Neomonachus schauinslandi (Hawaiian monk seal): 110590873
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Entry
110590873 CDS
T08474
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu01521
EGFR tyrosine kinase inhibitor resistance
nsu04010
MAPK signaling pathway
nsu04014
Ras signaling pathway
nsu04015
Rap1 signaling pathway
nsu04020
Calcium signaling pathway
nsu04072
Phospholipase D signaling pathway
nsu04144
Endocytosis
nsu04151
PI3K-Akt signaling pathway
nsu04510
Focal adhesion
nsu04540
Gap junction
nsu04630
JAK-STAT signaling pathway
nsu04810
Regulation of actin cytoskeleton
nsu05163
Human cytomegalovirus infection
nsu05200
Pathways in cancer
nsu05206
MicroRNAs in cancer
nsu05214
Glioma
nsu05215
Prostate cancer
nsu05218
Melanoma
nsu05230
Central carbon metabolism in cancer
nsu05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110590873 (PDGFRA)
04014 Ras signaling pathway
110590873 (PDGFRA)
04015 Rap1 signaling pathway
110590873 (PDGFRA)
04630 JAK-STAT signaling pathway
110590873 (PDGFRA)
04020 Calcium signaling pathway
110590873 (PDGFRA)
04072 Phospholipase D signaling pathway
110590873 (PDGFRA)
04151 PI3K-Akt signaling pathway
110590873 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
110590873 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
110590873 (PDGFRA)
04540 Gap junction
110590873 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
110590873 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110590873 (PDGFRA)
05206 MicroRNAs in cancer
110590873 (PDGFRA)
05230 Central carbon metabolism in cancer
110590873 (PDGFRA)
05231 Choline metabolism in cancer
110590873 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
110590873 (PDGFRA)
05218 Melanoma
110590873 (PDGFRA)
05215 Prostate cancer
110590873 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
110590873 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110590873 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nsu01001
]
110590873 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
nsu04090
]
110590873 (PDGFRA)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
110590873 (PDGFRA)
Protein kinases [BR:
nsu01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
110590873 (PDGFRA)
CD molecules [BR:
nsu04090
]
Proteins
110590873 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
Herpes_gE
DUF3475
Kinase-like
Motif
Other DBs
NCBI-GeneID:
110590873
NCBI-ProteinID:
XP_021557374
UniProt:
A0A2Y9I564
LinkDB
All DBs
Position
2:complement(160977477..161009218)
Genome browser
AA seq
1089 aa
AA seq
DB search
MGTSLLALLILGCLLTGPSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP
MSEEENPNVEIRNEENNSGLFVTVLEVVNASAAHTGLYTCYYNHTQTEETEIEGRHIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLRSSDGVVHASYDSRQGFNG
TFSVGPYVCEATIRGKTFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLRVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFIEIKPNFNPLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDIERIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWAVLANNISNIITEVHPRD
RSTVEGRVTFTRVEETIAVRCLAKNLLGAESRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKEELDIFGLNPADDSTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVEHLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGSLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccttctggccctcctgatcttaggctgtctcctcacagggcccagccta
