Neomonachus schauinslandi (Hawaiian monk seal): 110575119
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Entry
110575119 CDS
T08474
Symbol
PIK3CD
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00562
Inositol phosphate metabolism
nsu01100
Metabolic pathways
nsu01521
EGFR tyrosine kinase inhibitor resistance
nsu01522
Endocrine resistance
nsu01524
Platinum drug resistance
nsu04012
ErbB signaling pathway
nsu04014
Ras signaling pathway
nsu04015
Rap1 signaling pathway
nsu04024
cAMP signaling pathway
nsu04062
Chemokine signaling pathway
nsu04066
HIF-1 signaling pathway
nsu04068
FoxO signaling pathway
nsu04070
Phosphatidylinositol signaling system
nsu04071
Sphingolipid signaling pathway
nsu04072
Phospholipase D signaling pathway
nsu04081
Hormone signaling
nsu04140
Autophagy - animal
nsu04150
mTOR signaling pathway
nsu04151
PI3K-Akt signaling pathway
nsu04152
AMPK signaling pathway
nsu04210
Apoptosis
nsu04211
Longevity regulating pathway
nsu04213
Longevity regulating pathway - multiple species
nsu04218
Cellular senescence
nsu04360
Axon guidance
nsu04370
VEGF signaling pathway
nsu04380
Osteoclast differentiation
nsu04510
Focal adhesion
nsu04550
Signaling pathways regulating pluripotency of stem cells
nsu04611
Platelet activation
nsu04613
Neutrophil extracellular trap formation
nsu04620
Toll-like receptor signaling pathway
nsu04625
C-type lectin receptor signaling pathway
nsu04630
JAK-STAT signaling pathway
nsu04650
Natural killer cell mediated cytotoxicity
nsu04660
T cell receptor signaling pathway
nsu04662
B cell receptor signaling pathway
nsu04664
Fc epsilon RI signaling pathway
nsu04666
Fc gamma R-mediated phagocytosis
nsu04668
TNF signaling pathway
nsu04670
Leukocyte transendothelial migration
nsu04722
Neurotrophin signaling pathway
nsu04725
Cholinergic synapse
nsu04750
Inflammatory mediator regulation of TRP channels
nsu04810
Regulation of actin cytoskeleton
nsu04910
Insulin signaling pathway
nsu04914
Progesterone-mediated oocyte maturation
nsu04915
Estrogen signaling pathway
nsu04917
Prolactin signaling pathway
nsu04919
Thyroid hormone signaling pathway
nsu04923
Regulation of lipolysis in adipocytes
nsu04926
Relaxin signaling pathway
nsu04929
GnRH secretion
nsu04930
Type II diabetes mellitus
nsu04931
Insulin resistance
nsu04932
Non-alcoholic fatty liver disease
nsu04933
AGE-RAGE signaling pathway in diabetic complications
nsu04935
Growth hormone synthesis, secretion and action
nsu04960
Aldosterone-regulated sodium reabsorption
nsu04973
Carbohydrate digestion and absorption
nsu05010
Alzheimer disease
nsu05017
Spinocerebellar ataxia
nsu05020
Prion disease
nsu05100
Bacterial invasion of epithelial cells
nsu05132
Salmonella infection
nsu05135
Yersinia infection
nsu05142
Chagas disease
nsu05146
Amoebiasis
nsu05160
Hepatitis C
nsu05161
Hepatitis B
nsu05162
Measles
nsu05163
Human cytomegalovirus infection
nsu05164
Influenza A
nsu05165
Human papillomavirus infection
nsu05166
Human T-cell leukemia virus 1 infection
nsu05167
Kaposi sarcoma-associated herpesvirus infection
nsu05168
Herpes simplex virus 1 infection
nsu05169
Epstein-Barr virus infection
nsu05170
Human immunodeficiency virus 1 infection
nsu05171
Coronavirus disease - COVID-19
nsu05200
Pathways in cancer
nsu05203
Viral carcinogenesis
nsu05205
Proteoglycans in cancer
nsu05206
MicroRNAs in cancer
nsu05207
Chemical carcinogenesis - receptor activation
nsu05208
Chemical carcinogenesis - reactive oxygen species
nsu05210
Colorectal cancer
nsu05211
Renal cell carcinoma
nsu05212
Pancreatic cancer
nsu05213
Endometrial cancer
nsu05214
Glioma
nsu05215
Prostate cancer
nsu05218
Melanoma
nsu05220
Chronic myeloid leukemia
