KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110577823
Entry
110577823         CDS       T08474                                 
Symbol
GLS2
Name
(RefSeq) glutaminase liver isoform, mitochondrial
  KO
K01425  glutaminase [EC:3.5.1.2]
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00220  Arginine biosynthesis
nsu00250  Alanine, aspartate and glutamate metabolism
nsu00470  D-Amino acid metabolism
nsu01100  Metabolic pathways
nsu04724  Glutamatergic synapse
nsu04727  GABAergic synapse
nsu04964  Proximal tubule bicarbonate reclamation
nsu05206  MicroRNAs in cancer
nsu05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    110577823 (GLS2)
   00220 Arginine biosynthesis
    110577823 (GLS2)
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    110577823 (GLS2)
 09150 Organismal Systems
  09155 Excretory system
   04964 Proximal tubule bicarbonate reclamation
    110577823 (GLS2)
  09156 Nervous system
   04724 Glutamatergic synapse
    110577823 (GLS2)
   04727 GABAergic synapse
    110577823 (GLS2)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    110577823 (GLS2)
   05230 Central carbon metabolism in cancer
    110577823 (GLS2)
Enzymes [BR:nsu01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.2  glutaminase
     110577823 (GLS2)
SSDB
Motif
Pfam: Glutaminase EF-hand_14 Ank_4 Ank_2 Ank Ank_5 Ank_3 Ank_KRIT1
Other DBs
NCBI-GeneID: 110577823
NCBI-ProteinID: XP_021542935
UniProt: A0A2Y9GYQ4
LinkDB
Position
5:57854765..57868038
AA seq 602 aa
MRSMRALQNALSGAGSHCWLGGWGHLSRSPLLGGGVRHHLSEAAALGRETPHSHQPQHQD
HDSSESGMLSRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLRDCMSQMRRMVR
ESSSGGLLDRDLFQKCVSSNIVLLTQAFRKKFVIPDFEEFTSHVDRIFEDAKELTGGKVA
AYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTDYVHK
FVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAG
NEYMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGEDMMAALDLYFQLCSVEVTCESG
SVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGA
ILLVVPNVMGMMCLSPPLDKLGNSRRGISFCQKLVSLFNFHNYDNLRHCARKLDPRREGG
EVRNKTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIE
ACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYQDSYTPSETQAEAEAEALSKENLES
MV
NT seq 1809 nt   +upstreamnt  +downstreamnt
atgcgctctatgagggctctgcagaacgcgctgagcggggccggcagtcactgctggctg
ggaggctggggtcacctgagccggagccctctccttggcgggggcgtccggcaccacctc
agtgaggccgcggcgctgggcagggagacgccgcacagccaccagccgcagcaccaggat
catgactcctcagagagtggcatgctatcccgcctgggtgatctgctcttctacactatt
gctgaaggacaggaacgaattcctatccacaagttcactactgcactgaaggccactgga
ctgcagacatcagatccccggctccgggactgcatgagccagatgcgccgcatggttcga
gagtccagcagtggtggcctcttggaccgagatctcttccaaaagtgtgtgagcagcaac
attgtgctcctgacccaggcattccgaaagaagtttgtcattcctgattttgaggagttc
acgagccatgtggatcgcatctttgaggatgccaaagagctcactggaggcaaagtggcg
gcctatatccctcagctggccaagtccaatccagacctgtggggcgtctccctgtgcact
gtggatggtcagcggcactccgtgggccacacaaagattcccttctgcctgcagtcctgt
gtgaagcccctcacctatgccatctccatcagcaccctaggcactgactacgtgcacaag
tttgtgggcaaggagcccagtggcctacgctacaacaagctctccctcaatgaggaagga
atcccccataaccccatggtcaatgctggcgccattgtcgtgagctccctgatcaagatg
gactgtaacaaagcagagaagtttgattttgtgttacagtatctgaacaaaatggctggg
aacgaatacatgggtttcagcaatgccacattccagtcagagaaggaaacaggggatcgg
aattatgccatcggctattatctaaaggaaaagaagtgctttcctaagggggaggacatg
atggctgctcttgatctctatttccagctgtgctccgtggaggtgacctgtgagtcaggc
agtgtcatggcagccaccctggccaacggcgggatctgccccatcacaggagagagtgta
ctgagtgctgaagcagtgcgcaacaccctcagcctcatgcactcctgcggcatgtacgac
ttctcaggccagtttgctttccatgtgggcctgccagccaagtcagctgtgtcaggagcc
atcctcctagtggtacccaatgtaatgggaatgatgtgtctgtcacctccattggacaaa
ctagggaacagccgtaggggcatcagcttctgccagaagttggtgtctctcttcaatttc
cacaactacgataacctgaggcactgtgctcgcaagttagacccacggcgtgaaggggga
gaagttcggaacaagactgtggtgaacctgttatttgctgcctatagtggagatgtctca
gcccttcgaaggtttgccttgtcagccatggacatggaacagaaagactatgactcccgc
acagccctgcatgttgctgcagctgaaggacacatcgaagttgttaaattcctgattgaa
gcttgcaaagtgaatccttttgtcaaggataggtggggcaacattcccctggatgatgct
gtgcagttcaaccacctggaggtggtgaaactgcttcaggattaccaggactcctacaca
ccatcggagactcaggctgaggcagaggctgaggccctgtccaaagagaacttagagagc
atggtgtga

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