atcctctgccagctttcattaccgtctatcctccctaacgaaaatgaaaaggtcgtgcag
ctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaaatcagaaatgaggagaataacagtggcctt
tttgtgaccgtgctggaggtggtcaacgcgtcggcggcgcacacaggcttgtacacttgc
tattacaaccacactcagacggaggaaacggagatcgaaggcaggcacatctacatctac
gtgccagacccggatgtagcctttgtacctctaggaatgacagattatttagtcatcgtg
gaggatgatgattctgccatcataccttgtcgcacaactgaccccgagactccggtgacc
ttgcgcagcagtgacggggtggtgcacgcctcctatgacagcagacagggctttaatggg
accttcagcgtcgggccctatgtctgcgaagccaccatcagagggaagacgttccagacc
atcccgtttaatgtttatgctttaaaagcaacatcagaacttgatctagaaatggaagct
cttaaaactgtgtataagtcaggggagacgattgtggtcacctgcgccgtctttaacaat
gaggtggttgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcaccatg
ctggaggaaatcaaggtcccgtccatcaaactggtgtacactctgagggtccccgaggcc
acggtgaaagatagtggagattatgaatgtgctgcccgccaggccaccaaggaggtcaaa
gagatgaagaaagtcaccatttctgtccatgagaaagggttcattgaaatcaaacccaac
ttcaacccactggaagctgtcgacctacatgaagtcaaacattttgtggtggacgtgcag
gcctacccccctcccaggatatcctggctgaaggacaacctgactctgattgaaaatctc
acagagatcaccacggacatagaaaggattcaggaaataaggtatcggagcaaattaaag
ctgatccgcgctaaggaggaagacagcggccattacacgatcgtcgttcaaaatgaagac
gacgtgaagagctatactttcgagctcttaactcaagttccctcgtctattctggacttg
gttgatgaccaccatggctctacagggggacagactgtgagatgcaccgctgaagggacg
cctcttcctgatatcgagtggatgatctgcaaggatattaagaagtgtaataatgaaact
tcatgggctgttttggccaacaatatctcaaacatcatcacggaggtccacccccgagac
aggagtactgtggagggccgagtgacattcaccagggtggaggagaccatcgctgttcga
tgtctggccaagaatctccttggggccgagagccgagagctgaagctggtggctcccacg
ctgcgttctgaactcaccgtcgccgctgcggtcctcgtgctgttggtgattgtgatcatc
tcacttattgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgttggagg
gtcattgaatccatcagccctgacggacatgaatatatttacgtggacccgatgcagctg
ccttatgactcaagatgggagtttccaagggatggactcgtgcttggtcgtatcctggga
tctggtgcgtttgggaaagtggttgaaggaactgcctatgggttaagccgctcccagcct
gtcatgaaagtagcagtgaagatgctaaaacccacagccagatccagcgagaaacaagct
ctcatgtcggaactgaagataatgactcacctggggccgcatttaaacattgtgaacttg
ctgggagcctgcaccaagtcaggccctatttacatcatcaccgagtactgcttctatggg
gatttggtcaactatttgcataagaatagggatagcttcctgagccgccacccggagaaa
ccaaaggaagagctggacattttcggattgaaccctgccgatgatagcacacggagttat
gttattttatcttttgaaaacaatggtgactacatggacatgaagcaagctgacaccacc
cagtatgtccccatgctggaaaggaaagaggtttctaaatactcggacatccagagatcg
ctgtatgaccgcccagcctcgtataagaagaagtctatgttagactcagaagtcaaaaac
ctcctttcggacgataactcagaaggccttaccttgttggacttgttgagctttacctat
caagttgctcgaggaatggaatttttggcttcaaaaaattgtgtccaccgggacctggct
gctcgaaacgtcctcctggcgcaggggaaaatcgtgaagatctgtgacttcggcctggcc
agagacatcatgcatgattcaaactacgtgtccaaaggcagtacctttctccccgtgaag
tggatggcccctgagagcatcttcgacaacctctacaccacgctgagtgacgtctggtcc
tacggcattctgctctgggagatcttttcccttggcggcacaccctaccccggcatgatg
gtggattctactttctacaataagatcaagagtgggtaccggatggccaagcctgaccat
gccaccagtgaagtctacgagatcatggtgaagtgctggcacagcgagccggagaagaga
ccctccttctaccacctgagtgagattgtggagcatctgctgcctggacagtataagaag
agttatgaaaagattcacctggacttcctgaagagcgaccaccccgccgtggcgcgcatg
cgcgtggactcggacaatgcctacattggcgtcacctacaaaaacgaggaagacaagctg
aaggactgggagggcagcctggacgagcagaggctgagcgcggacagcggctacatcatc
cccctgcccgacatcgaccctgttcctgaggaggaagacctgggcaagaggaacagacac
agctcgcagacctcagaagagagcgctatcgagacaggttccagcagctctactttcatc
aagagagaggatgaaaccatcgaggacatcgacatgatggacgacattggcatagactcc
tcagacctggtagaggacagcttcctgtga
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