Neomonachus schauinslandi (Hawaiian monk seal): 110590530
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Entry
110590530 CDS
T08474
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu01521
EGFR tyrosine kinase inhibitor resistance
nsu01522
Endocrine resistance
nsu04010
MAPK signaling pathway
nsu04012
ErbB signaling pathway
nsu04014
Ras signaling pathway
nsu04062
Chemokine signaling pathway
nsu04068
FoxO signaling pathway
nsu04072
Phospholipase D signaling pathway
nsu04150
mTOR signaling pathway
nsu04151
PI3K-Akt signaling pathway
nsu04510
Focal adhesion
nsu04540
Gap junction
nsu04630
JAK-STAT signaling pathway
nsu04650
Natural killer cell mediated cytotoxicity
nsu04660
T cell receptor signaling pathway
nsu04662
B cell receptor signaling pathway
nsu04664
Fc epsilon RI signaling pathway
nsu04714
Thermogenesis
nsu04722
Neurotrophin signaling pathway
nsu04810
Regulation of actin cytoskeleton
nsu04910
Insulin signaling pathway
nsu04912
GnRH signaling pathway
nsu04915
Estrogen signaling pathway
nsu04917
Prolactin signaling pathway
nsu04926
Relaxin signaling pathway
nsu04935
Growth hormone synthesis, secretion and action
nsu05034
Alcoholism
nsu05160
Hepatitis C
nsu05161
Hepatitis B
nsu05163
Human cytomegalovirus infection
nsu05165
Human papillomavirus infection
nsu05200
Pathways in cancer
nsu05205
Proteoglycans in cancer
nsu05206
MicroRNAs in cancer
nsu05207
Chemical carcinogenesis - receptor activation
nsu05208
Chemical carcinogenesis - reactive oxygen species
nsu05210
Colorectal cancer
nsu05211
Renal cell carcinoma
nsu05213
Endometrial cancer
nsu05214
Glioma
nsu05215
Prostate cancer
nsu05220
Chronic myeloid leukemia
nsu05221
Acute myeloid leukemia
nsu05223
Non-small cell lung cancer
nsu05224
Breast cancer
nsu05225
Hepatocellular carcinoma
nsu05226
Gastric cancer
nsu05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110590530 (SOS2)
04012 ErbB signaling pathway
110590530 (SOS2)
04014 Ras signaling pathway
110590530 (SOS2)
04630 JAK-STAT signaling pathway
110590530 (SOS2)
04068 FoxO signaling pathway
110590530 (SOS2)
04072 Phospholipase D signaling pathway
110590530 (SOS2)
04151 PI3K-Akt signaling pathway
110590530 (SOS2)
04150 mTOR signaling pathway
110590530 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
110590530 (SOS2)
04540 Gap junction
110590530 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
110590530 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
110590530 (SOS2)
04660 T cell receptor signaling pathway
110590530 (SOS2)
04662 B cell receptor signaling pathway
110590530 (SOS2)
04664 Fc epsilon RI signaling pathway
110590530 (SOS2)
04062 Chemokine signaling pathway
110590530 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
110590530 (SOS2)
04912 GnRH signaling pathway
110590530 (SOS2)
04915 Estrogen signaling pathway
110590530 (SOS2)
04917 Prolactin signaling pathway
110590530 (SOS2)
04926 Relaxin signaling pathway
110590530 (SOS2)
04935 Growth hormone synthesis, secretion and action
110590530 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
110590530 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
110590530 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110590530 (SOS2)
05206 MicroRNAs in cancer
