Neomonachus schauinslandi (Hawaiian monk seal): 110587418
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Entry
110587418 CDS
T08474
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00140
Steroid hormone biosynthesis
nsu01100
Metabolic pathways
nsu05215
Prostate cancer
Module
nsu_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
110587418 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
110587418 (SRD5A2)
Enzymes [BR:
nsu01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
110587418 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
Motif
Other DBs
NCBI-GeneID:
110587418
NCBI-ProteinID:
XP_021553340
UniProt:
A0A2Y9HVF3
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Position
10:complement(25210857..25251075)
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AA seq
254 aa
AA seq
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MSVHCQQSPVLAGSATLAALGALVLYLAKPSGYGKYSESLMPAATRLPARAAWFLQELPS
FAVPAGILARQPRSLFGQPATVLLGLFCAHYFHRTFVYSLLTRGRPFPVAFLVRGFVFCM
GNGLLQAYYLVYCAEYPAEWYTDVRFSLGVFLFILGMGINIHSDYILRQLRKPGEVIYRI
PQGGLFTYVSGANFLGEVIEWTGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFE
DYPKYRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgtccgttcactgccagcagagcccggtgctggcaggcagcgccactttggccgctctg
ggggcactggtcctgtacctcgcgaagccctccggctacgggaagtactcggagagcctg
atgcccgccgccacccgcctgcccgcgcgcgccgcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggatcctcgcccggcagccgcgctcgctcttcggccagcccgcg
acggtgctcctgggcctcttctgcgcacattacttccacaggacctttgtttactcattg
ctcactagagggaggcctttcccagttgcgtttcttgtcagagggtttgtcttctgcatg
ggaaatggactgctccaagcctactatctggtttactgtgctgaataccctgctgagtgg
tacacagacgtacggtttagcctgggtgtcttcttatttattttgggaatgggaatcaac
attcatagtgactatatattgcgccagctcaggaagcctggagaagtcatctataggatt
ccgcaaggtggcttgtttacgtatgtttccggagccaatttccttggtgaggtcattgaa
tggacgggctatgccctggccacttggtccctcccagcacttgcgtttgcgtttttctca
ctttgtttcctggggctgcgagccttccaccaccacaggttctacctcaagatgtttgag
gactatcccaaatatcggaaggccctcattccatttattttttga
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