KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110572498
Entry
110572498         CDS       T08474                                 
Symbol
SOCS3
Name
(RefSeq) LOW QUALITY PROTEIN: suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04120  Ubiquitin mediated proteolysis
nsu04380  Osteoclast differentiation
nsu04630  JAK-STAT signaling pathway
nsu04668  TNF signaling pathway
nsu04910  Insulin signaling pathway
nsu04917  Prolactin signaling pathway
nsu04920  Adipocytokine signaling pathway
nsu04930  Type II diabetes mellitus
nsu04931  Insulin resistance
nsu04932  Non-alcoholic fatty liver disease
nsu04935  Growth hormone synthesis, secretion and action
nsu05160  Hepatitis C
nsu05164  Influenza A
nsu05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    110572498 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    110572498 (SOCS3)
   04668 TNF signaling pathway
    110572498 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    110572498 (SOCS3)
   04920 Adipocytokine signaling pathway
    110572498 (SOCS3)
   04917 Prolactin signaling pathway
    110572498 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    110572498 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    110572498 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    110572498 (SOCS3)
   05164 Influenza A
    110572498 (SOCS3)
   05168 Herpes simplex virus 1 infection
    110572498 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    110572498 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    110572498 (SOCS3)
   04931 Insulin resistance
    110572498 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:nsu04121]
    110572498 (SOCS3)
Ubiquitin system [BR:nsu04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     110572498 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 110572498
NCBI-ProteinID: XP_021536491
UniProt: A0A2Y9GBR7
LinkDB
Position
15:complement(56301865..56304229)
AA seq 225 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPPGAPSFPSPPTEPSSEVPEQPPSQPLPGNPPRRAYYIYSGGEKIPLVLSR
PLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 678 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttctactggagcgccgtgacgggcggcgaggcgaacctgctgctc
agcgccgagcccgccggcaccttcctcatccgcgacagctcggaccagcgccacttcttc
acgctcagcgtcaagacccagtcggggaccaagaatctgcgcatccagtgcgaggggggc
agcttctcgctgcagagcgacccccggagcacgcagccggtgccccgcttcgactgcgtg
ctcaagctggtgcatcactacatgccgccccccggcgccccctccttcccctctccgccg
accgaaccctcctcggaggtgccggagcagccgccatcccagccgctcccagggaatcct
cccaggagagcctattacatctactcggggggcgagaagatccctctagtgttgagccgg
cccctctcctccaacgtggccactctccaacatctctgtcggaagaccgtcaatggccac
ctggactcctatgagaaagtcacccagctgcctgggcccattcgggaattcctggaccag
tacgatgccccgctttaa

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