KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110572137
Entry
110572137         CDS       T08474                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04010  MAPK signaling pathway
nsu04020  Calcium signaling pathway
nsu04022  cGMP-PKG signaling pathway
nsu04114  Oocyte meiosis
nsu04218  Cellular senescence
nsu04310  Wnt signaling pathway
nsu04360  Axon guidance
nsu04370  VEGF signaling pathway
nsu04380  Osteoclast differentiation
nsu04625  C-type lectin receptor signaling pathway
nsu04650  Natural killer cell mediated cytotoxicity
nsu04658  Th1 and Th2 cell differentiation
nsu04659  Th17 cell differentiation
nsu04660  T cell receptor signaling pathway
nsu04662  B cell receptor signaling pathway
nsu04720  Long-term potentiation
nsu04724  Glutamatergic synapse
nsu04728  Dopaminergic synapse
nsu04921  Oxytocin signaling pathway
nsu04922  Glucagon signaling pathway
nsu04924  Renin secretion
nsu05010  Alzheimer disease
nsu05014  Amyotrophic lateral sclerosis
nsu05020  Prion disease
nsu05022  Pathways of neurodegeneration - multiple diseases
nsu05031  Amphetamine addiction
nsu05152  Tuberculosis
nsu05163  Human cytomegalovirus infection
nsu05166  Human T-cell leukemia virus 1 infection
nsu05167  Kaposi sarcoma-associated herpesvirus infection
nsu05170  Human immunodeficiency virus 1 infection
nsu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
nsu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110572137 (PPP3CA)
   04310 Wnt signaling pathway
    110572137 (PPP3CA)
   04370 VEGF signaling pathway
    110572137 (PPP3CA)
   04020 Calcium signaling pathway
    110572137 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    110572137 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    110572137 (PPP3CA)
   04218 Cellular senescence
    110572137 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    110572137 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    110572137 (PPP3CA)
   04660 T cell receptor signaling pathway
    110572137 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    110572137 (PPP3CA)
   04659 Th17 cell differentiation
    110572137 (PPP3CA)
   04662 B cell receptor signaling pathway
    110572137 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    110572137 (PPP3CA)
   04921 Oxytocin signaling pathway
    110572137 (PPP3CA)
   04924 Renin secretion
    110572137 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    110572137 (PPP3CA)
   04728 Dopaminergic synapse
    110572137 (PPP3CA)
   04720 Long-term potentiation
    110572137 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    110572137 (PPP3CA)
   04380 Osteoclast differentiation
    110572137 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    110572137 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    110572137 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    110572137 (PPP3CA)
   05163 Human cytomegalovirus infection
    110572137 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110572137 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    110572137 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    110572137 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    110572137 (PPP3CA)
   05020 Prion disease
    110572137 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    110572137 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    110572137 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110572137 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:nsu01009]
    110572137 (PPP3CA)
Enzymes [BR:nsu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     110572137 (PPP3CA)
Protein phosphatases and associated proteins [BR:nsu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     110572137 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 110572137
NCBI-ProteinID: XP_044768839
UniProt: A0A8M1MCR3
LinkDB
Position
2:120624352..120939349
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagccaaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gtcccatttcctccaagtcaccggcttacagcaaaagaagtgtttgataatgatgggaaa
cctcgtgtggatatcttaaaggcacatctcatgaaggagggcaggctggaagagagcgtt
gcattgagaataataacagagggggcttcaattcttcgacaggaaaaaaatttgctggat
attgatgcaccagtcacagtttgtggggacatccatggacaattctttgacttgatgaag
ctctttgaagtggggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggccttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtctatgatgcctgtatggat
gcctttgactgcctgcccctggctgccctgatgaaccaacagttcctgtgtgtccacggc
ggtttgtctccagagattaatactttagacgatatcaggaaattagaccgattcaaagaa
ccacctgcttatggacctatgtgtgatatcctgtggtcagaccccctggaggattttgga
aacgagaagactcaggaacatttcactcacaacacagtcagggggtgttcatacttctac
agttacccagctgtatgtgaattcttgcagcacaataatttgttatctatactccgagcc
catgaagcccaagatgcagggtatcgcatgtacaggaagagccaaacgacaggcttccct
tctctaattacaattttctcagcaccaaattatttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgtcatgaatatcaggcaattcaactgttctcctcaccca
tactggcttccaaatttcatggatgttttcacttggtccctgccattcgttggagaaaaa
gtgactgagatgctggtaaatgtcctcaacatctgctcagatgatgaactagggtcagaa
gaagatgggtttgacggagcgacagctgcagcccggaaggaggtgataaggaacaagatc
cgagcaataggcaaaatggcccgagtgttctcggttctcagagaagagagcgagagtgtg
ctgacgctgaaaggcttgacccccacgggtatgctccccagcggagtgctttctggaggg
aagcagacactgcaaagcgctactgttgaggctattgaggctgatgaagcaatcaaagga
ttttcaccacaacataagatcactagcttcgaggaggccaagggcttagaccgaattaac
gagaggatgccacctcgcagagatgccatgccctctgacgccaaccttaactccatcaac
aaggctctcgcctcagagactaacggcacggacagcaatggcagtaatagcagcaatatc
cagtga

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