Neomonachus schauinslandi (Hawaiian monk seal): 110582708
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Entry
110582708 CDS
T08474
Symbol
MYLK
Name
(RefSeq) LOW QUALITY PROTEIN: myosin light chain kinase, smooth muscle
KO
K00907
myosin-light-chain kinase [EC:
2.7.11.18
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04020
Calcium signaling pathway
nsu04022
cGMP-PKG signaling pathway
nsu04270
Vascular smooth muscle contraction
nsu04371
Apelin signaling pathway
nsu04510
Focal adhesion
nsu04611
Platelet activation
nsu04810
Regulation of actin cytoskeleton
nsu04921
Oxytocin signaling pathway
nsu04971
Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
110582708 (MYLK)
04020 Calcium signaling pathway
110582708 (MYLK)
04022 cGMP-PKG signaling pathway
110582708 (MYLK)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
110582708 (MYLK)
09142 Cell motility
04810 Regulation of actin cytoskeleton
110582708 (MYLK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
110582708 (MYLK)
09152 Endocrine system
04921 Oxytocin signaling pathway
110582708 (MYLK)
09153 Circulatory system
04270 Vascular smooth muscle contraction
110582708 (MYLK)
09154 Digestive system
04971 Gastric acid secretion
110582708 (MYLK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nsu01001
]
110582708 (MYLK)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.18 myosin-light-chain kinase
110582708 (MYLK)
Protein kinases [BR:
nsu01001
]
Serine/threonine kinases: CAMK group
MLCK family
110582708 (MYLK)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
I-set
Ig_3
Ig_2
ig
Pkinase
23ISL
V-set
PK_Tyr_Ser-Thr
C2-set_2
fn3
Ig_4
Ig_DSCAM-DSCAML_C
Kinase-like
Kdo
AvrM_N
Pur_ac_phosph_N
Motif
Other DBs
NCBI-GeneID:
110582708
NCBI-ProteinID:
XP_044775704
UniProt:
A0A8M1MXW6
LinkDB
All DBs
Position
1:complement(67025160..67228044)
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AA seq
1960 aa
AA seq
DB search
MGDVKLAASTQVSKTSVSVDHLRVGSMSLTEAPAFIVPPRNLCIREGATAKFEGRVRGYP
EPHVTWHRNGQPITSGGRFLLDCGVRGAFSLVIRAVCEEDKGKYTCEAANDSGARQVTVE
LTVEGGFMKKHGQPAVSKTLGFAAPAVETRPSIWGECPPKFATKLGRAIVKEGQMGRFSC
KITGRPQPQVTWLKGEVPLQPSARVSMSEKNGVQVLEIHEVSCDDVGVYTCLVVNGSGKA
SMSAELSIQGLDNASRSLVRGTKAANSDIRKEVTNGTTQGPKLDSLASAAERKNCSSTQR
GGSPTWATSSQPPPLRESQPESSGDPPRKALRSPVLQKTSSTITLQAAKVQPEPRALVSG
APSSSGEERERPAASPIAILPTRQFGLGSQEVISKVATRKIPTESQRDSTFPKFESKPQS
QEVSEDQTIKFRCEVSGTPKPEVTWFLEGAPVRIREGMVEVYEEGGCHYLCLLRARARDS
GTYSCTASNVRGQMSCSWTLLVKRLAATEVAPSFSRVLKDCTVVEGQDFVLQCSVQGTPV
PQITWLLNEQPIQYAHSSCEAGVAELHIQDALPEDDGTYTCLAKNTVGQVSCSARVTVHE