110590530 (SOS2)
05205 Proteoglycans in cancer
110590530 (SOS2)
05207 Chemical carcinogenesis - receptor activation
110590530 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
110590530 (SOS2)
05231 Choline metabolism in cancer
110590530 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
110590530 (SOS2)
05225 Hepatocellular carcinoma
110590530 (SOS2)
05226 Gastric cancer
110590530 (SOS2)
05214 Glioma
110590530 (SOS2)
05221 Acute myeloid leukemia
110590530 (SOS2)
05220 Chronic myeloid leukemia
110590530 (SOS2)
05211 Renal cell carcinoma
110590530 (SOS2)
05215 Prostate cancer
110590530 (SOS2)
05213 Endometrial cancer
110590530 (SOS2)
05224 Breast cancer
110590530 (SOS2)
05223 Non-small cell lung cancer
110590530 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
110590530 (SOS2)
05160 Hepatitis C
110590530 (SOS2)
05163 Human cytomegalovirus infection
110590530 (SOS2)
05165 Human papillomavirus infection
110590530 (SOS2)
09165 Substance dependence
05034 Alcoholism
110590530 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110590530 (SOS2)
01522 Endocrine resistance
110590530 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
IQ_SEC7_PH
PH_19
PH_10
Motif
Other DBs
NCBI-GeneID:
110590530
NCBI-ProteinID:
XP_021557027
UniProt:
A0A2Y9HZ86
LinkDB
All DBs
Position
9:47669746..47750637
Genome browser
AA seq
1338 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
DRIFSNISDIHELTLKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSIIFAARSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVIKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GILFKGKAMKKWVESIAKIIRRKKQAQANGISHNITFESPPPPIEWHISRAGQFETFDLM
TLHPIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEK
CIVEAENFEERVAILSRIIEILQVFQDLNNFSGVLEIVSAVNSVSVYRLDHTFEALQERK
RRILDEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLIN
FSKRRKVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGSASEKEFTDYLFNKSLEIE
PRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKMSFSRIAETD
LESTVSAPTSPNTPSTPPVSASSDLSVFLDVDLNNSCGSNSIFAPVLLPHSKSFFSSCGS
LHKLSEEQLLIPPPLPPRKKFDHDASNSKGNTKSDDDPPAIPPRQPPPPKVKPRVPAPTG
AFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVST
CPNSPNTPPSTPSPRVPRRCYMLSSSHNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKREL
SHPPSYRLPLLENAETPQ
NT seq
4017 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccgtacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgctggtctcggccctgcggaaggttcaggagcaagtacatcccaatctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggctcaaccaaggactgttcaagatgtggaggaacgtgttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacaatctgccatagaaaaacgaaaacgaaga
aatcctctcttactccctgtggacaaaatccatccttcattgaaggaagttttagggtac
aaagtggactatcatgtatccctgtatattgtggctgtactagagtatatctcagctgat
attttgaagttggctggtaattatgtttttaatatccgacattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgaccaggatgac
ataggtttggtttctctctgtgaagatgaacccagttcttcaggtgaattaaactactat
gaccttgtcagaactgaaattgcagaagaaaggcagtatctacgggaactaaatatgatc
ataaaagtgtttcgagaagcctttctttctgacagaaagctgtttaaaccttctgatatt
gacaggattttcagtaacatttcagatatacatgaattaactctgaaacttttaggttta
attgaagacacagttgaaatgactgatgaaagcagtcctcatccgttagctggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacgttatcacaggacatt
ctttctccaaaatttaatgaacatttcagtaagttgatggccagacctgcggtggcgcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgcctt
atgctggtgcctgtttatcattgttggcactattttgaattattaaagcaattgaaagca
tgtagtgaagagcaggaagacagagaatgtttgaaccaagctattactgctcttatgaat
ctccaaggtagtatggaccgaatttacaagcagtattcacctagacgccgacctggggat
cctgtttgccctttttataatcgtcagttaagaagcaagcatctggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat
gaattcattatggaaggtccattgacacgaattggtgctaaacatgaacgacatattttt
ctctttgatggcttaatgatcagctgtaagcccaatcatagtcagtcacgccttccaggt
tatagtagtgcagaatacagattaaaagaaaaatttgtcatgaggaaaatacaaatatgt
gataaagaagatacttgtgagtgcaaacatgcttttgagttggtatccaaagatgaaaat
agcataatatttgctgctaggtctgctgaagagaaaaataattggatggctgcacttatt
tctcttcactatcgtagtacactagatcgaatgctagattcagtgttattgaaagaagaa
aatgagcaaccattgagattaccaagtcctgaagtgtatcgttttgtgataaaagactct
gaggaaaacattgtttttgaagacaacctgcaaagtagaagtggaatccccattattaaa
ggaggaactgtagtgaaattaattgaaaggttaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacataccgttcattttgtaaaccacaggaattgctaagc
ttactgattgaacgatttgaaattccagagccagaacctactgaagcagataaattggcc
gtagagaaaggcgaacagccaatcagtgcagaccttaaaaggtttcgcaaggaatatgtc
caaccagtacaacttaggattttaaatgtgtttcggcactgggttgaacaccatttttat
gactttgaaagagatttggagttgcttgaaagactagaatccttcatttcaagtgtaaga
ggtatattatttaaagggaaagctatgaagaaatgggtagagtcaattgctaagatcatc
aggagaaagaaacaagctcaggcaaatggaataagccataatattacctttgaaagtcca
cctccgccaattgaatggcatatcagcagagcgggacagtttgaaacatttgatctcatg
acacttcatccaatagaaattgcacgtcagctgacacttttggaatctgatctctacagg
aaagtccaaccttctgaactagtagggagtgtatggaccaaagaagataaagaaataaat
tctccaaatttattaaaaatgattcgccataccacaaatctcaccctatggtttgaaaag
tgcattgtggaagcagaaaattttgaggagcgggtggcaatactaagtagaattatagaa
attctgcaagtttttcaagatttgaataatttcagtggtgtattggagatagtcagtgcg
gtaaattcagtgtcggtatacagactagaccatacttttgaggcgttgcaggaaagaaaa
aggagaattttggatgaagctgtggaattaagtcaagatcactttaaaaaatacctagta
aaacttaagtcaatcaatccaccttgtgtgcctttttttggaatatatttaacaaatatt
ctgaaaactgaagaagggaataatgattttttaaaaaagaaagggaaagatttaatcaat
ttcagtaagaggaggaaagtagctgaaattacgggagaaattcagcagtatcagaatcaa
ccttactgtttacggatagaaccagaaatgaggaggttctttgaaaaccttaaccccatg
ggaagtgcttctgaaaaggagtttacagattatttgttcaacaagtcactagaaattgaa
ccccgaaactgcaaacagccacctcgatttcctaggaaatcaactttctctttaaaatct
cctggaatacggcctaatacaggccgacatggctctacctcaggcactttacgaggtcat
ccaacgccattagaaagagaaccatgtaaaatgagctttagtcggattgctgaaactgat
cttgaatcaactgtgtcagcaccaacctctccaaatacaccatctactccaccagtatct
gcttcttcagaccttagtgtgtttttagatgtggatctcaacaattcctgtggcagcaat
agcatctttgctccagtcctcttgccacactcaaagtctttcttcagttcatgtggcagt
ttacacaaactaagtgaagagcagctgctgattcctcctccgcttcctcctcgaaagaag
tttgatcatgacgcttcaaattccaagggaaatacgaaatctgatgatgacccccctgct
attccaccaagacaacctcctcctccaaaggtaaaacccagagttcctgctcctactggt
gcatttgatgggcctctgcatagtccacctccaccaccgccaagagatcctcttcctgat
acccctccaccagttccccttcggcctccagaacactttataaactgtccatttaatctt
cagccacctccactaggacatcttcacagagatccagactggttcagagacgttagtacc
tgtccaaattcgccaaatactcctcctagcacaccctctccgagagtaccacgtcgatgc
tacatgctcagttctagtcacaacaaccttgctcatcctcaagctccccctgttccacca
aggcagaattcaagccctcacctaccaaaactgccaccaaagacttacaaacgggagctt
tcgcaccctccgtcatacagactgcctttgctagaaaatgcggaaactcctcaatga
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