Neomonachus schauinslandi (Hawaiian monk seal): 110573862
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Entry
110573862 CDS
T08474
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04010
MAPK signaling pathway
nsu04020
Calcium signaling pathway
nsu04022
cGMP-PKG signaling pathway
nsu04024
cAMP signaling pathway
nsu04260
Cardiac muscle contraction
nsu04261
Adrenergic signaling in cardiomyocytes
nsu04270
Vascular smooth muscle contraction
nsu04723
Retrograde endocannabinoid signaling
nsu04725
Cholinergic synapse
nsu04726
Serotonergic synapse
nsu04727
GABAergic synapse
nsu04911
Insulin secretion
nsu04912
GnRH signaling pathway
nsu04921
Oxytocin signaling pathway
nsu04924
Renin secretion
nsu04925
Aldosterone synthesis and secretion
nsu04927
Cortisol synthesis and secretion
nsu04929
GnRH secretion
nsu04934
Cushing syndrome
nsu04935
Growth hormone synthesis, secretion and action
nsu05010
Alzheimer disease
nsu05020
Prion disease
nsu05022
Pathways of neurodegeneration - multiple diseases
nsu05207
Chemical carcinogenesis - receptor activation
nsu05410
Hypertrophic cardiomyopathy
nsu05412
Arrhythmogenic right ventricular cardiomyopathy
nsu05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110573862 (CACNA1S)
04020 Calcium signaling pathway
110573862 (CACNA1S)
04024 cAMP signaling pathway
110573862 (CACNA1S)
04022 cGMP-PKG signaling pathway
110573862 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
110573862 (CACNA1S)
04929 GnRH secretion
110573862 (CACNA1S)
04912 GnRH signaling pathway
110573862 (CACNA1S)
04921 Oxytocin signaling pathway
110573862 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
110573862 (CACNA1S)
04924 Renin secretion
110573862 (CACNA1S)
04925 Aldosterone synthesis and secretion
110573862 (CACNA1S)
04927 Cortisol synthesis and secretion
110573862 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
110573862 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
110573862 (CACNA1S)
04270 Vascular smooth muscle contraction
110573862 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
110573862 (CACNA1S)
04725 Cholinergic synapse
110573862 (CACNA1S)
04726 Serotonergic synapse
110573862 (CACNA1S)
04723 Retrograde endocannabinoid signaling
110573862 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
110573862 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
110573862 (CACNA1S)
05020 Prion disease
110573862 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
110573862 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
110573862 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
110573862 (CACNA1S)
05414 Dilated cardiomyopathy
110573862 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
110573862 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
nsu04040
]
110573862 (CACNA1S)
Ion channels [BR:
nsu04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
110573862 (CACNA1S)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
110573862
NCBI-ProteinID:
XP_021538155
UniProt:
A0A2Y9GJJ0
LinkDB
All DBs
Position
6:28666902..28734875
Genome browser
AA seq
1873 aa
AA seq
DB search
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACINIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLDEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
FRWKCHDVIKSKVFYWLVILVVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTIEML
MKIYGLGLRQYFMSIFNRFDCFVVCSGILEILLVEWGAMSPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDMEVRRSNFDNF
PQALISVFQVLTGEDWNSMMYNGIMAYGGPSYPGVLVCVYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEEKSVMAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEKECRGYYYVYKDGDPTQMELRPRQWIHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YQAIDSYKEDMGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LNKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEEMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEESTCGTNFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTIQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPP
VMANQRPLQVAEIEMEELESPVFLEDFPQDPSTNPLAHANTNNANANIAYGNSNHSNRQV
FSSIHYEREFPGQTETPAARGGAFGQPRRVLGPHSKSCVEKLKGQLTQREMPRSQAFPAP
CQRARAESPLPEERRSPTPGSLPEEATHSCRTKESSPRCQTPATAQLIQEALVRGGLDTL
AADADFVLATGQALADACQMAPEEVEVAATELLKRQGSPEGPASALGRWSLRSSLGSLDL
HQGSQETLIPPRL
NT seq
5622 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctcaccccaggatgagggcctgaggaagaaacagcccaagaagcccgtt
cctgagattctgccaaggccaccccgggccttgttctgcttgaccctccagaaccctctg
aggaaggcctgcatcaacatcgtggaatggaaaccctttgagacaatcatcttgctcacc
atctttgccaactgtgtggccctggctgtgtacctgcccatgccagaagatgacaacaac
actctgaaccttggcctggagaaactggagtatttcttcctcattgtgttctcgattgaa
gccgccatgaagatcattgcctacggcttcctcttccaccaggatgcctacttgcgcagt
ggctggaatgtgctagacttcatcattgtcttcctgggggttttcaccgtgattctggaa
caggttaacgtcatccaaagcaacacagccccaatgagcagcaaaggggctggtctggac
gtcaaggccctgagagccttccgcgtgctcagacccctccggctggtgtccggggtgccg
agcctgcaggtggtcctcaactccatcttcaaggccatgctgcccctgttccacatcgcc
ctgcttgtcctctttatggtcattatctacgccatcatcgggctggagctcttcaaaggc
aagatgcacaagacctgctacttcattgggacagatatcgtggccacagtggagaacgag
aagccctcaccctgcgccaggacgggctcggggcgcccatgcacgatcaatggcagcgag
tgtcggggcggctggccagggcccaaccacggcatcacccacttcgacaatttcggcttc
tccatgctcaccgtgtaccagtgcatcaccatggagggctggaccgacgtcctctactgg
gttaatgatgccatcgggaacgagtggccctggatctattttgtcaccctcattctgctg
ggatccttcttcattctcaacctggtgctgggtgtcctgagcggggaattcactaaggag
cgggagaaggccaagtccaggggaaccttccaaaagctccgggagaagcagcagctggag
gaggacctccggggctacatgagctggatcacgcagggcgaggtcatggacgttgaggac
ttgagagaagggaagctgtctttggatgaaggaggctccgacacagagagcctgtatgaa
attgagggcttgaacaaaatcatccagttcgttcgccactggaggcagtggaaccgcatc
tttcgctggaagtgccatgacgtgatcaagtccaaggtcttctattggctggtgatcctg
gtcgttgccctcaacaccctgtcaatcgcctccgagcaccacaaccagcctctgtggctg
acccacttgcaagacgtggccaaccgggtgctgctggccctcttcaccatcgagatgctg
atgaagatatatgggctgggactgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagtggcatcctggagatcctgctcgtggaatggggcgccatgagc
cccctgggcatctccgtgctgcgctgcatccgcctccttaggatcttcaagatcaccaag
tattggacatctctgagcaacctggtggcgtccctgctcaactccatccgctctatcgcc
tccttactgctgctgctcttcctcttcatcatcatcttcgccctgctgggcatgcagctc
ttcgggggcaggtatgacttcgaggacatggaggtgcggcgcagcaacttcgacaacttc
ccacaggccctcatcagtgtcttccaggtcctgacaggtgaagactggaactccatgatg
tacaacgggatcatggcctacggcggaccgtcctacccgggggtgctagtgtgtgtttat
ttcatcatccttttcgtctgtggcaattatatcctgctcaatgtcttcctggccatcgct
gtggacaacctggctgaggctgagagcctgacttctgcccagaaggccaaggctgaggag
agaaagcgcaggaagatgtccaagggtctcccagacaagtcagaggaggagaaatcagtg
atggccaagaagctggaacagaaacccaagggtgagggcatccctactaccgccaagctg
aaaatcgatgaatttgaatctaatgtcaatgaagtgaaggatccctacccttcagctgac
ttcccaggcgatgatgaagaagatgagcctgagatccccgtgagcccccgaccacgcccc
ctggctgagctgcagctgaaagagaaggcagtacccattccagaagccagctccttcttc
atcttcagccccaccaacaagatccgtgtcttgtgtcatcgtattgtcaatgctacctgg