KKSDRKSGYPLPAAPSKPVAPLFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHDGNE
IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTRAVLVVQEPQDGTQPW
FISKPRSVTTSLGQRVLMSCAIAGDPFPTVHWLRDGKALSKDTGHFEVLQNEDVFTLVLK
DVQPWHAGQYEILLKNRVGECSCQVSLMLQSSPGRAPLRGREPVSCEGLCSQGAGAHGAG
GDCYGTLRPGWPARGQGWPEEEDGEDVRGLLKRRVETRQHTEEAIRQQEVEQLDFRDLLG
KKVSTKTVSEEDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT
PKTPVPEKAPLPKPATPDFRSVLGSKKKLPAENGSNNAEALNAKAAESPKAVSNAQPLGS
LKPLGNAKPAETLRPVGNAKPAEPTKPVDNTKLAETLKPIGNAKPAETPKPMGNAKPAXX
XXPMGNAKPAETPKPMGNAKPAETPKPAGKELKKEVKNDVNCKRGHAGATDNENRSENQG
TAPTFKEKLQDVRVTEGEKLLLQCQVSSDPPATITWTLNGKTLKTTKFIILSQEGSLCSV
SIEKALPEDRGLYKCIAKNRAGQAECSCQVTVDDAPTKENAKAPEMKARRPKSSLPPVLG
TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVAGTQPITCTWMKFR
KQIQESEHIKVENSENGSRLTILATRHEHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPA
GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSVEIWDSVDKTWKELATCRSTSFNVQDLL
PDREYKFRVRAINVYGTSEPSQESELTAVGEKPEEPKDEVEVSDDDEKEPEISYRNVTVN
TEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKIWAGKFFKAYSAKEKENIRQEISIMNC
LHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIQYMRQISEGVEY
IHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARKLENAGSLKVLFGTPEFVAPEVINY
EPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDF
ISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAI
GRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTI
RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD
DDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEEE
NT seq
5883 nt
NT seq
+upstream
nt +downstream
nt
atgggggatgtgaagctggctgcctcaacccaggtttctaaaacctccgtcagtgtggat
cacctgagagtcggttccatgtccctgaccgaggcccctgctttcattgtgccccctcgg
aacctctgcatcagagaaggagccaccgccaagtttgaagggagggtccggggttaccca
gagccccacgtgacatggcaccgaaatgggcaacccatcaccagcgggggccgcttcctg
ctggattgtggtgtccggggagctttcagccttgtgattcgtgctgtctgtgaggaagac
aagggaaagtatacctgtgaagccgccaatgatagtggtgcccgccaggtgacagtggag
ttgacggtggaagggggctttatgaagaagcatggtcagcctgctgtttccaaaaccttg
ggatttgcagcccctgccgtggagacccgtcctagcatctggggagagtgcccaccaaag
tttgctaccaagttgggccgagccatagtcaaagaaggacagatgggacggttttcctgc
aagatcactggccggccccaaccacaggtcacctggctcaagggagaggttcccctgcag
ccaagtgcccgtgtgtctatgtctgagaagaatggggtacaagttctggaaatccatgag
gtcagctgcgatgacgtgggagtgtacacgtgcctggtggtgaatgggtcggggaaggcc
tccatgtcggccgagctttctatccaaggtttggacaatgccagtaggtcattggtgaga
ggaacaaaggcagccaattcagatatcaggaaggaagtgaccaatggaaccacacagggg
ccgaaactggacagcctcgcgtctgctgccgagagaaagaactgctccagtacccagaga
gggggctccccgacctgggccacaagtagccagcctccacccctgcgggagtcccagcca
