KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110575769
Entry
110575769         CDS       T08474                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2 isoform X1
  KO
K10140  DNA damage-binding protein 2
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu03420  Nucleotide excision repair
nsu04115  p53 signaling pathway
nsu04120  Ubiquitin mediated proteolysis
nsu05161  Hepatitis B
nsu05169  Epstein-Barr virus infection
nsu05200  Pathways in cancer
nsu05202  Transcriptional misregulation in cancer
nsu05210  Colorectal cancer
nsu05212  Pancreatic cancer
nsu05213  Endometrial cancer
nsu05214  Glioma
nsu05216  Thyroid cancer
nsu05217  Basal cell carcinoma
nsu05218  Melanoma
nsu05220  Chronic myeloid leukemia
nsu05222  Small cell lung cancer
nsu05223  Non-small cell lung cancer
nsu05224  Breast cancer
nsu05225  Hepatocellular carcinoma
nsu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    110575769 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    110575769 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    110575769 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110575769 (DDB2)
   05202 Transcriptional misregulation in cancer
    110575769 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    110575769 (DDB2)
   05212 Pancreatic cancer
    110575769 (DDB2)
   05225 Hepatocellular carcinoma
    110575769 (DDB2)
   05226 Gastric cancer
    110575769 (DDB2)
   05214 Glioma
    110575769 (DDB2)
   05216 Thyroid cancer
    110575769 (DDB2)
   05220 Chronic myeloid leukemia
    110575769 (DDB2)
   05217 Basal cell carcinoma
    110575769 (DDB2)
   05218 Melanoma
    110575769 (DDB2)
   05213 Endometrial cancer
    110575769 (DDB2)
   05224 Breast cancer
    110575769 (DDB2)
   05222 Small cell lung cancer
    110575769 (DDB2)
   05223 Non-small cell lung cancer
    110575769 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    110575769 (DDB2)
   05169 Epstein-Barr virus infection
    110575769 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:nsu04121]
    110575769 (DDB2)
   03400 DNA repair and recombination proteins [BR:nsu03400]
    110575769 (DDB2)
Ubiquitin system [BR:nsu04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     110575769 (DDB2)
DNA repair and recombination proteins [BR:nsu03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      110575769 (DDB2)
SSDB
Motif
Pfam: WD40_CDC20-Fz WD40 WD40_Prp19 WD40_WDHD1_1st Beta-prop_EML_2 Beta-prop_WDR75_1st WDR55 Beta-prop_RIG_2nd Beta-prop_WDR90_POC16_2nd Beta-prop_IFT140_1st Beta-prop_EIPR1 Beta-prop_WDR19_1st EIF3I Beta-prop_TEP1_2nd WD40_RFWD3 Beta-prop_TEP1_C Beta-prop_CAF1B_HIR1 NBCH_WD40 WD40_MABP1-WDR62_2nd Beta-prop_HPS5 WD_LRWD1 Beta-prop_Vps41 EF-hand_1
Other DBs
NCBI-GeneID: 110575769
NCBI-ProteinID: XP_044775382
UniProt: A0A8M1MNG0
LinkDB
Position
11:complement(14863738..14883376)
AA seq 426 aa
MAPRKRPETQKTLEVAVRPKSKRSRSPRELEPEAKKLCVKGPGSSRRFDSGCLWAGLASL
QVRPSCSIVRALHHHKLGNAVRPSLQQGLQQAFLHSLASYRIFQKAAPFDRRATSLAWHP
THPSTLAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLDTNQFFTSSMEGTT
RLQDFKGNTLRVFTSSGTCNFWFCSLDVSARSRMVVTGDNVGHVILLNMDGRELWNLRMH
KKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKSSFLHSLPHSHPVNAACFSPDGA
QLLTTDQKSELRVYSASQWDCPPSLIPHPHRHFQHLTPIKATWHPRYNLVVVGRYPDPNF
KSCTPHELRTIDVFDGNSGKMMYQLYDPESSGIISLNEFNPMGDTLASVMGYHILIWSQE
EAGMRT
NT seq 1281 nt   +upstreamnt  +downstreamnt
atggctcctaggaaacgcccagaaacccagaagaccctcgaggtggcagtgcgccccaag
agcaagaggagcagaagcccccgggagctggagcccgaggccaagaagctctgtgtgaag
ggccccggttctagcagaagatttgactcaggctgcctttgggcggggttggctagcctg
caggtccggccatcatgcagcatcgtcagggccctgcaccaccataagctgggcaatgct
gtccggccatcactacagcagggtctccagcaggcctttctgcactctctggcttcttac
cggatattccaaaaggctgccccctttgacaggagggccacatccttggcatggcaccca
actcaccccagcaccctggctgtgggttccaaagggggagatatcatgctctggaacttt
ggcataaaggacaaacctaccttcattaaagggatcggagctggagggagcatcactggg
ctgaagtttaaccctcttgataccaaccagtttttcacctcctcaatggagggaacaact
aggctgcaagactttaaaggcaacactctccgagtttttaccagctcaggcacctgcaac
ttctggttttgcagcctggatgtgtctgccagaagccgaatggtggtcacgggagacaat
gtggggcacgtgatcctgctcaacatggatggcagggagctttggaatctgagaatgcac
aaaaagaaagtgacccatgtggccctgaacccatgctgtgattggttcctggccacagcc
tctgtagaccaaacagtgaaaatctgggacctgcgccaggttagagggaaatccagcttc
ctccattcgctgccgcatagccatcctgtcaacgcagcttgtttcagtcctgatggagcc
cagctcctgaccactgaccagaagagtgagctccgggtttactcggcctcccagtgggac
tgccccccaagcctgatcccacaccctcaccgccacttccagcacctgacgcccatcaag
gcaacctggcatcctcggtacaacctcgttgtcgtgggccgatacccagatcctaatttc
aaaagctgtaccccccatgaattaaggacgatcgatgtgtttgatggaaactcagggaag
atgatgtatcagctctatgatccagaatcttctggtatcatttcgctcaatgagttcaat
cccatgggggacacgctggcctctgtgatgggttatcacattctcatttggagccaggag
gaagctgggatgcggacatga

DBGET integrated database retrieval system