nsu05221
Acute myeloid leukemia
nsu05222
Small cell lung cancer
nsu05223
Non-small cell lung cancer
nsu05224
Breast cancer
nsu05225
Hepatocellular carcinoma
nsu05226
Gastric cancer
nsu05230
Central carbon metabolism in cancer
nsu05231
Choline metabolism in cancer
nsu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
nsu05415
Diabetic cardiomyopathy
nsu05417
Lipid and atherosclerosis
nsu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
110575119 (PIK3CD)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
110575119 (PIK3CD)
04014 Ras signaling pathway
110575119 (PIK3CD)
04015 Rap1 signaling pathway
110575119 (PIK3CD)
04370 VEGF signaling pathway
110575119 (PIK3CD)
04630 JAK-STAT signaling pathway
110575119 (PIK3CD)
04668 TNF signaling pathway
110575119 (PIK3CD)
04066 HIF-1 signaling pathway
110575119 (PIK3CD)
04068 FoxO signaling pathway
110575119 (PIK3CD)
04070 Phosphatidylinositol signaling system
110575119 (PIK3CD)
04072 Phospholipase D signaling pathway
110575119 (PIK3CD)
04071 Sphingolipid signaling pathway
110575119 (PIK3CD)
04024 cAMP signaling pathway
110575119 (PIK3CD)
04151 PI3K-Akt signaling pathway
110575119 (PIK3CD)
04152 AMPK signaling pathway
110575119 (PIK3CD)
04150 mTOR signaling pathway
110575119 (PIK3CD)
09133 Signaling molecules and interaction
04081 Hormone signaling
110575119 (PIK3CD)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110575119 (PIK3CD)
09143 Cell growth and death
04210 Apoptosis
110575119 (PIK3CD)
04218 Cellular senescence
110575119 (PIK3CD)
09144 Cellular community - eukaryotes
04510 Focal adhesion
110575119 (PIK3CD)
04550 Signaling pathways regulating pluripotency of stem cells
110575119 (PIK3CD)
09142 Cell motility
04810 Regulation of actin cytoskeleton
110575119 (PIK3CD)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
110575119 (PIK3CD)
04613 Neutrophil extracellular trap formation
110575119 (PIK3CD)
04620 Toll-like receptor signaling pathway
110575119 (PIK3CD)
04625 C-type lectin receptor signaling pathway
110575119 (PIK3CD)
04650 Natural killer cell mediated cytotoxicity
110575119 (PIK3CD)
04660 T cell receptor signaling pathway
110575119 (PIK3CD)
04662 B cell receptor signaling pathway
110575119 (PIK3CD)
04664 Fc epsilon RI signaling pathway
110575119 (PIK3CD)
04666 Fc gamma R-mediated phagocytosis
110575119 (PIK3CD)
04670 Leukocyte transendothelial migration
110575119 (PIK3CD)
04062 Chemokine signaling pathway
110575119 (PIK3CD)
09152 Endocrine system
04910 Insulin signaling pathway
110575119 (PIK3CD)
04923 Regulation of lipolysis in adipocytes
110575119 (PIK3CD)
04929 GnRH secretion
110575119 (PIK3CD)
04915 Estrogen signaling pathway
110575119 (PIK3CD)
04914 Progesterone-mediated oocyte maturation
110575119 (PIK3CD)
04917 Prolactin signaling pathway
110575119 (PIK3CD)
04926 Relaxin signaling pathway
110575119 (PIK3CD)
04935 Growth hormone synthesis, secretion and action
110575119 (PIK3CD)
04919 Thyroid hormone signaling pathway
110575119 (PIK3CD)
09154 Digestive system
04973 Carbohydrate digestion and absorption
110575119 (PIK3CD)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
110575119 (PIK3CD)
09156 Nervous system
04725 Cholinergic synapse
110575119 (PIK3CD)
04722 Neurotrophin signaling pathway
110575119 (PIK3CD)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
110575119 (PIK3CD)
09158 Development and regeneration
04360 Axon guidance
110575119 (PIK3CD)
04380 Osteoclast differentiation
110575119 (PIK3CD)
09149 Aging
04211 Longevity regulating pathway
110575119 (PIK3CD)
04213 Longevity regulating pathway - multiple species
110575119 (PIK3CD)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110575119 (PIK3CD)
