Neomonachus schauinslandi (Hawaiian monk seal): 110590246
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Entry
110590246 CDS
T08474
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X4
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00280
Valine, leucine and isoleucine degradation
nsu00640
Propanoate metabolism
nsu00785
Lipoic acid metabolism
nsu01100
Metabolic pathways
nsu01210
2-Oxocarboxylic acid metabolism
Module
nsu_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
110590246 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
110590246 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
110590246 (BCKDHA)
Enzymes [BR:
nsu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
110590246 (BCKDHA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
DUF6409
Motif
Other DBs
NCBI-GeneID:
110590246
NCBI-ProteinID:
XP_021556682
UniProt:
A0A2Y9HYB3
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Position
16:complement(12025227..12045083)
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AA seq
392 aa
AA seq
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MAVAAAAARVWGSSRGLGQAGLLLLRRPGARGLARSLPQRQVQQHFPSLDDKPQFPGASA
EFVDKLEFIQPNVISGIPVYRVMDRQGQIINPSEDPHLPQEKVLKFYKSMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAAVGAAYAAKRANANRVVI
CYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGI
MSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNY
WDKQDHPISRLRHYLQSRGWWDEEQEKAWRKQSRKKVMEAFEQAERKPKPSPSLLFSDVY
QEMPAQLRKQQEALARHLQTYGEHYPLDHFEK
NT seq
1179 nt
NT seq
+upstream
nt +downstream
nt
atggcggtggcggctgcagcagcgagggtctggggctcaagtcgaggcttgggccaggct
ggcctcctgctcctgcggcggcctggggctcgggggctggctagatctctcccccagaga
caggtgcagcagcacttcccgtccctggatgacaagccccagttcccaggggcctcggcg
gagtttgtagacaagctagaattcatccagcccaatgtcatctctgggatccccgtctac
cgtgtcatggatcgccagggccagatcatcaaccccagcgaggatccccacctgccccag
gagaaggtgctcaagttttacaagagcatgactctgctcaacaccatggaccgcatcctc
tatgagtcccagcgacagggccggatctccttctacatgaccaactacggcgaggagggg
acgcacgtggggagcgcagcagcgctggacaacacggacctggtgttcggccagtaccgg
gaggcagcggtgggggcggcctacgcggccaagcgggccaacgccaacagggtggtcatc
tgctacttcggggagggagcggccagcgagggggacgcacacgccggcttcaacttcgcc
gccaccctcgagtgccccatcatcttcttctgccggaacaacggctatgccatctccacg
cccacctcggagcagtaccgcggggacggcatcgctgcccgaggccccggctatggcatc
atgtccatccgcgtggatggcaacgacgtgtttgctgtgtacaacgccaccaaggaggcc
cggcggcgcgctgtggcggagaaccagcccttcctcatcgaggccatgacctacaggatc
ggccaccacagcactagtgatgacagctcagcctaccgctcggtggacgaggtcaattac
tgggacaagcaggaccaccccatctcccggctgcgccactacctgcagagccggggctgg
tgggacgaggagcaggagaaggcctggaggaagcagtcccgcaagaaggtgatggaggcc
tttgagcaggcagagcggaagccaaagcccagccccagcctgctcttctcagacgtgtac
caggagatgcccgcccagctccgcaagcagcaggaggccctggcccggcacctccagacc
tacggggagcactaccccctggaccactttgagaagtga
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