Neomonachus schauinslandi (Hawaiian monk seal): 110570861
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Entry
110570861 CDS
T08474
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X2
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
110570861 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
nsu03032
]
110570861 (TOP2B)
03036 Chromosome and associated proteins [BR:
nsu03036
]
110570861 (TOP2B)
Enzymes [BR:
nsu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
110570861 (TOP2B)
DNA replication proteins [BR:
nsu03032
]
Eukaryotic type
DNA Topoisomerases
110570861 (TOP2B)
Chromosome and associated proteins [BR:
nsu03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
110570861 (TOP2B)
Centrosome formation proteins
Centriole proteins
110570861 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
110570861
NCBI-ProteinID:
XP_021534597
UniProt:
A0A2Y9G6E8
LinkDB
All DBs
Position
1:complement(138039388..138100206)
Genome browser
AA seq
1618 aa
AA seq
DB search
MAKAGGGGGGGAGAGGNGALTWVNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHIL
LRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTC
IKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNG
YGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLS
KFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGV
ALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK
NKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASN
CGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDS
AKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDD
AESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNK
QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPE
DDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELI
LFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQAL
MMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLSRLLFPAVDDN
LLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLD
PHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPML
NGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFD
HMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKIT
IENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPDFNY
ILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFADELDKVEAQERE
DVLAGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADVSKKLLKKKKGDL
DTTTVKVEFDEEFSGTPVEGTGEEALVPSAPVNKGPKPKREKKEPGTRVRKTPTSSGKSS
AKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDD
DDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSSHDKKSQDFGN
LFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTTAK
PKRAPKQKKVEPINSDSDSEFGIPKKTTPPKGKGRGAKKRKASGSENEGDYNPGRKTSKT
TSKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4857 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcggcggcggcggcgcaggagccggcggcaacggggcactg
acctgggtgaacaatgctgcaaaaaaagaagagtcagaaactgcaaacaaaaatgattct
tcaaagaagttgtctgttgagagagtgtatcagaaaaagacacaacttgaacatattctc
cttcgtcctgatacatatattgggtcagtggaaccattgacacagctaatgtgggtgtat
gatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggtttatacaagatc
tttgatgaaattttggttaatgcagctgacaataaacagagggataagaatatgacctgt
attaaagtttctattgatcctgaatcaaatattataagcatttggaataatgggaaaggc
attccagtagtagaacacaaagtagagaaagtttatgttccagcgttaatttttggacag
cttttaacatccagtaactatgatgatgatgagaaaaaagtaacaggtggtcgcaatggt
tatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaactgcttgcaaa
gaatacaaacatagttttaagcagacatggatgaataacatgatgaagacttctgaagcc
aaaattaagcattttgatggtgaagattacacatgcataacattccaaccagatctgtct
aaatttaagatggaaaagcttgacaaggatattgtggccctcatgaccagaagagcttat
gatttggctggttcatgcaagggggtcaaggtcatgtttaatggaaagaaattgcctgta
aatggatttcgcagttatgtagatctttatgtgaaagacaagttggatgaaactggagtg
gcgctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctcacactgagt
gaaaagggattccagcaaatcagctttgtaaatagtattgcaacaacaaaaggtggacgt
catgtggattatgtagtagatcaagttgttggtaagctgattgaagtagttaagaaaaag
aacaaagctggtgtatcagtaaaaccatttcaagtaaaaaaccatatatgggtttttatt
