Neomonachus schauinslandi (Hawaiian monk seal): 110590753
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Entry
110590753 CDS
T08474
Symbol
KDR
Name
(RefSeq) vascular endothelial growth factor receptor 2
KO
K05098
kinase insert domain protein receptor [EC:
2.7.10.1
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu01521
EGFR tyrosine kinase inhibitor resistance
nsu04010
MAPK signaling pathway
nsu04014
Ras signaling pathway
nsu04015
Rap1 signaling pathway
nsu04020
Calcium signaling pathway
nsu04151
PI3K-Akt signaling pathway
nsu04370
VEGF signaling pathway
nsu04510
Focal adhesion
nsu05205
Proteoglycans in cancer
nsu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110590753 (KDR)
04014 Ras signaling pathway
110590753 (KDR)
04015 Rap1 signaling pathway
110590753 (KDR)
04370 VEGF signaling pathway
110590753 (KDR)
04020 Calcium signaling pathway
110590753 (KDR)
04151 PI3K-Akt signaling pathway
110590753 (KDR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
110590753 (KDR)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
110590753 (KDR)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
110590753 (KDR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110590753 (KDR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nsu01001
]
110590753 (KDR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
nsu04090
]
110590753 (KDR)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
110590753 (KDR)
Protein kinases [BR:
nsu01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
110590753 (KDR)
CD molecules [BR:
nsu04090
]
Proteins
110590753 (KDR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
VEGFR1-3_N_Ig-like
Ig_3
I-set
Pkinase
VEGFR-1-like_Ig-like
Ig_2
ig
Ig_VEGFR-1-like_5th
V-set
VEGFR-2_TMD
C2-set_2
Ig_4
V-set_CD47
Haspin_kinase
BppU_N
Motif
Other DBs
NCBI-GeneID:
110590753
NCBI-ProteinID:
XP_021557252
UniProt:
A0A2Y9HZU6
LinkDB
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Position
2:160274028..160317510
Genome browser
AA seq
1355 aa
AA seq
DB search
MESKALLAIALWLCVETRAASVGLPSVSLDPPRLSIQKDILTIMANTTLQITCRGQRDLD
WLWPNNQSGSEKRVEVTECRDSLFCKMLMIPKVIGNDTGAYKCFYRDTEMASVIYVYVRD
YRSPFIASVSDQHEVVYITEKKNKTVVIPCLGSVSNLNVSLCARYPEKRFVPDGNRISWD
SKKGFTIPSYMISYAGMVFCEAKINDESYQSVMYIVVVVGYKIYDVVVSPPLEVELSVGE
RLVLNCTARTELNVGIDFNWEYPSLKHRHKKLVIRDLKTQSGSEMKKFLSTLTIDGVTRS
DQGQYICEASSGMMTMKSNTSVRVHEKPFVAFDSSMESLVEATVGDHVKVPVKYLAYPTP
EIKWYKNGRPIESNHTIKGEKELIIMEVSEKDTGNYTVVLTNPMSKEKQSHVVSLVVNVP
PQIGEKSLISLVDSYQYGTTQMLTCTVYSVPPPHHIRWYWQLEECAYKPAQAVLMTNPYT
CKEWRNVDDFQGGNKIEVNKNQFAIIEGKNKTVSTLVIQAANVSALYKCEAINKVGRGER
VISFHVTRGPKITLQPHTQPTEQESVSLWCSADRTMFEDLTWYKFSPQALPIRSGELPTP
VCKNLDALWKMNSTKISNGTSDILIMELQNASLQDQGDYVCFAQDRKTKKKHCVVRQLTV
LERVAPMITGNLENQTTSIGETIEVSCTTSGNPAPQVTWFKDNETLVEDSGIVLKDGNRN
LTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIVEGAQEKTNLEVIILVGTAVIAMFFWLL
LVIVLRTVKRASGGELKTGYLSIVMDPDELPLDEHCERLPYDASKWEFPRDRLKLGKPLG
RGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNL
LGACTKPGGPLMVIVEFCKFGNLSTYLRNKRNEFVPYKTKGARFRQGKEYVGEITMDPKR
RLDSITSSQSSASSGFVEEKSLSDVEEEEVSEDLYKNFLTLEHLICYSFQVAKGMEFLAS
RKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRV
YTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYATPEIYQTMLD
CWHGEPNQRPTFSELVEHLGNLLQANAQQDGKDYIVLPISETLSMEEDSGLSLPTSPVSC
MEEEEVCDPKFHYDNTAGISQYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDNQTDSG
MVLASEELKTLEDRTKLAPSFSGLMPSKSKESVASEGSNQTSGYQSGYHSDDTDTTVYSS
EEAELLKLVEIGPQVGSASQMLQPDSGPTLSSPPV
NT seq
4068 nt
NT seq
+upstream
nt +downstream
nt
atggagagcaaggcgctgctggccatcgctctgtggctctgcgtggagaccagggctgcc
tcagtgggtttgcctagtgtttcccttgatccacccagactcagcatacaaaaagacata
cttacaattatggctaatacaactcttcagattacttgcaggggacagagggacttggac
tggctctggcccaataatcagagtggctctgagaaaagagtggaggtgaccgagtgcagg
gacagcctcttctgtaagatgctcatgattccaaaagtgattggaaacgatactggagcc
tacaagtgcttctaccgggacactgaaatggcctcggtcatttatgtgtacgttcgagat