gagtcgtccggggacccaccgaggaaggccctgaggagccccgtcctacaaaagacttcc
agcaccatcaccctgcaggctgcaaaagtccagccagaaccaagagcactggtctcgggt
gccccctcatcttctggagaagagagggagaggccagctgcgtcccccatagccatcctc
cccaccaggcagtttggcctgggaagccaggaggtgataagcaaggttgctacaaggaaa
atccccacggagagccagagggattccaccttccccaaatttgagagcaaaccccaaagc
caggaagtcagtgaagatcagacaatcaagttcagatgcgaggtttcagggaccccgaag
cctgaagtgacctggttcctggaaggtgcccccgtgaggattcgagaaggcatggttgag
gtttatgaagaaggcggatgccattacctctgcctgctgagagcgcgggccagagacagt
gggacctatagctgcacggcctccaatgtccgaggccagatgtcctgcagttggaccctc
ctggtgaaacggctggccgcgacggaggtggcaccctcattctccagggtcctgaaggac
tgcactgtcgtcgagggccaggactttgtgctgcagtgctctgtgcaggggaccccggtc
ccccaaatcacttggctgctcaatgagcagcccatccagtacgctcactcatcctgcgag
gccggtgtggccgagctccacatccaggacgccctgccggaagatgatggcacttacacc
tgtctggccaagaacaccgtggggcaggtgtcctgcagcgcccgggtcactgtccatgaa
aagaagagcgacaggaagagcgggtaccctctgcccgcggctcccagcaagccggtcgcg
cccctcttcctgcagggcctctccgacctcaaagtcatggatggaagccaggtcaccatg
acagtccaggtgtcagggaacccgccccctgaggtcatctggcttcacgatgggaatgag
atccaggagtcggaggacttccactttgagcagagaggcactcagcacagcctttgtatc
caggaagtgttcccggaggacacgggcacgtacacctgtgaagcctggaacagcgccgga
gaagtccgcacccgggcggtgcttgtggtacaagagcctcaggacggcacccagccctgg
ttcatcagcaagccccgctcagtgacaacctccctgggccagcgtgtcctcatgtcctgt
gccatcgctggggaccccttccccactgtgcactggctgcgcgacggcaaagccctctcc
aaagacactggccacttcgaggtgctacagaatgaggacgtgttcacgctggttctaaag
gatgtgcagccttggcatgccggccagtatgagatcctgctcaagaaccgggttggcgaa
tgcagttgccaggtgtcactgatgctacagagcagccccggcagagcgcccctgcggggg
agggagcctgtcagctgtgagggcctctgcagccagggagccggtgctcatggtgctggc
ggtgactgctatgggaccctgaggcctggctggccagcgagagggcagggttggccagag
gaggaagacggtgaggacgtgcggggcttgctgaagaggcgcgtggagacccggcagcat
actgaggaggccatccgccagcaggaggtagaacagctagacttccgtgacctcctgggg
aagaaggtgagtaccaagaccgtgtcagaagaagacctcaaggagatcccagctgagcag
atggatttccgcgccaacctgcagcggcaggtgaagcctaagactgtgtcagaggaagag
aggaaggtgcacagccctcagcaagtcgacttccgctcggtcctggccaaaaaggggact
cctaagaccccggtgcctgagaaggcaccacttcccaaacctgccaccccggacttccgc
tccgtgttaggcagcaagaaaaaattaccagcagagaatggtagcaacaatgctgaggcc
ttgaatgccaaggcagcagaaagtcccaaggccgtgagcaatgcccagcctttagggtcc
ctgaaacccttgggcaatgccaagcctgctgagaccctaagacctgtgggcaatgccaag
cctgcggagcccacgaaacctgtggacaacacaaagcttgctgagacgctgaaacccata
ggcaatgccaagcctgctgagaccccaaaacccatgggcaacgccaagcctgcnnnnnnn
nnnnaacccatgggcaacgccaagcctgctgagaccccaaaacccatgggtaacgccaag
cctgctgagaccccaaaaccagctgggaaagaactcaagaaggaggttaagaatgatgtg
aactgtaagagggggcatgcaggagccacagataatgagaacaggtcagagaaccaaggg
