Neomonachus schauinslandi (Hawaiian monk seal): 110569843
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Entry
110569843 CDS
T08474
Symbol
PCK1
Name
(RefSeq) phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X1
KO
K01596
phosphoenolpyruvate carboxykinase (GTP) [EC:
4.1.1.32
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00010
Glycolysis / Gluconeogenesis
nsu00020
Citrate cycle (TCA cycle)
nsu00620
Pyruvate metabolism
nsu01100
Metabolic pathways
nsu03320
PPAR signaling pathway
nsu04068
FoxO signaling pathway
nsu04151
PI3K-Akt signaling pathway
nsu04152
AMPK signaling pathway
nsu04910
Insulin signaling pathway
nsu04920
Adipocytokine signaling pathway
nsu04922
Glucagon signaling pathway
nsu04931
Insulin resistance
nsu04964
Proximal tubule bicarbonate reclamation
Module
nsu_M00003
Gluconeogenesis, oxaloacetate => fructose-6P
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
110569843 (PCK1)
00020 Citrate cycle (TCA cycle)
110569843 (PCK1)
00620 Pyruvate metabolism
110569843 (PCK1)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
110569843 (PCK1)
04151 PI3K-Akt signaling pathway
110569843 (PCK1)
04152 AMPK signaling pathway
110569843 (PCK1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
110569843 (PCK1)
04922 Glucagon signaling pathway
110569843 (PCK1)
04920 Adipocytokine signaling pathway
110569843 (PCK1)
03320 PPAR signaling pathway
110569843 (PCK1)
09155 Excretory system
04964 Proximal tubule bicarbonate reclamation
110569843 (PCK1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04931 Insulin resistance
110569843 (PCK1)
Enzymes [BR:
nsu01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.32 phosphoenolpyruvate carboxykinase (GTP)
110569843 (PCK1)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PEPCK_GTP
PEPCK_N
Motif
Other DBs
NCBI-GeneID:
110569843
NCBI-ProteinID:
XP_021533476
UniProt:
A0A2Y9G366
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Position
10:132993599..132998876
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AA seq
622 aa
AA seq
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MPPQLQNGLNFSAKVIQGTLDSLPQAVRAFLESSVRLCQPEHIHICDGSEGENQQLLDQM
EGEGMIKRLQKLNNCWLALTDPRDVARIESKTVIITQEQRDTMPIPKTGLSQLGRWMSEE
DFEKAFKARFPGCMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVTSMRIMTRMGTAV
LEALGDAEFVKCLHSVGCPLPLKRPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSL
LGKKCFALRMASRLAKEEGWLAEHMLILGITNPKGQKKYFAAAFPSACGKTNLAMMNPSL
PGWKIECVGDDIAWMKFDQQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNV
AETSDGGIYWEGIDQPLAPGIRITSWKNKEWTPQDGEPCAHPNSRFCTPASQCPIIDPAW
ESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHQGKVIMHDPF
AMRPFFGYNFGKYLAHWLSMAQRPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWM
FNRISGEASAKLTPIGYVPEEGALNLTGLGDINTKELFHLSKEFWEKEVEDIQKYLEEQV
NTDLPCEIEREVLALKQRISQM
NT seq
1869 nt
NT seq
+upstream
nt +downstream
nt
atgcctcctcagctccaaaacggcctcaacttctcagccaaagtcatccagggcacccta
gacagcctgccccaggcagtgagagcattcctggagagcagcgtcaggctgtgccagcct
gagcatatccacatctgtgatggctccgagggggagaaccagcagctgctggaccaaatg
gaaggagagggcatgatcaagaggctgcagaagctcaacaactgctggttggctctcact
gaccccagggatgtggccagaattgaaagcaagacagtcatcattacccaagagcaaaga
gataccatgcccatccccaaaactggcctcagccaactaggtcgctggatgtcagaggag
gactttgagaaagcgttcaaagcccgatttccagggtgcatgaaaggtcgcaccatgtac
gtgatcccattcagcatggggcccctgggctcaccactgtcgaagatcggcatcgagctg
acggattcaccctacgtggtgaccagcatgcgcatcatgacacggatgggcacagccgtc
ctggaagctctgggggatgcggaattcgtcaagtgcctccattctgtgggatgcccttta
cctttaaaaaggcctttggtgaacaactggccgtgtaacccagagctgacactcatcgcg
cacctgcctgaccgcagggaaatcatctcctttgggagtgggtacggcgggaactcgctc
cttgggaagaagtgctttgccctcaggatggccagccggctggctaaggaagagggttgg
ctggcggaacacatgctgatcctgggcataaccaaccccaagggccagaagaagtacttc
gcagcagcctttcccagtgcctgtggcaagaccaacctggccatgatgaaccccagcctc
cctgggtggaaaatagaatgtgtgggtgatgacatcgcctggatgaaatttgaccaacaa
ggtaacttaagggctatcaacccagaaaatggcttttttggtgtggctcccggaacctct
gtgaagaccaaccccaatgccatcaagaccatccagaagaacaccatcttcaccaatgtg
gccgagaccagtgatgggggcatttactgggaaggtatcgaccagccgctagccccgggc
atcaggatcacttcgtggaagaacaaggagtggaccccccaggatggggaaccttgtgcc
catcccaactcacgcttctgcacccctgccagccagtgccccatcattgaccctgcctgg
gaatctccggaaggggtgcccattgagggcatcatctttgggggccgccgacctgctggt
gtccccctggtctatgaagctctcagttggcaacacggagtttttgtgggggcggccatg
cgatcagaggccacagcggctgcagaacaccaaggcaaggtcatcatgcacgaccccttt
gccatgcggcccttctttggctacaactttggcaaatacctggctcactggctcagcatg
gcccagcgcccagcagccaagctgcccaagatcttccatgtcaactggttccggaaagac
aaggaaggcaaattcctctggccaggctttggtgagaactccagggtgctggagtggatg
ttcaaccgcatcagtggggaagccagcgccaagctcacgcccatcggctacgtccccgag
gagggggccctgaacctgacaggcctgggggacatcaacacgaaggagctcttccacctg
tccaaggagttctgggagaaggaggtggaagacatccagaagtacctagaggagcaggtt
aacaccgatctcccctgtgaaatcgagagagaggtccttgccctgaagcaaaggatcagc
cagatgtaa
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