Neomonachus schauinslandi (Hawaiian monk seal): 110572370
Help
Entry
110572370 CDS
T08474
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu01521
EGFR tyrosine kinase inhibitor resistance
nsu01522
Endocrine resistance
nsu04010
MAPK signaling pathway
nsu04014
Ras signaling pathway
nsu04015
Rap1 signaling pathway
nsu04066
HIF-1 signaling pathway
nsu04068
FoxO signaling pathway
nsu04081
Hormone signaling
nsu04114
Oocyte meiosis
nsu04140
Autophagy - animal
nsu04144
Endocytosis
nsu04150
mTOR signaling pathway
nsu04151
PI3K-Akt signaling pathway
nsu04152
AMPK signaling pathway
nsu04211
Longevity regulating pathway
nsu04213
Longevity regulating pathway - multiple species
nsu04510
Focal adhesion
nsu04520
Adherens junction
nsu04550
Signaling pathways regulating pluripotency of stem cells
nsu04730
Long-term depression
nsu04913
Ovarian steroidogenesis
nsu04914
Progesterone-mediated oocyte maturation
nsu05200
Pathways in cancer
nsu05202
Transcriptional misregulation in cancer
nsu05205
Proteoglycans in cancer
nsu05214
Glioma
nsu05215
Prostate cancer
nsu05218
Melanoma
nsu05224
Breast cancer
nsu05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110572370 (IGF1R)
04014 Ras signaling pathway
110572370 (IGF1R)
04015 Rap1 signaling pathway
110572370 (IGF1R)
04066 HIF-1 signaling pathway
110572370 (IGF1R)
04068 FoxO signaling pathway
110572370 (IGF1R)
04151 PI3K-Akt signaling pathway
110572370 (IGF1R)
04152 AMPK signaling pathway
110572370 (IGF1R)
04150 mTOR signaling pathway
110572370 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
110572370 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
110572370 (IGF1R)
04140 Autophagy - animal
110572370 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
110572370 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
110572370 (IGF1R)
04520 Adherens junction
110572370 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
110572370 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
110572370 (IGF1R)
04914 Progesterone-mediated oocyte maturation
110572370 (IGF1R)
09156 Nervous system
04730 Long-term depression
110572370 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
110572370 (IGF1R)
04213 Longevity regulating pathway - multiple species
110572370 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110572370 (IGF1R)
05202 Transcriptional misregulation in cancer
110572370 (IGF1R)
05205 Proteoglycans in cancer
110572370 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
110572370 (IGF1R)
05214 Glioma
110572370 (IGF1R)
05218 Melanoma
110572370 (IGF1R)
05215 Prostate cancer
110572370 (IGF1R)
05224 Breast cancer
110572370 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110572370 (IGF1R)
01522 Endocrine resistance
110572370 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nsu01001
]
110572370 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
nsu04090
]
110572370 (IGF1R)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
110572370 (IGF1R)
Protein kinases [BR:
nsu01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
110572370 (IGF1R)
CD molecules [BR:
nsu04090
]
Proteins
110572370 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
110572370
NCBI-ProteinID:
XP_021536327
UniProt:
A0A2Y9GBI4
LinkDB
All DBs
Position
9:126303291..126603178
Genome browser
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVTQVTNTTMSSRSRNTTVADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
ESRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPIAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPAFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtgggccgggcatcgacatccgc
aacgactatcagcagctgaagcgtctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctcgagagcctcggggacctcttc
ccgaacctcacggtcatccgcggctggaagctcttctacaactacgccctggtcatcttt
gagatgaccaatctcaaggatattgggctttacaatctgaggaacattactcggggggcc
