Neomonachus schauinslandi (Hawaiian monk seal): 110584421
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Entry
110584421 CDS
T08474
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu01521
EGFR tyrosine kinase inhibitor resistance
nsu04062
Chemokine signaling pathway
nsu04081
Hormone signaling
nsu04148
Efferocytosis
nsu04151
PI3K-Akt signaling pathway
nsu04217
Necroptosis
nsu04550
Signaling pathways regulating pluripotency of stem cells
nsu04630
JAK-STAT signaling pathway
nsu04658
Th1 and Th2 cell differentiation
nsu04659
Th17 cell differentiation
nsu04725
Cholinergic synapse
nsu04917
Prolactin signaling pathway
nsu04920
Adipocytokine signaling pathway
nsu04933
AGE-RAGE signaling pathway in diabetic complications
nsu04935
Growth hormone synthesis, secretion and action
nsu05140
Leishmaniasis
nsu05145
Toxoplasmosis
nsu05152
Tuberculosis
nsu05161
Hepatitis B
nsu05164
Influenza A
nsu05167
Kaposi sarcoma-associated herpesvirus infection
nsu05168
Herpes simplex virus 1 infection
nsu05200
Pathways in cancer
nsu05207
Chemical carcinogenesis - receptor activation
nsu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
nsu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
110584421 (JAK2)
04151 PI3K-Akt signaling pathway
110584421 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
110584421 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
110584421 (JAK2)
09143 Cell growth and death
04217 Necroptosis
110584421 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
110584421 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
110584421 (JAK2)
04659 Th17 cell differentiation
110584421 (JAK2)
04062 Chemokine signaling pathway
110584421 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
110584421 (JAK2)
04917 Prolactin signaling pathway
110584421 (JAK2)
04935 Growth hormone synthesis, secretion and action
110584421 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
110584421 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110584421 (JAK2)
05207 Chemical carcinogenesis - receptor activation
110584421 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
110584421 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
110584421 (JAK2)
05164 Influenza A
110584421 (JAK2)
05168 Herpes simplex virus 1 infection
110584421 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
110584421 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
110584421 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110584421 (JAK2)
05140 Leishmaniasis
110584421 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
110584421 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
110584421 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110584421 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nsu01001
]
110584421 (JAK2)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
110584421 (JAK2)
Protein kinases [BR:
nsu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
110584421 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
110584421
NCBI-ProteinID:
XP_021550128
UniProt:
A0A2Y9HEH0
LinkDB
All DBs
Position
13:complement(6390704..6539858)
Genome browser
AA seq
1130 aa
AA seq
DB search
MACLTMTEMEGTSVSPVQQNGDIPGNANPMKQIDPLLQVYLYHSLEKAEGEYLKFPTGEY
VAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPY
WYCNGSNRTYRHGISRGAEAPLLDDFVMAYLFAQWRHDFLHGWIKIPVTHETQEECLGMA
VLDMMRLAKEKDQTPLDIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQFSH
CKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSRGK
HKESETLTEQDLQLYCDFPDIIDVTIKQASQEGSNESRVVTIHKQDGKNLEIELSSLREA
LSFVSLIDGYYRLTTDAHHYLCKEVAPPMVLENIQSNCHGPILMDFAISKLKKAGNQTGL
YVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNCYQ
METVRSDSIIFQFTKCCPPKLKDKSNLLVFRTNGVSDVPTSPTLQRHNNVNQMVFHKIRN
EDLMFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS
QLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAMH
FLEEKALIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE
CIENPKNLNLAIDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTELAN
LINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPT
QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL
KSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQICK
GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA
PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
KNNGRLPRPDGCPDEIYLIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
NT seq
3393 nt
NT seq
+upstream
nt +downstream
nt
atggcttgccttacaatgacagaaatggaaggaacatccgtatctcctgtacaacagaat
ggtgatattcctggaaatgcgaatcccatgaagcaaatagatccactcctacaggtgtat
ctttatcattctcttgagaaagctgaaggagagtatctgaagtttccaactggggagtat
gttgcagaagaaatttgtgttgctgcttctaaagcttgtggaatcacacctgtgtatcat
agtatgtttgctttaatgagtgaaacagaaaggatttggtatccgcccaaccatgtcttc
catatagatgaatcaaccaggcacaatgtactctacagaataagattttactttccttac
tggtattgtaacggcagcaacagaacctatcggcatgggatatctcgaggtgccgaagct
cctcttcttgacgactttgtcatggcctacctttttgctcagtggcggcatgatttttta
catggatggataaaaatacccgtgacccatgaaacacaggaagaatgtcttggaatggct
gtgttagatatgatgagactagccaaagagaaggatcagaccccactggacatctatagc
tctatcagctacaagacattcttaccaaaatgtgttcgagcaaagatccaagactatcat
attttgacaaggaaacgaataaggtacagatttcgcagatttattgagcaattcagccat
tgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaactcttcag
tctgccttctacacagagcagtttgaagtaaaagaacctggaagaggtccttcaggtgag
gagatttttgcaaccattataataactggaaacggtggaattcagtggtcaagagggaaa
cataaagaaagtgagacactgacagaacaggatttacagttatattgtgactttcctgat
attattgatgttactattaagcaagcaagccaagaaggctcaaatgaaagtagagttgta
actatccataagcaagatggtaaaaatctggaaattgaacttagctcattaagagaagct
ttgtcctttgtgtcattaattgatggctattatagattaactacagatgcacatcattac
ctctgtaaagaagtagcacctccaatggtccttgaaaatatacaaagcaactgtcatggc
ccaattttaatggattttgccatcagtaaactgaagaaagcaggtaatcagactggactc
tatgtacttcgatgcagtcctaaggactttaataagtattttctgacttttgctgtagag
cgagaaaatgtcattgaatataagcactgtttgattacaaaaaatgagaatggagaatac
aacctcagtgggaccaagaagaacttcagtaatcttaaagatcttttgaattgctatcaa
atggaaactgttcgctcagacagtataattttccagtttactaaatgctgtcccccaaag
ttgaaagataaatcaaaccttctagtcttcagaaccaatggcgtttctgatgttccaaca
tcaccaacattacagaggcataataatgtgaaccaaatggtgtttcacaaaatcagaaat
gaagatttgatgtttaatgaaagccttggtcaaggcacttttacaaaaatttttaaaggt
ataagaagagaagtaggagactatggtcaactacatgaaacagaagttctgttaaaagtt
ctggataaagcgcacagaaactattcagagtctttctttgaagcagcaagcatgatgagc
cagctttctcacaagcatctagttttaaattacggagtatgtgtctgtggggaagagaat
attctggttcaagagtttgtaaaatttggatcactagatacatatctgaaaaagaataaa
aattctataaatatattatggaaacttgaagtggctaaacaattggcatgggccatgcat
tttctagaagaaaaagcacttattcatgggaatgtgtgtgccaaaaatattctgcttatc
agagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcctggcatt
agtattacagttttgccaaaggacattcttcaggagagaataccatgggtaccacctgaa
tgcatcgaaaatcctaaaaatctaaatttggcaatagacaagtggagttttggtaccact
ttgtgggaaatctgcagtggaggagataagcctctgagtgctttggattctcaaagaaag
ctacagttttatgaagataggcaccagcttcctgcaccaaagtggacagaattagcaaat
cttattaataattgtatggattatgaaccagattttagaccttctttcagagccatcata
cgagatcttaatagtttgtttactccagattatgaactattaacagagaatgacatgtta
ccaaatatgagaataggtgccctagggttttctggtgcttttgaagaccgagaccctaca
cagtttgaagagagacacttgaaatttctacagcaacttggtaagggtaattttggcagt
gtggagatgtgccggtatgaccctctacaagacaacactggggaggtggtggctgtgaag
aagctccagcacagcactgaggagcacctgagagactttgagagggaaatcgaaatcctt
aaatccctgcagcatgacaacattgtgaagtacaagggagtgtgctacagtgctggtcgg
cgtaatctaagattaattatggaatatttaccatatggaagtttacgagactatctccaa
aaacataaagaacggatagatcataaaaaacttctgcagtatacatctcagatatgcaag
ggcatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaaggaatata
ttggtggaaaacgaaaacagggttaaaattggagattttgggttaaccaaagtcttgcca
caagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctggtatgct
ccagaatcactgacagagagcaagttttctgtggcttcagatgtttggagctttggagtg
gttctgtatgaacttttcacatatattgagaagagtaaaagtcccccagcggaatttatg
cgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagaactccta
aagaataatggaagattaccaagaccagatggatgtccagatgagatttatttgatcatg
acagaatgctggaacaataatgtcaatcaacgcccctcttttagagacctagctcttcga
gttgatcaaataagggacaacatggctggatga
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