ttcaccaacttcatcctgctcttcatcctgctcagcagtgctgcactggccgctgaggac
cccatccgggccgagtctgtgaggaatcagatccttgggtattttgacatcgcgttcacc
tctgtcttcactgtcgagattgtcctcaagatgaccacctacggtgccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctgctggtggtggccgtgtcactc
atctcaatgggactcgagtccagcgccatctccgtggtgaaaatcctgagggtgctgagg
gtgctcagacccctccgggccatcaacagagccaaaggcctgaagcatgtggtgcagtgc
gtgtttgtggccatccgcaccatcgggaacatcgtcctggtcaccaccctcctgcagttc
atgttcgcctgcattggcgtccagctcttcaaggggaagttcttcagctgcaatgactta
tccaagatgacggagaaggagtgcaggggctactactacgtgtacaaggatggggacccc
acgcagatggagctgcgtccacgccagtggatacacagcgatttccactttgacaatgtg
ctttcggccatgatgtcactcttcacggtgtccacctttgagggatggcctcagctactt
taccaggccatagactcatacaaggaggacatgggtcctgtctacaacaaccgggtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttt
gtgggcttcgtcatcgtcaccttccaggagcagggggagactgagtacaagaactgtgag
ctgaacaagaaccagcggcagtgtgtgcagtacgccctgaaggcccgcccgctgaggtgc
tacatccccaaaaacccataccagtaccaggtatggtatgtcgtcacctcctcctacttc
gaatacctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcattac
aaccagtcagaggagatgaaccacatctcggacatcctcaatgtggccttcaccatcatc
ttcaccctggagatggtcctcaagctcatggcgttcaaggccaggggctattttggagac
ccctggaatgtgtttgacttcttgattgtcatcggcagcatcatcgacgtcatcctcagt
gaaatcgacactttcctggcctccagcggaggactgtattgcctgggtggaggctgcggg
aacgttgacccagacgagagtgcccgcatctccagcgccttctttcgcctgttccgggtc
atgaggctgatcaagctgctgagccgggcggagggagtgcgcactctactgtggaccttc
atcaagtccttccaggccctgccctatgtggctctgctcatcgtcatgctcttcttcatc
tacgcggtcatcggcatgcagatgtttggtaagatcgccatggtggacgggacccaaata
aaccgcaacaacaacttccagacctttccacaagctgtgctgctgcttttcaggtgtgcg
acaggagaggcatggcaggagatcctgctggcctgcagctacggcaagttgtgtgaccct
gagtcagattacgccccgggtgaggagtccacgtgcggcaccaacttcgcctactactac
ttcatcagcttctacatgctctgtgctttcctgatcatcaacctctttgttgctgtcatc
atggacaactttgactacctcacacgggactggtccatcctgggccctcatcacctggat
gagttcaaggccatttgggcagagtatgacccagaggcgaagggcagaatcaaacacttg
gatgtggtgactctgctgagacggatccagccccctctgggcttcgggaagttctgcccc
caccgggtggcatgtaagcggctggtgggtatgaacatgcccttgaacagcgatggcacg
gtcaccttcaatgccacactcttcgctctggtccgcacggcactcaagatcaagacggaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctcctggaccaggtcattcctccaataggagatgatgaggtgactgta
gggaagttctacgccacgtttctcatccaggagcacttccggaagttcatgaagcgccag
gaagagtattatgggtatcggcccaagaaggacactatacagatccaggccggactgcgg
accattgaggaagaggcagccccagagatccgccgcaccatctcaggagacctgacagcg
gaagaggagctggagagagccatggtggaggctgcgatggaggaagggatattccggagg
actggaggcctctttggccaggtggacaacttcctggaaaggaccaactccctgccccct
gtcatggccaaccagagacccctccaggttgctgagatagagatggaagagctggaatcg
cctgtcttcttggaggatttccctcaagatccaagcaccaaccctcttgctcatgccaat
accaacaatgccaacgccaacatcgcctatggcaacagcaaccatagcaacaggcaggtg
ttttccagcatccactacgaaagggagttccctggacagacagagacgcctgctgccaga
ggaggagcctttggccaaccccgaagggtcctgggaccccacagcaaatcctgtgtggaa
aagctaaaaggacagctgacccagagagaaatgcccagatcccaggcatttcctgccccc
tgccagcgtgccagggccgagtctcccctgcctgaggagaggaggagccccaccccaggg
tctctgcctgaggaagcaacccacagctgtaggaccaaggagagcagtcctcggtgccag
actccagcgacagcccagctgattcaagaggctctggttcgagggggcctggacaccttg
gcggctgatgctgactttgtcctggcgaccggccaggccctggcagatgcctgccagatg
gcaccagaggaagtggaggtggcagccacagagctactgaaaagacaagggtccccagag
ggtccggccagtgcccttggacgctggagcctcagatcctctctgggcagccttgacctg
catcagggctcccaggagacgctgatcccccccaggctgtga
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integrated database retrieval system