05206 MicroRNAs in cancer
110575119 (PIK3CD)
05205 Proteoglycans in cancer
110575119 (PIK3CD)
05207 Chemical carcinogenesis - receptor activation
110575119 (PIK3CD)
05208 Chemical carcinogenesis - reactive oxygen species
110575119 (PIK3CD)
05203 Viral carcinogenesis
110575119 (PIK3CD)
05230 Central carbon metabolism in cancer
110575119 (PIK3CD)
05231 Choline metabolism in cancer
110575119 (PIK3CD)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110575119 (PIK3CD)
09162 Cancer: specific types
05210 Colorectal cancer
110575119 (PIK3CD)
05212 Pancreatic cancer
110575119 (PIK3CD)
05225 Hepatocellular carcinoma
110575119 (PIK3CD)
05226 Gastric cancer
110575119 (PIK3CD)
05214 Glioma
110575119 (PIK3CD)
05221 Acute myeloid leukemia
110575119 (PIK3CD)
05220 Chronic myeloid leukemia
110575119 (PIK3CD)
05218 Melanoma
110575119 (PIK3CD)
05211 Renal cell carcinoma
110575119 (PIK3CD)
05215 Prostate cancer
110575119 (PIK3CD)
05213 Endometrial cancer
110575119 (PIK3CD)
05224 Breast cancer
110575119 (PIK3CD)
05222 Small cell lung cancer
110575119 (PIK3CD)
05223 Non-small cell lung cancer
110575119 (PIK3CD)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
110575119 (PIK3CD)
05170 Human immunodeficiency virus 1 infection
110575119 (PIK3CD)
05161 Hepatitis B
110575119 (PIK3CD)
05160 Hepatitis C
110575119 (PIK3CD)
05171 Coronavirus disease - COVID-19
110575119 (PIK3CD)
05164 Influenza A
110575119 (PIK3CD)
05162 Measles
110575119 (PIK3CD)
05168 Herpes simplex virus 1 infection
110575119 (PIK3CD)
05163 Human cytomegalovirus infection
110575119 (PIK3CD)
05167 Kaposi sarcoma-associated herpesvirus infection
110575119 (PIK3CD)
05169 Epstein-Barr virus infection
110575119 (PIK3CD)
05165 Human papillomavirus infection
110575119 (PIK3CD)
09171 Infectious disease: bacterial
05132 Salmonella infection
110575119 (PIK3CD)
05135 Yersinia infection
110575119 (PIK3CD)
05100 Bacterial invasion of epithelial cells
110575119 (PIK3CD)
09174 Infectious disease: parasitic
05146 Amoebiasis
110575119 (PIK3CD)
05142 Chagas disease
110575119 (PIK3CD)
09164 Neurodegenerative disease
05010 Alzheimer disease
110575119 (PIK3CD)
05017 Spinocerebellar ataxia
110575119 (PIK3CD)
05020 Prion disease
110575119 (PIK3CD)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
110575119 (PIK3CD)
05418 Fluid shear stress and atherosclerosis
110575119 (PIK3CD)
05415 Diabetic cardiomyopathy
110575119 (PIK3CD)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
110575119 (PIK3CD)
04932 Non-alcoholic fatty liver disease
110575119 (PIK3CD)
04931 Insulin resistance
110575119 (PIK3CD)
04933 AGE-RAGE signaling pathway in diabetic complications
110575119 (PIK3CD)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110575119 (PIK3CD)
01524 Platinum drug resistance
110575119 (PIK3CD)
01522 Endocrine resistance
110575119 (PIK3CD)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
nsu04131
]
110575119 (PIK3CD)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
110575119 (PIK3CD)
Membrane trafficking [BR:
nsu04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
110575119 (PIK3CD)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3_PI4_kinase
PI3Ka
PI3K_p85B
PI3K_rbd
PI3K_C2
Motif
Other DBs
NCBI-GeneID:
110575119
NCBI-ProteinID:
XP_021539694
UniProt:
A0A2Y9GQU8
LinkDB
All DBs
Position
4:6718293..6766982
Genome browser
AA seq
1044 aa
AA seq
DB search
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLVNSQISLL
IGKGLHEFDSLHDPEVNAFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGA
GTVRVPTRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
