KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110580843
Entry
110580843         CDS       T08474                                 
Symbol
MGST1
Name
(RefSeq) microsomal glutathione S-transferase 1 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00480  Glutathione metabolism
nsu00980  Metabolism of xenobiotics by cytochrome P450
nsu00982  Drug metabolism - cytochrome P450
nsu00983  Drug metabolism - other enzymes
nsu01100  Metabolic pathways
nsu01524  Platinum drug resistance
nsu05200  Pathways in cancer
nsu05204  Chemical carcinogenesis - DNA adducts
nsu05207  Chemical carcinogenesis - receptor activation
nsu05208  Chemical carcinogenesis - reactive oxygen species
nsu05225  Hepatocellular carcinoma
nsu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    110580843 (MGST1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    110580843 (MGST1)
   00982 Drug metabolism - cytochrome P450
    110580843 (MGST1)
   00983 Drug metabolism - other enzymes
    110580843 (MGST1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110580843 (MGST1)
   05204 Chemical carcinogenesis - DNA adducts
    110580843 (MGST1)
   05207 Chemical carcinogenesis - receptor activation
    110580843 (MGST1)
   05208 Chemical carcinogenesis - reactive oxygen species
    110580843 (MGST1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    110580843 (MGST1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    110580843 (MGST1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    110580843 (MGST1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:nsu02000]
    110580843 (MGST1)
Enzymes [BR:nsu01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     110580843 (MGST1)
Transporters [BR:nsu02000]
 Other transporters
  Pores ion channels [TC:1]
   110580843 (MGST1)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 110580843
NCBI-ProteinID: XP_021546168
EnsemblRapid: ENSNSCG00000015173
UniProt: A0A2Y9H3G8
LinkDB
Position
5:complement(88595306..88625398)
AA seq 164 aa
MRFQTKIEKMVDLTELMENEVFKAYASYTTIILSKMMFMSTATAFYRLTRKVFANPEDCA
GFGKGENAKKYLRTDDRVERVRRAHLNDLENIVPFLGIGLLYSLSGPDLSTALLHFRLFV
GARIYHTIAYLTPLPQPNRALAFFVGYGVTFSMAYRLLKSQLYL
NT seq 495 nt   +upstreamnt  +downstreamnt
atgagattccagaccaaaattgaaaaaatggttgacctcactgagctaatggaaaatgaa
gtattcaaggcctatgcttcctatacaacgattattctttcaaaaatgatgtttatgagt
actgcaactgcattctatagattgacaagaaaggtttttgccaacccagaagactgtgct
ggctttggcaagggagaaaatgccaagaagtatcttcggacagatgacagagtggaacgt
gtacggagagctcacctgaatgaccttgaaaatattgtgccatttcttggtattggcctt
ctgtattccttgagtggtccagatctctctacggccctcctgcacttcagactctttgtt
ggagcacggatctaccacacgatcgcgtatttgacaccccttccccagccaaatcgggcg
ttggctttctttgttggatatggagttactttttcaatggcttacaggttgctgaaaagc
caattgtacttgtaa

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