Neomonachus schauinslandi (Hawaiian monk seal): 110591286
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Entry
110591286 CDS
T08474
Symbol
PDE4D
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00230
Purine metabolism
nsu01100
Metabolic pathways
nsu04024
cAMP signaling pathway
nsu04928
Parathyroid hormone synthesis, secretion and action
nsu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
110591286 (PDE4D)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
110591286 (PDE4D)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
110591286 (PDE4D)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
110591286 (PDE4D)
Enzymes [BR:
nsu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
110591286 (PDE4D)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
110591286
NCBI-ProteinID:
XP_021557836
UniProt:
A0A2Y9I222
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Position
7:complement(41422379..42293993)
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AA seq
811 aa
AA seq
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MEAEGSSVPAQAGSDEGSDGAGGATLKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPP
PPPSPQPQPQPQCPLQPPPPPPLPPPPPLPGAARGRYASSGATGRVRHRGYSDTERYLYC
RAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLIL
QANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRN
NFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRH
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKK
RPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNR
PLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLL
STPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAV
GFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSG
VLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISP
MCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSP
APDDQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEI
PLDEQVEEETVGEEEDSQPEACVIEDHSPDT
NT seq
2436 nt
NT seq
+upstream
nt +downstream
nt
atggaggcagagggcagcagcgtgccagcccaggcgggcagcgacgagggcagcgacggc
gccggaggggccacactcaaagcccccaagcacctctggaggcacgagcagcaccaccag
tacccgctccggcagccccagttccgcctcctgcacccccatcaccacctgcccccgcca
ccgccgccctcgccccagccccagccccagccccagtgtccgctgcaaccgcccccgcca
ccccccctgccaccgcccccgccgctgcccggggctgctcgcggccgctacgcctcgagc
ggggccaccggccgggtccgacatcgcggctactcggacaccgagcgctacctgtactgc
cgtgccatggaccgcacctcctacgccgtggagactggccaccggcccggcctgaagaaa
tccaggatgtcctggccctcctcgttccagggactcaggcgttttgatgtggacaatggc
acatctgcgggacggagtcccttggatcccatgaccagcccaggatctgggctaattctc
caagcaaactttgtccacagtcaacgtcgagagtcctttctgtatcgatccgacagcgat
tatgacctgtctccaaagtctatgtcccggaactcctccattgccagtgatatacatgga
gatgacttgattgtgactccatttgctcaggtcttggccagcctgcgaactgtgcgaaac
aactttgctgcgttaactaatttgcaagatcgagcacctagcaaaagatcacccatgtgc
aaccaaccatccatcaacaaagccaccataacagaggaggcctaccagaaactggccagc
gagaccctggaggagctggactggtgtctggaccagctagagacgctgcagaccaggcac
tccgtcagtgagatggcctccaacaagtttaaaaggatgcttaatcgggagctcacccat
ctctctgaaatgagtcggtctggaaatcaagtgtcagagtatatatcaaacacattctta
gataagcaacatgaagtggaaattccttctccaactcagaaggaaaaggagaaaaagaaa
aggccaatgtctcagatcagtggggtcaagaagttgatgcacagctccagtttgacaaat
tcaagcatcccaagatttggggttaaaactgaacaagaggatgtccttgccaaggaacta
gaagatgtgaataaatggggtcttcatgttttcagaatagcagagctgtctggtaaccgg
cctttgactgttatcatgcatactatttttcaggaacgggatttattaaaaacatttaaa
attccagtagacactttaattacataccttatgaccctggaagaccattatcatgctgac
gtggcctaccacaacaatattcatgctgcagatgtagtccagtcaacacatgtgctgtta
tctacacctgctttggaggctgtgtttacagatttggagattcttgcagcaatttttgct
agtgcaatacatgatgtagatcatcccggtgtgtcaaatcagtttctgatcaatacaaac
tccgaacttgccttgatgtacaatgattcttctgtcttggagaaccatcatttggctgtg
ggctttaagttgcttcaggaagaaaactgtgatattttccagaatttgaccaaaaagcaa
agacaatcattaaggaagatggtcattgacattgtacttgcaacagacatgtcaaaacac
atgaatctactggctgatttgaaaactatggttgaaactaagaaagtgacaagttctgga
gttcttcttcttgataattattctgataggattcaggtccttcagaatatggtgcactgt
gcagacctgagcaaccccacgaagcctctccagctgtaccgccagtggacggaccgcatc
atggaggagttcttccgccaaggagacagagagagggagcggggcatggagatcagtccc
atgtgtgacaagcacaatgcatctgtggaaaagtcacaggtgggcttcatagactatatt
gttcatcctctctgggagacatgggcagacctcgtgcatcctgacgcccaggacattctg
gacactttggaggacaatcgtgaatggtaccagagcacaattcctcagagcccctcccca
gcgcctgatgaccaggaagaaggccggcagggtcaaaccgagaagttccagtttgaactc
actttagaggaagatggcgagtccgacaccgaaaaggacagtggaagtcaggtggaagaa
gacactagctgcagtgactccaagactctctgtactcaagactcggagtctactgaaatt
ccccttgatgagcaggtggaagaggagacagtgggagaggaagaagacagccagcccgaa
gcctgtgtaatagaagatcattctcctgacacgtaa
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