Nocardia seriolae: NS506_02145
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Entry
NS506_02145 CDS
T04599
Symbol
hemD
Name
(GenBank) Uroporphyrinogen-III synthase
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
nsr
Nocardia seriolae
Pathway
nsr00860
Porphyrin metabolism
nsr01100
Metabolic pathways
nsr01110
Biosynthesis of secondary metabolites
nsr01120
Microbial metabolism in diverse environments
nsr01240
Biosynthesis of cofactors
Module
nsr_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
nsr_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
nsr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
NS506_02145 (hemD)
Enzymes [BR:
nsr01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
NS506_02145 (hemD)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
Motif
Other DBs
NCBI-ProteinID:
APA96212
UniProt:
A0ABC8AQ20
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All DBs
Position
2276679..2278262
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AA seq
527 aa
AA seq
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MTEVDGGTPLAGFTVGITAARRADELGTLLARRGANIVSAPAIRIIPLADDTELERVTRR
LVDDPPQITVATTGIGFRGWMEAAEGWGLAEELRDTLGSTRMLARGPKAKGAIRAAELRE
EWSPASESSAEVLDHLLAEGVEGVRIAVQLHGATTEWEPVPDFCEVLRMAGADVVPVPVY
RWVPPDDRTPMDRLIEGIVTAGLDCVTFTSAPAVASLLMRAKETGLLEAVLHAFRTRVLP
ACVGPITAAPLEELGVTTSMPGRARLGALARHVAEELPRRANRIQAAGHNLSVRGGCVVV
DGQVRQLAPAPMALMRSLARQPGRVVSREDLLAALPGGGDDTHAVETAIARLRAGLGTPK
AIQTVVKRGYRLALDPAERIDNPHPEPAGPAGRQPSPAHSAGLGARREMPSRGFGGRPVP
EVPPAGAAPRRPGSPSAVNGAARPAMAPTVAGNGVARPVSAAEAQPNGAVRQPGGAVRQP
GGAVRQPDSAVRQPGGMVRQPKGAVRQSFPARSFGPAGSAGPARGVW
NT seq
1584 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaggtcgacggcggtaccccgctcgctggattcacggtcggcatcacggccgcc
cgacgcgccgacgaactcggcaccctgctcgcccgccggggcgcgaacatcgtttcagcc
ccggccatccggatcattccgctcgccgacgacaccgagctggagcgcgtgacgcgccgg
ctggtcgacgacccgccgcagatcacggtggccaccaccggcatcggcttccgcggctgg
atggaggccgcggagggctggggcctggccgaggagctgcgcgacaccctgggctcgacc
cgcatgctggcccgcggccccaaggccaagggcgcgatccgcgccgcggaactgcgcgag
gaatggtctcccgcttccgaatccagcgccgaggtgctggatcacctgctggccgagggc
gtcgagggcgtccgcatcgcggtgcagctgcacggcgcgaccaccgagtgggagccggtt
cccgacttctgcgaggtgctgcgcatggccggggccgacgtggtcccggttccggtctac
cggtgggtcccgccggacgaccgcacccccatggaccgcctcatcgagggcatcgtcacc
gccggactggactgcgtgaccttcaccagcgcccccgccgtggcgtcactgctcatgcgt
gccaaggagaccgggctgctggaggccgtcctgcacgccttccgcacccgggtgctgccc
gcctgcgtcgggcccatcacggccgccccgctcgaggagctgggcgtgaccacctccatg
cccggccgcgcccggctgggcgcgctggcccggcacgtcgccgaggaactgccccggcgc
gccaatcggattcaggccgcgggccacaatctgagcgtgcgcggcggctgcgtggtcgtc
gacggccaggtgcgtcagctggcgcccgcgccgatggcgctcatgcgttcgctggcccgc
cagcccggtcgcgtggtctcgcgcgaggatctgctcgccgccctgcccggcggcggtgac
gacacccacgccgtggagaccgccatcgcccgcctgcgcgcgggcctgggcacccccaag
gcgattcagaccgtggtcaagcgcggttaccggctggcgctggacccggccgaacgcatc
gacaatccgcacccggaaccggcgggtccggccggccgccagccgtccccggcgcactcg
gcgggcctgggcgcacgccgcgagatgccgtcgcgcggcttcggcggacgcccggtgccc
gaggtgcccccggccggtgcggcgccgcgccggcccggctcgcccagcgcggtcaacggt
gccgcgcgtcccgcgatggccccgacggtcgccggaaacggtgtcgcccggccggtctcg
gccgccgaggcgcagcccaacggcgcggtgcgacagcccggcggcgcagtacggcagccg
ggcggcgcggtgcgacagcccgatagtgcggtgcggcagcccggcggcatggtgcgccag
cccaagggtgctgtacggcagtcttttccggcacggtcgttcggtccggcgggttccgcg
ggcccggcccggggcgtctggtga
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