Neomonachus schauinslandi (Hawaiian monk seal): 110588354
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Entry
110588354 CDS
T08474
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04020
Calcium signaling pathway
nsu04022
cGMP-PKG signaling pathway
nsu04024
cAMP signaling pathway
nsu04148
Efferocytosis
nsu04260
Cardiac muscle contraction
nsu04261
Adrenergic signaling in cardiomyocytes
nsu04380
Osteoclast differentiation
nsu04919
Thyroid hormone signaling pathway
nsu04972
Pancreatic secretion
nsu05010
Alzheimer disease
nsu05017
Spinocerebellar ataxia
nsu05022
Pathways of neurodegeneration - multiple diseases
nsu05410
Hypertrophic cardiomyopathy
nsu05412
Arrhythmogenic right ventricular cardiomyopathy
nsu05414
Dilated cardiomyopathy
nsu05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
110588354 (ATP2A2)
04024 cAMP signaling pathway
110588354 (ATP2A2)
04022 cGMP-PKG signaling pathway
110588354 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
110588354 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
110588354 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
110588354 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
110588354 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
110588354 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
110588354 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
110588354 (ATP2A2)
05017 Spinocerebellar ataxia
110588354 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
110588354 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
110588354 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
110588354 (ATP2A2)
05414 Dilated cardiomyopathy
110588354 (ATP2A2)
05415 Diabetic cardiomyopathy
110588354 (ATP2A2)
Enzymes [BR:
nsu01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
110588354 (ATP2A2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
110588354
NCBI-ProteinID:
XP_021554373
UniProt:
A0A2Y9HRJ5
LinkDB
All DBs
Position
14:complement(84377048..84436018)
Genome browser
AA seq
1042 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDGCSLNEFTITGSTYAPLGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKVERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKVMSVIREWGSGRDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKDDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL
LIMPLVIWVYSTDTNFSDMFWS
NT seq
3129 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcacggggctgagcctggagcaggtcaagaagctcaaggagagatggggttccaacgag
ttaccggctgaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagactta
ctagttagaattttattgctggcagcttgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccctttgtaattttacttatattagtagcc
aatgcaattgtgggtgtatggcaggaaagaaatgctgagaatgcaatcgaagcccttaag
gaatatgagcctgaaatgggcaaagtatatcgacaggacagaaagagtgtccagcggatt
aaagctaaagacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaaatctactactctaagagttgaccagtccattctc
acaggtgagtctgtatctgtcatcaagcacactgaccccgtcccggacccacgggctgtc
aatcaagataaaaagaacatgctcttttctggtacgaacattgctgctggcaaagccatg
ggagtggtggtggcaactggagtgaacacagaaattggcaagatccgggatgaaatggtg
gcaacagagcaggagagaacccccctccagcagaaactagacgagtttggggaacagctt
tccaaagtcatctccctgatttgcattgcagtctggatcataaacattgggcacttcaac
gacccagttcatggaggctcctggatcaggggcgctatttactacttcaaaattgcggtg
gctctggctgtggcagccattcctgaaggtctgcctgctgtcatcactacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgctattgttcgaagcctcccttctgtggaa
acccttggttgtacttccgttatctgctcagacaagactggtacactgacgacgaaccag
atgtctgtgtgcaggatgttcattctggacaaagttgaaggtgatggttgttcccttaat
gagtttaccattaccggatcaacatacgcccctcttggagaagtgcataaagatgataag
ccagtgaaatgtcatcaatatgatggtcttgtggaattggcaacaatttgtgctctttgt
aatgattctgcgttggattacaatgaggcgaagggtgtgtatgaaaaagttggagaagct
acggagactgctcttacttgcctagtagagaagatgaacgtatttgataccgaattgaag
ggtctttctaaagtagagcgagcaaatgcctgcaactcggtcattaagcagttgatgaaa
aaggaatttactctggagttttcacgtgatagaaaatcgatgtcagtttattgtacacca
aacaaaccaagccggacgtcgatgagcaaaatgtttgtgaagggtgctcctgaaggtgtc
attgacaggtgcacccacattcgagttggaagcactaaagttcctatgaccccaggagtc
aaacagaaggtcatgtctgtcattcgggaatggggtagtggccgcgacacactgcggtgc
ctggctctggccactcacgacaacccactgagaagagaagaaatgaaccttgaggactct
gccaactttattaaatatgagaccaatctgactttcgttggctgcgtgggcatgctggac
cctccaagaattgaagtggcctcttctgtgaagctgtgccggcaggcaggcatccgggtt
atcatgatcactggggacaacaagggcactgctgtggccatctgtcggcgtattggcatc
ttcgggcaggacgaggatgtgacgtcgaaagcttttacgggtcgggagtttgatgagctc
agtccttcagcccagagagatgcctgtttgaatgcccgatgtttcgctcgagttgaacct
tcccacaagtcaaaaattgtagaatttcttcagtcttttgatgagataacggctatgact
ggggacggtgtgaatgatgctcctgccctgaagaaatcagagatcggcattgccatgggc
tctggcactgcagtggctaaaacggcgtctgagatggtcctggctgacgacaacttctcc
accattgtggctgcggtggaggaggggcgggccatctacaacaatatgaagcagtttatc
cgctacctcatctcgtcgaatgtgggggaagttgtctgtatcttcctgacagcagccctt
ggatttcctgaggctttaattcctgtccagctgctctgggtcaatctggtgacagacggt
ctgcccgccactgccctggggttcaaccctcccgatctggacatcatgaataaaccaccc
cggaacccgaaggaacctctgatcagcggatggctctttttccgttatctggccattggc
tgttacgttggcgctgctaccgtgggtgctgctgcgtggtggttcattgctgccgacgga
ggtccgagagtgaccttctaccagctgagccacttcctacagtgtaaagatgacaacccg
gactttgaaggagtggattgtgcaatctttgagtccccatacccgatgacaatggcgctg
tctgttctagtaaccatagagatgtgtaacgccctcaacagcttgtctgaaaaccagtcc
ctgctgaggatgccgccctgggagaacatctggctcgtgggctccatttgcctgtccatg
tcgctccacttcctcatcctctacgtggaacctttgccacttattttccagatcacaccg
ctgaatttgacccagtggctgatggtgctgaaaatctccttgcctgtgattctaatggac
gagacactcaagttcgtggcccgcaactacctggaacctggtaaagagtgtgtgcagcct
gccaccaaatcctgctcgttctcggcatgcaccgatgggatttcctggccgtttgtgctg
ctcataatgcccctggtgatctgggtctatagcacagacactaactttagtgatatgttc
tggtcttga
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