TKPPPIPMKKPSSLSLWSLEQPFRVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRSNPNTESAAALVICLPEVAP
YPVYYPTLDKILELGRHGEHGRFSEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
RFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALSDFVKVSSQKTTKPQTKELMHLCIR
QETYLEALSNLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDTQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
NT seq
3135 nt
NT seq
+upstream
nt +downstream
nt
atgccccctggggttgactgccccatggaattctggaccaaggaggagaatcagagtgtg
gccgttgacttcctgttgcccaccggggtctatctgaacttccctgtgtcccggaatgcc
aacctcagcaccatcaagaaggtgttgtggcaccgagcccagtatgagccactcttccac
atgctcagcgaccccgaggcctatgtgttcacctgcgtcaaccagaccgcagagcagcag
gaactggaggacgagcagcggcggctctgcgacatccagcccttcctgccagtgctgcgt
ctggtggcccgagagggggacagggtgaagaagctggtcaactcgcagatcagcctcctc
atcggcaaaggcctccatgagttcgactccctgcatgaccccgaagtgaacgcctttcgc
accaagatgcgccagttctgcgaggaggcggccgcccgccggcagcagctgggctgggag
gcctggcttcagtacagcttccctctgcagctggagccctcggcccggagctggggggcc
ggcaccgtgcgggtccccacccgggccctcctggtcaacgtcaagtttgagggcagcgag
gagagcttcaccttccaggtgtccaccaaggacgtgcccctggcgctgatggcctgtgcg
ctccggaagaaggccaccgtgttccggcagcccctggtggagcagcccgaggactacacg
ctgcaggtgaacggaaagcacgagtacctgtatggcagctaccccctgtgccagttccag
tacatctgcagctgcctgcacagcgggctgaccccccacctgaccatggtgcactcctcg
tccatcctggccatgcgggacgagcagagcgaccctgccccccaagtccagaaaccacgc
accaaaccaccccccattcccatgaagaagccttcttccctgtccctgtggtccctggag
cagcctttccgcgtggagctgattcagggcagcaaagtgaatgccgatgagcggatgaag
ctggtggtgcaggctgggctcttccacggcaacgagacgctgtgcaagacggtgtccagc
tcggaggtgagcgtgtgctcggagcccgtgtggaaacagcggctggagttcgacatcaac
atctgcgacctgcctcgcatggcccgtctctgctttgcactttacgccgtgatcgagaag
gccaagaaggctcgctccaccaagaagaagtccaagaaggcggactgccccatcgcctgg
gccaacctcatgctgttcgactacaaggaccagctcaagaccggggaatgctgcctgtat
atgtggccgtccgtcccagacgagaaaggggagctgctgaaccccacgggaacagtgcgg
agtaaccccaacacggagagcgctgcggccctcgtcatctgcctccctgaggtggccccc
taccctgtgtactaccccaccctggacaagattctggagctggggcggcacggggagcac
gggcgcttcagtgaggaggagcagctacagctgcgggaaatcctggagcggcggggctcc
ggggagctgtacgagcacgagaaggacctggtgtggaagatgcggcacgaggtccaggag
cgcttccccgaggcgctggcccgcctgctgctggtcaccaagtggaacaagcacgaggat
gtggcccagatgctctacctgctgtgctcctggcccgagctgcccgtcctgagcgccctg
gagctgctggacttcagcttccccgaccgccacgtgggctccttcgccatcaagtctctg
cggaagctgacggacgatgagcttttccagtacctgctgcagctggtgcaggtgctcaag
tacgaatcctacctcgactgcgagctgaccaagttcctgctggaccgggccctggccaac
cgcaagatcggccacttcctcttctggcacctccgctccgagatgcacgtgccctccgtg
gctctgcgctttggcctcatcatggaagcttactgccggggcagcacccaccacatgaag
gtgctgatgaagcagggggaggcattgagcaagctgaaggccctgagtgacttcgtcaaa
gtgagctcccagaagaccaccaagccccagaccaaggagctgatgcacctgtgcatacgc
caggagacctacctggaggccctctccaacctgcagtccccgctggaccccagcacgctg
ctggctgaagtctgcgtggagcagtgcaccttcatggactccaagatgaagcccctgtgg
gtgatgtacagcaacgaggaggcgggcagtgacggcagtgtgggcatcatctttaagaac
ggggacgacctccgccaggacatgctgactctgcagatgatccagctcatggatgttctg
tggaagcaggagggactggacctgaggatgaccccctatggctgcctctccacgggggac
cgcacaggcctcatcgaggtggtgcttcactcagacaccatcgccaacatccagctcaac
aagagcaacatggcggccacagcggccttcaacaaggatgccctgctcaactggctcaag
tccaagaaccctggggaggccttggatcgagccatcgaggagtttaccctctcttgcgcc
ggctactgcgtggccacttacgtgctgggcatcggtgatcggcacagcgacaacatcatg
atccgcgagaatgggcagctgttccacattgattttggccactttctggggaatttcaag
accaagtttggaatcaaccgtgagcgagtcccgttcatcctcacgtatgactttgtgcac
gtgatccagcaggggaaaacgaataacagtgagaagtttgaaagattccggggttactgt
gagcgagcctacaccatcctgcggcgtcacgggctgctcttccttcacctcttcgccctg
atgcgggccgctggcctgccggagctcagctgctctaaagacacccagtatctcaaggac
tctctggcgttggggaagactgaggaggaggctctaaagcacttccgagtgaagtttaac
gaagccctccgggagagctggaagaccaaagtgaactggctggcccacaatgtgtccaaa
gataacaggcaatag
DBGET
integrated database retrieval system