Neomonachus schauinslandi (Hawaiian monk seal): 110581833
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Entry
110581833 CDS
T08474
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP isoform X1
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu03060
Protein export
nsu04141
Protein processing in endoplasmic reticulum
nsu04612
Antigen processing and presentation
nsu04918
Thyroid hormone synthesis
nsu05012
Parkinson disease
nsu05014
Amyotrophic lateral sclerosis
nsu05020
Prion disease
nsu05022
Pathways of neurodegeneration - multiple diseases
nsu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
110581833 (HSPA5)
04141 Protein processing in endoplasmic reticulum
110581833 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
110581833 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
110581833 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
110581833 (HSPA5)
05014 Amyotrophic lateral sclerosis
110581833 (HSPA5)
05020 Prion disease
110581833 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
110581833 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
110581833 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
nsu03110
]
110581833 (HSPA5)
04131 Membrane trafficking [BR:
nsu04131
]
110581833 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
nsu04147
]
110581833 (HSPA5)
Enzymes [BR:
nsu01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
110581833 (HSPA5)
Chaperones and folding catalysts [BR:
nsu03110
]
Heat shock proteins
HSP70 / DNAK
110581833 (HSPA5)
Membrane trafficking [BR:
nsu04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
110581833 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
110581833 (HSPA5)
Exosome [BR:
nsu04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
110581833 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
110581833 (HSPA5)
Exosomal proteins of colorectal cancer cells
110581833 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
110581833
NCBI-ProteinID:
XP_021547404
UniProt:
A0A2Y9HDP3
LinkDB
All DBs
Position
13:complement(83720205..83724624)
Genome browser
AA seq
654 aa
AA seq
DB search
MKLSLVAAVLLLLGAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGDEEPADKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgtccttggtggctgcggtgctgctgctgctcggcgcggcgcgggccgaggag
gaggacaagaaggaagacgtgggcacggtggtcggtatcgacctggggaccacctactct
tgcgtcggggtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaaccgc
atcacgccgtcttatgtggccttcactcctgaaggggagcgtctgatcggcgatgcagcc
aagaaccagctcacctccaaccctgagaacacggtcttcgacgccaagcggctcatcggc
cgcacatggaacgacccgtccgtgcaacaggacatcaagttcttgcctttcaaggtggtt
gagaagaagactaaaccatacattcaagttgatattggaggtgggcaaacaaagacattt
gctcctgaagaaatttctgccatggttctcaccaaaatgaaggaaactgcagaggcttat
ttgggaaagaaggttacccatgcagttgttactgtaccagcctatttcaatgatgcccaa
cgccaggcaaccaaagatgctggaactattgctggattgaatgtcatgaggatcatcaat
gagcctacagcagctgctattgcttatggcttggataagagggaaggggagaagaatatc
ctggtgtttgacctgggtggtggaacttttgatgtgtctcttctcaccattgacaatggt
gtcttcgaagtcgtggctactaatggagatactcatctgggtggagaagactttgaccaa
cgtgtcatggaacacttcatcaaactctacaaaaagaagactggcaaagatgttaggaaa
gacaacagagctgtgcagaaactccggcgggaggtagaaaaagccaaacgggccctgtcc
tctcaacatcaagcaagaattgaaattgagtctttctatgaaggagaagacttctctgag
actctgacccgggccaaatttgaagagctaaatatggacctgttccgttctaccatgaag
cctgttcagaaggtgctggaggattctgacttaaagaagtctgatattgatgaaattgtt
cttgttggtggctctactcgaatcccaaagattcaacaactggttaaagagttcttcaat
ggcaaggagccatcccgtggcatcaacccagatgaggctgtagcatatggtgctgctgtc
caggctggcgtactctctggtgatcaagatacaggtgacctggtactgcttgatgtatgt
ccccttacacttggtattgaaactgtgggaggtgtcatgaccaaactgattccaaggaac
actgtggtgcccaccaagaagtctcagatcttttctacagcttctgataaccaaccaact
gttacaatcaaggtctatgaaggtgaacgacccctgacaaaagacaatcaccttctggga
acttttgacctgactggaattcctcctgctccccgtggggtcccacagattgaagtcacc
tttgagatagatgtgaatggcattcttagagtgacagctgaagacaaaggtacaggcaac
aaaaataagattacaattaccaatgaccaaaatcgcctgacacctgaagaaattgaaagg
atggttaatgatgctgagaagtttgccgaggaagacaaaaagctcaaggagcgcattgat
accagaaatgaattagaaagctatgcctattctctaaagaatcagattggagataaagaa
aagctgggaggtaaactctcctctgaagataaggagaccatggaaaaagctgtagaggaa
aagattgaatggctagaaagtcaccaagatgctgacattgaagatttcaaagctaaaaag
aaggaactagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggccct
cccccaactggtgatgaggaaccagcagacaaagatgagttgtag
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