IHTHNDSEMAVANAIAAVMAGAKMVQGTINGYGERCGNANLCSLIPNLQLKLGYSCITED
QLTQLTEASRFVSEVVNLAPDEHAPFVGLSAFAHKGGIHVSAVERNPLTYEHIQPEQVGN
HRRIVISEQSGLSNVLAKARSFGIDLDHQKAEAKQILQRLKDLESEGFQFEAAEASFALL
MHEALGGRQKFFEVKGFQVHCDLIEGKETSNALATVKLAVDGKNILEAAEGNGPVAALDA
ALRKALVNFYPQIATFDLTDYKVRILNGHTGTAAKTRVLVESGNGRQRWTTVGVSTNILE
ASYQAVVEGLEYGLLLHSQAEAAVKASS
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
atgaccacaaattcttcacctcaactttggctctatgacactacattacgagatggcact
cagcgcgaggggctatcagtttcgatagaagataagttacgcattgctcgtagactcgat
caactgggaattccctttattgaaggcggttggcctggtgctaatcccaaggatgtacaa
tttttctggcaactccaagaagatccgctaaaacaagctgaaattgtggctttttgttcg
actcgccgccccaattctactgccgcaaccgaaccgatgctacaggatattttggctgcg
ggaactcgctgggtaacgatttttggcaagtcttgggatttacatgtcacaaccagcctc
aagacgacattagaagaaaatttggcgatgattcgtgacacgattgagtatctccgttct
caagggcgtcgcattatctacgatgccgaacattggtttgatggttacaagcacaatcca
gattatgctttacagacattagaggctgcgatcgcatctggtgctgaatggctagtcctt
tgtgatactaatggtggcactttaccccatgaaattagccaaattgttcaagatgtggta
agggcaactggggaactggggactggggaactggggactggggactggggactagggact
agtaaagactcttcccaatccccaatccctaatccccaatccccaatcccccaaattgga
attcatactcataacgattcggaaatggcggttgctaacgcaatagccgccgtgatggca
ggggcgaagatggtacaggggacaattaatggttacggtgaacgttgcgggaatgctaac
ctctgttcgttaattcccaatttacaattgaagctgggttacagttgtatcacagaagac
cagctaacacaacttacagaagctagtcgttttgttagtgaggtggtcaacctcgcgcca
gatgaacacgctccctttgtgggactttcggcttttgcccacaagggcggtattcatgta
tcagccgtggaacgtaatcccctgacttacgaacacattcagccggaacaagtggggaat
catcgccgcattgtgatttctgaacagtctggacttagcaatgttttagccaaagcccgc
agttttggaattgacctcgatcaccaaaaggcagaagccaagcaaattctccagcgcctc
aaagatttggagagtgaaggatttcaatttgaagcagcagaggccagttttgcgctactg
atgcacgaagctttgggaggtcgccagaagttttttgaagtcaaaggttttcaagtccac
tgtgacttgattgaggggaaagaaactagcaatgccctagctacggttaaactcgctgtt
gacggcaaaaatattctggaggcggcggaaggtaacggccccgtggctgcgttggatgcg
gctttacgcaaggctttggtgaatttttatccccaaatagcaacctttgatttgacagat
tacaaagtgcggattctcaatggacatacgggtactgcggcgaaaacccgtgtcttggta
gagtcgggcaatggtcgtcaacgctggacgacggtaggagtttctactaatattttggag
gcttcctatcaagctgtggtggaaggcttggaatatggtttgttattgcactctcaagcg
gaagcggcggtgaaagcctctagttga
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