Neomonachus schauinslandi (Hawaiian monk seal): 110584977
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Entry
110584977 CDS
T08474
Symbol
PDHB
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit beta, mitochondrial isoform X1
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00010
Glycolysis / Gluconeogenesis
nsu00020
Citrate cycle (TCA cycle)
nsu00620
Pyruvate metabolism
nsu00785
Lipoic acid metabolism
nsu01100
Metabolic pathways
nsu01200
Carbon metabolism
nsu01210
2-Oxocarboxylic acid metabolism
nsu04066
HIF-1 signaling pathway
nsu04922
Glucagon signaling pathway
nsu05230
Central carbon metabolism in cancer
nsu05415
Diabetic cardiomyopathy
Module
nsu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
110584977 (PDHB)
00020 Citrate cycle (TCA cycle)
110584977 (PDHB)
00620 Pyruvate metabolism
110584977 (PDHB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
110584977 (PDHB)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
110584977 (PDHB)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
110584977 (PDHB)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
110584977 (PDHB)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
110584977 (PDHB)
Enzymes [BR:
nsu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
110584977 (PDHB)
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Motif
Pfam:
Transket_pyr
Transketolase_C
Motif
Other DBs
NCBI-GeneID:
110584977
NCBI-ProteinID:
XP_021550839
UniProt:
A0A2Y9HMP6
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All DBs
Position
1:188689761..188695125
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AA seq
359 aa
AA seq
DB search
MAAVSGLMRRPLEQVSGLLRRRFHRTAPAALQVTVREAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSGGHQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
EDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPSEAQSKDFLIPIGKAKIERQGTHITVV
SHSRPVGHCLEAATVLSKEGIECEVINMRTIRPMDIETIEASVMKTNHLITVEGGWPQFG
VGAEVCARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSVPQVKDIIFAIKKTLNI
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atggcggccgtgtctggcctgatgcggagaccccttgaacaggtctccgggctgctgagg
aggcgcttccaccggacggcgccggcggcgctgcaggtgacagttcgtgaggctataaac
caaggtatggatgaggagctggaaagagatgagaaggtatttctgcttggggaagaagtt
gcccagtatgatggggcatataaggttagtcgaggcctgtggaagaaatatggagataag
aggatcatagacactcccatatctgagatgggctttgctggaattgctgtgggtgcagct
atggctgggttgaggcccatttgtgaatttatgaccttcaatttctctatgcaagccatt
gaccaggttataaactcagctgccaagacgtactacatgtcggggggccatcagcctgtg
cccatagtcttcagggggcccaatggtgcctcagcaggcgtggctgcccaacactcacag
tgctttgctgcctggtatgggcactgcccaggcttaaaggtggtcagcccctggaattca
gaggatgcaaaaggacttattaaatcagccattcgggataataatccagtggtggtgcta
gagaatgaactgatgtatggagttccttttgaatttccctcagaagctcagtcaaaagat
tttctgattcccattggaaaagccaaaatagaaaggcaagggacacacataaccgtagtt
tcccattcaagacctgtgggccactgcttagaagctgcgacagtgctatctaaagaggga
attgaatgtgaggtgataaatatgcgaaccatcagaccaatggacattgaaacaatagaa
gccagtgtcatgaagaccaatcatctcataactgtggaaggaggctggccacagtttgga
gtaggagctgaagtttgtgccaggatcatggaaggccctgcattcaatttcctggatgct
cctgcagttcgtgtcactggtgctgatgtccctatgccttatgcaaagattctggaagac
aactctgtacctcaggttaaagacatcatatttgcaataaagaaaacattaaatatttag
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