acagccccaaccttcaaggagaagctacaagatgtccgtgtgacagagggcgagaagctg
ctactccagtgtcaggtgtcctctgaccccccagccaccatcacctggacgctgaatgga
aagacactcaagaccaccaagttcatcatcctctcccaagaaggctcactgtgctctgtc
tccatcgagaaggcactgcccgaggacagaggcttatacaagtgcatagccaagaatcgc
gccggccaggctgagtgctcctgccaagtcaccgtggacgatgctcccaccaaggagaat
gccaaggccccagagatgaaagcccggaggcccaagagctctcttcctcccgtgctagga
acagagagtgatgcaactgtgaaaaagaaacccgcccccaagacacctccgaaggcagcc
atgccccctcaaatcatccagtttcctgaggaccaaaaggtgcgcgcaggagagtccgtg
gagctgtttggtaaagtggcaggcacccagcccatcacctgtacttggatgaagttccga
aagcagatccaggagagcgagcacatcaaggtggagaacagcgagaatggcagtaggctc
accatcctagccacgcgccacgaacactgtggctgctacactctggtggtggagaacaag
ctgggcagcaggcaggcccaggtcaacctcactgtcgtggacaagccagaccccccagcc
ggcacgccttgcgcctctgacatccggagctcctcgttgaccctgtcctggtatggctcc
tcatatgatgggggcagtgctgtgcagtcctacagtgtcgagatctgggactcggtggac
aaaacgtggaaggaactagccacatgccgcagcacctcttttaacgtccaggacctgctg
cctgaccgagagtataaattccgtgtgcgcgccatcaacgtgtatggaaccagtgagccg
agccaggagtctgaactcacagcagtgggagaaaaaccagaggagccaaaggacgaagtg
gaggtgtcagatgatgatgagaaggaacctgagatcagctaccggaacgtgaccgtcaac
actgaacaaaaagtgtctgacttctatgacatcgaagagagactaggctctgggaaattt
ggacaggtctttcgactcgtagaaaagaaaactagaaaaatctgggcagggaaattcttc
aaggcatattccgcaaaagagaaagagaatatccggcaggagatcagcatcatgaactgc
ctccaccaccccaagctggtccagtgtgtggatgccttcgaagaaaaggccaacattgtc
atggtcctggagatcgtgtcggggggtgagctgttcgagcgcatcattgacgaggacttc
gagctgacggagcgggagtgcatccagtacatgaggcagatatcggagggggtggagtac
atccacaagcagggcatcgtccacctggacctcaagcccgagaacatcatgtgtgtcaat
aagaccggcaccagaatcaagctcatcgacttcggtctggccagaaagctggagaatgca
gggtctctgaaggtcctctttggcaccccagagtttgtggcaccggaagtgatcaactat
gagcccatcggctatgccacggacatgtggagtatcggagtcatctgctacatcctggtt
agtggactttcccccttcatgggtgacaacgataatgaaaccctagccaacgttacctca
gccacctgggacttcgatgacgaagcgttcgatgagatctctgatgatgccaaggatttt
atcagcaatttgctgaagaaagatatgaaaaaccgcctggactgcacccagtgccttcag
catccatggctaatgaaagacaccaagaacatggaggccaagaaactctccaaggaccgg
atgaagaagtacatggcaagaaggaaatggcagaaaacgggcaatgctgtgagagccatt
ggaagactgtcctctatggcaatgatctcagggctcagtggcaggaaatcctcaacaggg
tcaccaaccagcccgcttaatgcagaaaaattagaatctgaagaagatgtgtctcaagct
ttccttgaggctgttgcagaggaaaagccccatgtaaaaccctatttctctaagaccatc
cgtgatttagaagttgtggagggaagcgctgctagatttgactgcaagattgaaggatac
ccagaccctgaagttgtctggttcaaagatgaccagtcaatccgggagtcccgccacttc
cagatagactacgacgaggacgggaactgctctttaatcattagcgatgtttgcggggat
gacgatgccaagtacacctgcaaggctgtcaacagtctcggggaagccacctgcacagcg
gagctcattgtggagaccatggaggaaggggaaggggaaggggaagaagaagaggaagag
tga
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