KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110570428
Entry
110570428         CDS       T08474                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04010  MAPK signaling pathway
nsu04015  Rap1 signaling pathway
nsu04218  Cellular senescence
nsu04380  Osteoclast differentiation
nsu04620  Toll-like receptor signaling pathway
nsu04664  Fc epsilon RI signaling pathway
nsu04668  TNF signaling pathway
nsu04750  Inflammatory mediator regulation of TRP channels
nsu04912  GnRH signaling pathway
nsu04935  Growth hormone synthesis, secretion and action
nsu04936  Alcoholic liver disease
nsu05014  Amyotrophic lateral sclerosis
nsu05022  Pathways of neurodegeneration - multiple diseases
nsu05132  Salmonella infection
nsu05135  Yersinia infection
nsu05145  Toxoplasmosis
nsu05161  Hepatitis B
nsu05163  Human cytomegalovirus infection
nsu05167  Kaposi sarcoma-associated herpesvirus infection
nsu05169  Epstein-Barr virus infection
nsu05170  Human immunodeficiency virus 1 infection
nsu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
nsu05417  Lipid and atherosclerosis
nsu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110570428 (MAP2K6)
   04015 Rap1 signaling pathway
    110570428 (MAP2K6)
   04668 TNF signaling pathway
    110570428 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    110570428 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    110570428 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    110570428 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    110570428 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    110570428 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    110570428 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    110570428 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    110570428 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    110570428 (MAP2K6)
   05161 Hepatitis B
    110570428 (MAP2K6)
   05163 Human cytomegalovirus infection
    110570428 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110570428 (MAP2K6)
   05169 Epstein-Barr virus infection
    110570428 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    110570428 (MAP2K6)
   05135 Yersinia infection
    110570428 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    110570428 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    110570428 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    110570428 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110570428 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    110570428 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    110570428 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nsu01001]
    110570428 (MAP2K6)
Enzymes [BR:nsu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     110570428 (MAP2K6)
Protein kinases [BR:nsu01001]
 Serine/threonine kinases: STE group
  STE7 family
   110570428 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase CLP1_P Haspin_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 110570428
NCBI-ProteinID: XP_021534123
UniProt: A0A2Y9G5I1
LinkDB
Position
15:49150563..49258423
AA seq 334 aa
MSQSKGRKRNPGLKIPKEAFEQPQPSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaggaagcgaaaccctggccttaaaattccaaaagaagcattt
gaacaacctcagcccagttccacgccacctcgagacttagactctaaagcttgcatttct
attggaaatcagaactttgaggtgaaggcggatgacctggaacctataatggaactgggg
cgaggtgcgtacggggtggtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaaaggctactgatggatttg
gatgtttccatgaggacagtggactgtccttttaccgtcaccttttatggtgcactcttc
cgggagggcgatgtttggatctgcatggagctcatggatacgtcgctagataaattctac
aaacaagtgatcgataaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcgttagaacacttacacagtaagctctctgtcattcatcgagacgtc
aagccttccaacgtgctgatcaacactctgggccaagtaaagatgtgcgattttggaatc
agtggctaccttgtagactctgttgctaaaactattgatgcaggatgcaaaccgtacatg
gcccctgaaagaataaacccagagctcaatcagaagggatacagtgtgaagtctgacatt
tggagtctgggcatcacaatgattgagttggcgatccttcggtttccctacgactcttgg
ggaacccccttccagcagctcaaacaggtggtcgaggaaccctcgccacaactcccggcg
gataaattctctgaagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaacggccaacatatccagaacttatgcaacatccatttttcaccctacacgaatccaaa
gcaacagacgtggcatcttttgtaaaactgattcttggagactaa

DBGET integrated database retrieval system