aattgccttattgaaaatccaacttttgattctcagactaaggaaaacatgactctgcaa
cccaaaagttttgggtccaaatgccaactgtcagaaaaattttttaaagcagcttctaac
tgtggcattgtagaaagtattctgaattgggtgaaatttaaagcccagactcagctgaac
aagaagtgttcatcagtaaagtatagtaaaatcaaaggtattcccaaactggatgatgct
aatgatgctggtggcaaacattccctggagtgtacactgatattaacagagggagactct
gccaaatcgttggctgtgtctggattaggtgtgattgggcgagacagatatggagtcttt
ccacttaggggaaaaattcttaacgtacgggaagcttctcataaacagatcatggaaaat
gcagaaataaacaatattatcaaaatagttggtctacagtacaagaaaagttatgatgat
gcagaatctctgaaaactttacgctatgggaagattatgattatgactgatcaggatcaa
gatggttctcacattaaaggcctgcttattaatttcatccatcacaattggccatcactt
ttgaagcatggctttcttgaagagttcattactcctattgtgaaggctagcaaaaataag
caggaactttccttctatagtattcctgaatttgatgagtggaaaaaacatatagaaaac
cagaaagcctggaaaataaaatactacaaagggctgggtaccagcacagctaaagaagca
aaggaatattttgctgatatggaaaggcaccgcatcttgtttagatatgctggtcctgaa
gacgatgctgccattaccttggcattcagtaaaaagaagattgatgacagaaaagaatgg
ttaaccaattttatggaagaccggagacagcgtaggttacatggcttaccagagcaattt
ttgtatggtacagcaacaaagcatttgacttacaatgatttcatcaacaaggaattgatt
ctcttctcaaactcagacaatgaaagatctataccatctcttgttgatggttttaaacca
ggacaacgaaaagttttatttacctgtttcaagaggaatgataaacgtgaagtaaaagtt
gcccagttggctggatctgttgctgagatgtctgcttatcatcatggagaacaagcattg
atgatgactattgtgaatttggctcagaactttgtgggaagcaacaacattaacttgctt
cagcctattggtcagtttggaactcggcttcatggtggcaaagatgctgcaagccctcgt
tatattttcacaatgttaagctctttatcaagactgctttttcctgctgtggatgacaac
ctgctcaaattcctttatgatgataatcaacgcgttgagcctgagtggtatattcctata
attcccatggttttaataaatggtgctgagggcattggtactggatgggcttgtaaacta
cccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctagatggcttggat
cctcatcctatgcttccaaattacaaaaactttaaaggaaccatccaagagcttggtcaa
aaccagtatgcagtcagtggtgaaatatttgtggtggatagaaacacagtagagattaca
gagcttccagttagaacttggacacaggtatacaaagaacaggttttagaacctatgtta
aatggaacagataaaacaccggcattaatttctgattataaagaatatcatactgataca
actgtgaaatttgtggtgaaaatgactgaagagaagctagcacaagcagaagctgctgga
ttgcacaaagtttttaaacttcaaactactcttacgtgtaattccatggtactctttgat
catatgggatgtctcaagaagtatgaaaccgtgcaagacattttgaaagaattctttgat
ttacgattaagttattatggtttacgtaaggagtggcttgtaggaatgttgggagcagag
tctacaaagcttaacaatcaagcccgtttcattttagagaagatacaaggaaaaattact
atagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttatgaatct
gacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaagaaacacaa
aaccagcatgatgatagttcctctgattcaggaactccttcaggccccgattttaattat
attttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactgattaaacag
agagatgctaaagggcgagaagtcaatgatcttaaaagaaaatcgccttcagatctttgg
aaagaagacttagcagcatttgctgatgaactggataaagtggaagcgcaagaacgagag
gatgttctggccggaatggctggaaaagcaataaaaggtaaagttggcaaacctaaggtg
aagaaacttcaattggaagagacaatgccctcaccttatgggagaagaatagttcctgaa
attactgctatgaaggcagatgtcagcaaaaagttgctgaagaagaaaaagggtgatctt
gataccacaacagtaaaagtagaatttgatgaagaattcagtggaacaccagtagagggt
actggagaagaggcattggtcccgtcagctcctgtaaataaaggtcccaaacccaaaagg
gagaaaaaggagcctggtaccagggtgagaaaaacacctacatcatctggtaaatccagt
gcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaagtcagaaagtgac
ttggaagaaacagaacctgtggttattccaagagattctttgcttaggagagcagctgct
gaaaggcctaagtacacatttgatttctcagaagaagaggatgatgatgctgatgatgat
gacgacaataatgatttagaggagctgaaagttaaagcatctcccataacaaatgatggg
gaagatgaatttgttccttcagatggcctagataaagatgaatatacattttcaccaggc
aaatcaaaagctactccagaaaaatcttcacatgacaaaaaaagtcaagattttgggaat
ctcttctcatttccttcatactctcagaagtcagaagatgattcagctaaatttgacagt
aatgaagaagattctgcctctgttttttcaccatcatttggtctgaaacaaacagataag
gttccaagtaaaacagtagctgctaaaaagggaaaaccgtcttcagatacaactgctaag
cccaagagagctcctaaacagaagaaagtagagcctatcaactctgactcagattcagaa
tttggcattccaaagaagactacacccccaaaaggtaaaggccgaggggcaaagaaaagg
aaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaaacatccaaaaca
acaagcaagaaaccgaagaaaacatcttttgatcaggattcagatgtggacatcttccca
tcagacttcacttctgaaccaccttctctgccacggaccggtagggctaggaaagaagta
aaatattttgcagagtctgatgaagaagaagatgttgattttgcaatgtttaattaa
DBGET
integrated database retrieval system