tacagatctccatttattgcttctgttagtgaccaacatgaagttgtgtacatcactgag
aagaaaaacaaaactgtggtgattccatgtcttggatccgtttccaacctcaatgtgtca
ctttgtgcaaggtatccagaaaagaggtttgtccctgatggtaacagaatttcctgggac
agtaagaaaggcttcactatccccagctacatgatcagctatgctggcatggtcttctgt
gaagcaaaaattaatgatgaaagttaccagtctgttatgtacatagttgtggttgtaggg
tacaagatttatgatgtggttgtcagcccccctctcgaagttgagctgtctgttggagag
aggcttgtcttaaattgtacagcaaggactgaactaaatgtggggattgacttcaactgg
gaatatccttctttgaagcatcggcataaaaaacttgttatccgggacctaaaaacccag
tctgggagtgagatgaagaaatttttgagcaccttgactatagatggtgtaacccggagt
gaccaagggcagtatatctgtgaggcttccagtgggatgatgaccatgaagagcaacaca
tcagtcagggtccatgaaaaaccttttgttgcttttgatagtagcatggaatctttggtg
gaagccacagtgggagaccatgttaaagtccccgtgaagtaccttgcttaccctacccct
gaaataaaatggtataaaaatggaagacccattgagtccaatcacacaataaaaggggag
aaggaactgattattatggaagtgagtgaaaaagatacaggaaattatactgttgtcctc
accaatcccatgtcaaaggagaaacagagccacgtggtatctctggttgtgaatgtccca
ccccagatcggtgagaagtccctgatctctctggtggattcttaccagtacggcaccaca
cagatgctgacgtgcacggtctactccgtcccgcccccgcatcacattcgctggtattgg
cagctggaggagtgcgcctacaagcccgcccaagctgtcttaatgacaaacccatatact
tgtaaagaatggagaaatgtggatgacttccaggggggaaataaaattgaagtcaacaaa
aatcaatttgccataattgaaggaaaaaacaaaactgtaagtacccttgttatccaagca
gcaaatgtgtcagctttgtacaaatgtgaagccatcaacaaagttgggagaggagagagg
gtgatctccttccatgtgaccaggggccctaaaatcactttgcaacctcacacccagcca
actgaacaggagagcgtgtctttgtggtgctctgcagacagaactatgtttgaggacctc
acgtggtacaagtttagcccacaggctctgccaatccgttcgggagagttgcccacacct
gtttgcaagaacttggatgctctttggaaaatgaactccaccaagatctctaatggcaca
agtgacattttgatcatggagctccagaatgcatccttgcaggaccaaggagactatgtg
tgctttgcccaggacaggaagacaaagaaaaaacattgtgtggtcagacagctcacagtt
ttagagcgtgtggcacccatgatcactggaaacctggagaatcagactacaagcattggt
gaaaccattgaagtttcatgcaccacgtctgggaatcccgctccacaagttacgtggttt
aaagacaatgagacacttgtagaagactcaggtattgtactgaaagatgggaaccggaac
ctaaccatccgcagagtgaggaaggaggatgaaggcctctatacctgccaggcatgcagt
gttcttggttgtgcaaaagtggaggcatttttcatagtagaaggtgcccaggagaagacg
aacctggaagtcattattctagtaggcacggcagtgattgccatgttcttctggttatta
cttgtcatcgttctacggaccgttaagcgggccagtggaggggaactgaagacaggctac
ttgtccatcgtcatggatccagatgaactccccttggatgagcactgtgaacgcctgcct
tatgatgctagcaaatgggagttccccagagaccggctgaaactaggtaagcctctcggc
cgtggtgcctttggccaagtgattgaagcggatgcctttggaatcgacaagacagcaact
tgcaggacggtggccgtcaaaatgttaaaagaaggagcaacacacagtgaacaccgagcc
ctcatgtctgaactcaagatcctcattcatattggccaccatctcaatgtggtcaatctt
ctaggtgcctgtaccaagccaggagggccactcatggtgattgtggagttttgcaagttt
ggaaacctgtcaacttacttaaggaacaagagaaatgaatttgtcccctacaagaccaaa
ggagcacgattccgtcaagggaaagaatacgttggggaaatcactatggatccgaaacgc
cgcttggacagtatcaccagtagtcagagctcagccagctctggatttgttgaggagaag
tccctcagtgatgtggaggaagaggaagtttctgaagatctgtacaagaacttcctgacc
ttggagcatctcatctgttacagcttccaagtggctaagggcatggagtttttggcatca
cggaagtgtatccacagggacctggccgcacgcaacatcctcttgtcggagaagaacgtg
gttaaaatctgtgactttggcttggcccgggatatttataaagacccagattatgtcaga
aaaggagatgctcgcctccctttgaaatggatggccccagaaacaatttttgacagagtg
tacacaattcagagtgatgtgtggtctttcggtgtcttgctctgggaaatattttcctta
ggtgcttctccatatcctggagtaaagattgatgaggaattctgtaggcgattaaaagaa
ggcactagaatgagggcccctgattatgccacaccagaaatataccagaccatgcttgac
tgctggcacggggagcccaatcagagacccacgttttcagagctggtggaacacttggga
aatctgttacaagctaatgctcagcaggatggcaaagactacattgttctcccgatatca
gagactttgagcatggaagaggattctggactctccctgcctacctcacctgtttcctgt
atggaggaagaggaagtgtgtgaccccaaattccattatgacaacacagcaggaatcagc
cagtatctgcagaacagtaagcgaaaaagccggcccgtgagtgtaaaaacatttgaagat
atcccgttggaagaaccagaagtaaaagtaatcccagatgacaaccagacggacagtggt
atggtccttgcatcagaagagctgaaaaccttggaagacagaaccaaattagcgccatct
tttagtggactgatgcccagcaaaagcaaggagtctgtggcatccgaaggctctaaccaa
acgagtggctaccagtctgggtatcactcggatgacacggacacgactgtgtactccagc
gaggaggccgaactgttaaagctggtggagattggaccgcaagttggcagtgcatcccag
atgctccagcctgactctgggcccacattgagctctcctcctgtttaa
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