atcaggattgagaagaatgctgacctctgttacctctccacggtggactggtccctgatc
ctggatgccgtgtccaataactacatcgtgggcaacaaacccccaaaggaatgcggggac
ctgtgtccggggacaatggaggagaagcccttgtgcgagaagacaaccatcaacaatgag
tacaactatcgttgctggactacaaaccgttgccagaaaatgtgcccgagcgcgtgcggg
aagcgggcgtgcaccgagaacaacgagtgctgtcaccccgagtgtctgggcagctgcagt
gcgcccgacaacgacacggcctgcgtggcgtgcaggcattactactacgcgggcgtctgc
gtgcccacctgcccgcccaacacctaccgcttcgagggctggcgctgcgtggatcgcgac
ttctgcgccaacatccccagcgccgagagcagcgactccgaggggttcgtgatccacgac
ggcgagtgcatgcaagagtgcccctcggggttcatccggaacggcagtcagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgtgaggaagaaaagaaaacaaaaacc
attgattctgttacctctgctcaaatgctccaaggatgcaccatcttcaagggcaatttg
ctcattaatattcgccgaggcaataacatcgcctcagaactggagaacttcatggggctc
atcgaggtggtgacaggctacgtgaagatccgccattctcacgccttggtctccttgtcc
ttcctaaaaaaccttcgccagatcttaggagaggagcagctagaagggaactactccttc
tatgtcctggacaaccagaacttgcagcagctgtgggactgggaccaccgcaacctgacc
atcaaagctgggaaaatgtactttgctttcaatcccaaattgtgcgtctccgagatttac
cgcatggaggaagtgacagggactaaggggcgccagagcaaaggggacataaacaccagg
aacaacggagagcgagcttcctgtgaaagtgatgtcctgcatttcacctctacgaccacg
tggaagaatcgcatcatcataacatggcaccgttaccggccccccgactacagggacctc
atcagcttcactgtctactacaaggaagcaccttttaaaaacgtcacggagtatgatggg
caggatgcctgtggctccaacagctggaacatggtggatgtggacctccctcccaacaag
gacgtcgagcctggcattctactgcatggactgaagccctggacgcagtatgctgtgtat
gtcaaggcggtgaccctcaccatggtggagaacgaccacatccgtggggccaaaagtgaa
atcttgtacattcgcaccaatgcttcagttccttccattcccctggacgttctttccgcg
tccaactcctcctctcagctcatcgtgaagtggaacccgccctccctgcccaacggcaac
ctcagttactacatcgtgagatggcagcggcagcctcaggacagctacctttacaggcat
aactactgctccaaagacaaaatccccatcaggaagtatgccgacggcaccatcgacgtg
gaagaggtgacggagaatcccaagaccgaggtgtgcggcggagagaaggggccttgctgc
gcctgccccaaaaccgaggccgagaagcaggccgagaaggaggaggctgagtaccgcaaa
gtcttcgagaactttctgcacaactccatctttgtgcccagacctgaaaggaagcggaga
gacgtcacacaagtcaccaacaccaccatgtccagccgaagcaggaacaccacagtggca
gacacctataatatcacagacccagaagaactcgagacagaataccctttctttgagagc
agagtggataacaaggagagaactgtaatctctaacctccggccttttactttgtaccgc
attgacatccacagctgtaaccacgaggctgagaagctgggctgcagcgcctccaacttt
gtttttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccggtgacctgg
gagtcgaggcctgaaaactccatctttctaaagtggccggaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatatggatcacagatcgaggatcagcgggaatgtgta
tcgagacaggagtacaggaagtatggaggtgccaagcttaaccggctcaaccccgggaac
tatacggcccggatccaggccacctctctctctgggaatgggtcctggacggatcctgtg
ttcttctacgtcccagccaaaataacgtatgaaaacttcatccatctgatcatcgctctg
cccattgctgtcctgttgatagtgggagggctggttataatgctgtatgtcttccacagg
aaaagaaataacagcaggctggggaatggagtgctgtacgcttccgtgaacccagagtac
ttcagcgccgccgacgtgtatgtacctgacgagtgggaagttgctcgagagaagatcacc
atgagccgagagctggggcagggctcatttgggatggtatacgaaggagttgccaaaggc
gtggttaaagatgagccagaaaccagggtggccattaaaacagtgaatgaggccgcgagc
atgcgtgaaaggattgaatttctcaatgaggcttcagtgatgaaggagttcaattgtcac
cacgtggtgcggttgctgggcgtagtgtcccagggccagccgacgctggtcatcatggaa
ctgatgacacggggggatctcaaaagctatctcaggtctctgaggccagaaatagagaat
aatccagtcctagcacctccaagcctaagcaagatgatccagatggctggggagattgca
gatggcatggcatacctcaacgccaacaagtttgtccacagagaccttgctgcccggaac
tgcatggtggccgaagatttcacggtcaaaatcggagatttcggtatgacgagagacatc
tacgagacagactactaccggaaaggaggaaaggggttgctgcctgtgcgctggatgtcc
cccgagtctctcaaggatggagtcttcactactcactccgacgtctggtccttcggcgtc
gtgctctgggagatcgccacgctggccgagcagccctaccagggcttgtccaacgagcag
gtccttcgcttcgttatggagggcggccttctggacaagccggacaactgccccgacatg
ctgtttgagctgatgcgcatgtgctggcagtacaaccccaagatgaggcctgccttcctg
gagatcatcagcagcatcaaggacgagatggagcctggcttccgggaggtctccttctac
tacagcgaggagaacaagccgcccgagcccgaggagctggacctggagcccgaaaacatg
gagagcgtccccctggacccctccgcctcctcgtcctccctgccgctgcccgacagacac
tcaggacacaaggccgagaacggcccgggccctggcgtgctggttctccgagccagcttc
gatgagagacagccttacgcgcacatgaacgggggacgcaagaacgagagggccttgccc
ctgccccagtcttcgacctgctga
DBGET
integrated database retrieval system
