KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110573154
Entry
110573154         CDS       T08474                                 
Symbol
FGFR1
Name
(RefSeq) fibroblast growth factor receptor 1 isoform X2
  KO
K04362  fibroblast growth factor receptor 1 [EC:2.7.10.1]
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04010  MAPK signaling pathway
nsu04014  Ras signaling pathway
nsu04015  Rap1 signaling pathway
nsu04020  Calcium signaling pathway
nsu04151  PI3K-Akt signaling pathway
nsu04520  Adherens junction
nsu04550  Signaling pathways regulating pluripotency of stem cells
nsu04714  Thermogenesis
nsu04810  Regulation of actin cytoskeleton
nsu04928  Parathyroid hormone synthesis, secretion and action
nsu05200  Pathways in cancer
nsu05205  Proteoglycans in cancer
nsu05215  Prostate cancer
nsu05218  Melanoma
nsu05224  Breast cancer
nsu05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110573154 (FGFR1)
   04014 Ras signaling pathway
    110573154 (FGFR1)
   04015 Rap1 signaling pathway
    110573154 (FGFR1)
   04020 Calcium signaling pathway
    110573154 (FGFR1)
   04151 PI3K-Akt signaling pathway
    110573154 (FGFR1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    110573154 (FGFR1)
   04550 Signaling pathways regulating pluripotency of stem cells
    110573154 (FGFR1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    110573154 (FGFR1)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    110573154 (FGFR1)
  09159 Environmental adaptation
   04714 Thermogenesis
    110573154 (FGFR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110573154 (FGFR1)
   05205 Proteoglycans in cancer
    110573154 (FGFR1)
   05230 Central carbon metabolism in cancer
    110573154 (FGFR1)
  09162 Cancer: specific types
   05218 Melanoma
    110573154 (FGFR1)
   05215 Prostate cancer
    110573154 (FGFR1)
   05224 Breast cancer
    110573154 (FGFR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nsu01001]
    110573154 (FGFR1)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:nsu04090]
    110573154 (FGFR1)
   00536 Glycosaminoglycan binding proteins [BR:nsu00536]
    110573154 (FGFR1)
Enzymes [BR:nsu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     110573154 (FGFR1)
Protein kinases [BR:nsu01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   110573154 (FGFR1)
CD molecules [BR:nsu04090]
 Proteins
  110573154 (FGFR1)
Glycosaminoglycan binding proteins [BR:nsu00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   110573154 (FGFR1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set V-set_CD47 C2-set_2 ABC1 Pkinase_fungal DUF1615 zf-CCCH_9
Other DBs
NCBI-GeneID: 110573154
NCBI-ProteinID: XP_021537252
UniProt: A0A2Y9GE03
LinkDB
Position
2:complement(35196958..35244061)
AA seq 735 aa
MWSWKCLLFWAVLVTAALCTARPAPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM
PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKHSGINSSDAEVLTLFNV
TEAQSGEYVCKVSNYIGEANQSAWLTVTRPVAKALEERPAVMTSPLYLEIIIYCTGAFLI
SCMVGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPS
RLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNR
VTKVAVKMLKADATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKG
NLREYLQARRPPGLEYCYNPSHSPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAAR
NVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFG
VLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTF
KQLVEDLDRIVALTSNQEYLDLSVPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCL
PRHPAQLANGGLKRR
NT seq 2208 nt   +upstreamnt  +downstreamnt
atgtggagctggaagtgtctcctcttctgggctgtgctggtcacagccgcgctctgcact
gctaggccggccccgaccttgcctgaacaagatgctctcccctcctcggaggacgacgat
gatgatgatgactcctcttcagaggagaaagagacagataacaccaaaccaaaccgtatg
cccgtggctccatactggacatccccagaaaagatggaaaagaaattgcacgcagtgcca
gctgccaagactgtgaagttcaaatgcccttccagtgggactcccaaccccacactgcgc
tggctgaaaaatggcaaagaattcaaacctgaccacaggattggaggctacaaggtccgt
tacgccacctggagcatcataatggattccgtggtgccttcggataagggcaactacacc
tgcatcgtggagaacgaatatggcagcattaaccacacctaccagctcgacgtcgtggag
cggtcccctcaccggcccatcctgcaggcagggttgcctgccaacaagaccgtggccctg
ggcagcaatgtggagttcatgtgtaaggtgtacagtgacccacagccccatatccagtgg
ctaaagcacatcgaggtgaatggcagtaagattggtccagacaacctgccgtatgtccag
atcttgaagcattcggggattaatagctcggatgcggaggtgctgaccctgttcaatgtg
acagaggcccagagcggggagtatgtgtgtaaggtttccaattatattggtgaagctaac
cagtctgcgtggctcactgtcaccagacctgtggcaaaagccctggaagagaggccagca
gtgatgacctcgcccctgtacctggagatcatcatctattgcacgggggccttcctcatt
tcctgcatggtggggtctgtcatcatctacaagatgaagagtggtaccaagaagagcgac
ttccacagccagatggccgtgcacaagctagccaagagcatccctctgcgcagacaggta
acagtgtcggcggattccagtgcatccatgaactctggggttctgctcgttcggccctca
cgtctctcctctagtggaacccccatgctggccggggtctctgaatacgagcttcctgaa
gaccctcgctgggagctgcctcgagacaggctggttttaggcaaacccctgggagagggc
tgctttgggcaggtggtgttggcggaggccattgggctggacaaggacaaacccaaccgt
gtgaccaaagtggctgtgaagatgttgaaggcggacgcgacagagaaagacctgtcagac
ctgatctcagaaatggagatgatgaagatgatcgggaagcacaagaacatcatcaacctg
ctgggggcctgcacacaggacggtcctttgtacgtcatcgtggagtacgcctccaaaggc
aacctacgggagtacctgcaggcccggaggcctcctgggctggagtactgttacaacccc
agccacagcccagaggagcagctctcctccaaggacctggtgtcctgcgcctatcaggtg
gcccggggcatggagtatctcgcctccaagaagtgcatacaccgagacctggccgccagg
aacgtgctggtgaccgaggacaacgtgatgaagatcgcagacttcggcctcgcgcgggac
attcaccacatcgactactataaaaagacaaccaacggccggctgcctgtgaagtggatg
gcccccgaggccttgtttgaccggatctacacccaccagagcgacgtctggtcttttggg
gtgctcctgtgggaaatcttcaccctgggaggctccccatatcccggcgtgcctgtggag
gagcttttcaagctgctgaaggagggtcatcggatggacaagcccagtaactgcaccaat
gagctatacatgatgatgcgggattgctggcacgcagtaccctctcagagacctaccttc
aagcagctggtggaagacctggaccgcattgtggccttgacctccaaccaggagtacctg
gacctgtccgtgcccctggaccagtactctccgagttttcccgacacccgaagctcaacc
tgctcctcgggggaggattcggtcttctctcatgagccgttgcccgaggagccctgtctg
ccccgacacccagcccagcttgccaatggcggactcaaacgacgctga

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